product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse/Rat/Porcine/Equine CD44 Antibody
catalog :
AF6127
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 9
Reference
Kruk P, Nader K, Skupien Jaroszek A, W xf3 jtowicz T, Buszka A, Olech Kocha x144 czyk G, et al. Astrocytic CD44 Deficiency Reduces the Severity of Kainate-Induced Epilepsy. Cells. 2023;12: pubmed publisher
Jian F, Bao P, Li W, Cui Y, Hong H. Negative regulation of CD44st by miR-138-5p affects the invasive ability of breast cancer cells and patient prognosis after breast cancer surgery. BMC Cancer. 2023;23:269 pubmed publisher
Puri S, Moreno I, Sun M, Verma S, Lin X, Gesteira T, et al. Hyaluronan supports the limbal stem cell phenotype during ex vivo culture. Stem Cell Res Ther. 2022;13:384 pubmed publisher
Luci C, Vieira E, Bourinet M, Rousseau D, Bonnafous S, Patouraux S, et al. SYK-3BP2 Pathway Activity in Parenchymal and Myeloid Cells Is a Key Pathogenic Factor in Metabolic Steatohepatitis. Cell Mol Gastroenterol Hepatol. 2022;13:173-191 pubmed publisher
Hasib A, Hennayake C, Bracy D, Bugler Lamb A, Lantier L, Khan F, et al. CD44 contributes to hyaluronan-mediated insulin resistance in skeletal muscle of high-fat-fed C57BL/6 mice. Am J Physiol Endocrinol Metab. 2019;317:E973-E983 pubmed publisher
Aleman J, George S, Herberg S, Devarasetty M, Porada C, Skardal A, et al. Deconstructed Microfluidic Bone Marrow On-A-Chip to Study Normal and Malignant Hemopoietic Cell-Niche Interactions. Small. 2019;15:e1902971 pubmed publisher
Liu C, Yin G, Sun Y, Lin Y, Xie Z, English A, et al. Effect of exosomes from adipose-derived stem cells on the apoptosis of Schwann cells in peripheral nerve injury. CNS Neurosci Ther. 2020;26:189-196 pubmed publisher
D Ascola A, Scuruchi M, Avenoso A, Bruschetta G, Campo S, Mandraffino G, et al. Serglycin is involved in inflammatory response in articular mouse chondrocytes. Biochem Biophys Res Commun. 2018;499:506-512 pubmed publisher
Jin F, Jiang K, Ji S, Wang L, Ni Z, Huang F, et al. Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex. Hum Mol Genet. 2017;26:407-419 pubmed publisher
product information
brand :
R&D Systems
master code :
AF6127
SKU :
AF6127
product name :
Mouse/Rat/Porcine/Equine CD44 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse/Rat/Porcine/Equine CD44 Antibody from R&D Systems is a sheep polyclonal antibody to CD44. This antibody reacts with equine,human,mouse,porcine,rat. The Mouse/Rat/Porcine/Equine CD44 Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry-Paraffin,Flow Cytometry,Simple Western,Blockade of Receptor-ligand Interaction,Immunocytochemistry,CyTOF-ready.
target :
CD44
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Simple Western 10 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, Blockade of Receptor-ligand Interaction, Immunocytochemistry 5-15 ug/mL, CyTOF-ready
host :
Sheep
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant mouse CD44, Gln25-Thr224, Accession # NP_033981
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Equine,Human,Mouse,Porcine,Rat
specificity :
Detects mouse and rat CD44 in direct ELISAs and Western blots. In direct ELISAs, approximately 35% cross-reactivity with recombinant human CD44 is observed.
gene symbol :
CD44
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Mouse and Rat CD44 antibody by Western Blot.
accessionNumbers :
NP_033981
applications :
Flow Cytometry,Simple Western,Blockade of Receptor-ligand Interaction,Immunocytochemistry,CyTOF-ready,Western Blot,Immunohistochemistry-Paraffin,Neutralization
USD :
509 USD
alt names :
CD44, CD44 antigen, CD44 molecule (Indian blood group), CD44R, CDw44, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan sulfate proteoglycan, Hermes antigen, homing function and Indian blood group system, HUTCH-I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU2CD44 antigen (homing function and Indian blood group system), MDU3, MDU3CDW44, MIC4, MIC4MGC10468, MUTCH-I, Pgp1, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.