product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse IL-21 Antibody
catalog :
AF594
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, bovine
application :
western blot, ELISA, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 46
Reference
Akgul A, Freguia C, Maddaloni M, Hoffman C, Voigt A, Nguyen C, et al. Treatment with a Lactococcus lactis that chromosomally express E. coli cfaI mitigates salivary flow loss in a Sjögren's syndrome-like disease. Sci Rep. 2023;13:19489 pubmed publisher
Matsumoto D, Toba H, Kenzaki K, Sakiyama S, Sakamoto S, Takashima M, et al. Lung regeneration with rat fetal lung implantation and promotion of alveolar stem cell differentiation by corticosteroids. Regen Ther. 2023;24:426-433 pubmed publisher
Roux I, Fenollar Ferrer C, Lee H, Chattaraj P, Lopez I, Han K, et al. CHD7 variants associated with hearing loss and enlargement of the vestibular aqueduct. Hum Genet. 2023;142:1499-1517 pubmed publisher
Freitas Andrade M, Comin C, Van Dyken P, Ouellette J, Raman Nair J, Blakeley N, et al. Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation. Nat Commun. 2023;14:4965 pubmed publisher
Castaneda D, Jangra S, Yurieva M, Martinek J, Callender M, Coxe M, et al. Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia. iScience. 2023;26:107374 pubmed publisher
Oyler B, Valencia D xe1 vila J, Moysi E, Molyvdas A, Ioannidou K, March K, et al. Multilevel human secondary lymphoid immune system compartmentalization revealed by complementary imaging approaches. iScience. 2023;26:107261 pubmed publisher
Ugur M, Labios R, Fenton C, Kn xf6 pper K, Jobin K, Imdahl F, et al. Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks. Immunity. 2023;56:1778-1793.e10 pubmed publisher
Pizzato H, Alonso Guallart P, Woods J, Johannesson B, Connelly J, Fehniger T, et al. Engineering Human Pluripotent Stem Cell Lines to Evade Xenogeneic Transplantation Barriers. bioRxiv. 2023;: pubmed publisher
Schmidt E, Lamprinaki D, McCord K, Joe M, Sojitra M, Waldow A, et al. Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket. Nat Commun. 2023;14:2327 pubmed publisher
Li H, Br xe4 unig S, Dhapolar P, Karlsson G, Lang S, Scheding S. Identification of phenotypically, functionally, and anatomically distinct stromal niche populations in human bone marrow based on single-cell RNA sequencing. elife. 2023;12: pubmed publisher
Sreekumar S, Zhou D, Mpoy C, Schenk E, Scott J, Arbeit J, et al. Preclinical Efficacy of a PARP-1 Targeted Auger-Emitting Radionuclide in Prostate Cancer. Int J Mol Sci. 2023;24: pubmed publisher
Dart S, Prosser A, Huang W, Liu L, Lucas A, Delriviere L, et al. Subset-specific Retention of Donor Myeloid Cells After Major Histocompatibility Complex-matched and Mismatched Liver Transplantation. Transplantation. 2023;107:1502-1512 pubmed publisher
Blount Q, Hernandez Morato I, Moayedi Y, Pitman M. Expression of Glial Cell-Derived Neurotrophic Factor Receptors Within Nucleus Ambiguus During Rat Development. Laryngoscope. 2023;133:2240-2247 pubmed publisher
Huang S, Thomsson K, Jin C, Ryberg H, Das N, Struglics A, et al. Truncated lubricin glycans in osteoarthritis stimulate the synoviocyte secretion of VEGFA, IL-8, and MIP-1α: Interplay between O-linked glycosylation and inflammatory cytokines. Front Mol Biosci. 2022;9:942406 pubmed publisher
Orbach S, Brooks M, Zhang Y, Campit S, Bushnell G, Decker J, et al. Single-cell RNA-sequencing identifies anti-cancer immune phenotypes in the early lung metastatic niche during breast cancer. Clin Exp Metastasis. 2022;39:865-881 pubmed publisher
Shemesh A, Pickering H, Roybal K, Lanier L. Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion. J Exp Med. 2022;219: pubmed publisher
Varn F, Johnson K, Martinek J, Huse J, Nasrallah M, Wesseling P, et al. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell. 2022;185:2184-2199.e16 pubmed publisher
Gerlini G, Di Gennaro P, Pimpinelli N, Sestini S, Borgognoni L. Tolerogenic IDO1+CD83- Langerhans Cells in Sentinel Lymph Nodes of Patients with Melanoma. Int J Mol Sci. 2022;23: pubmed publisher
Blondin Ladrie L, Fourcade L, Modica A, Aranguren M, de Montigny N, Labb xe9 A, et al. Monocyte Gene and Molecular Expression Profiles Suggest Distinct Effector and Regulatory Functions in Beninese HIV Highly Exposed Seronegative Female Commercial Sex Workers. Viruses. 2022;14: pubmed publisher
Kim E, Yoon B, Lee S, Choi M, Kim E, Lee B, et al. Fecal microbiota transplantation ameliorates atherosclerosis in mice with C1q/TNF-related protein 9 genetic deficiency. Exp Mol Med. 2022;54:103-114 pubmed publisher
El Khoueiry C, Cabungcal J, Rov xf3 Z, Fournier M, Do K, Steullet P. Developmental oxidative stress leads to T-type Ca2+ channel hypofunction in thalamic reticular nucleus of mouse models pertinent to schizophrenia. Mol Psychiatry. 2022;27:2042-2051 pubmed publisher
Bouchard G, Garcia Marques F, Karacosta L, Zhang W, Bermudez A, Riley N, et al. Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4-pRB Axis in Fibroblasts at the Invasive Tumor Edge. Cancer Res. 2022;82:648-664 pubmed publisher
Matsunaga M, Kimura M, Ouchi T, Nakamura T, Ohyama S, Ando M, et al. Mechanical Stimulation-Induced Calcium Signaling by Piezo1 Channel Activation in Human Odontoblast Reduces Dentin Mineralization. Front Physiol. 2021;12:704518 pubmed publisher
Zhang C, Li Y, Qin J, Yu C, Ma G, Chen H, et al. TMT-Based Quantitative Proteomic Analysis Reveals the Effect of Bone Marrow Derived Mesenchymal Stem Cell on Hair Follicle Regeneration. Front Pharmacol. 2021;12:658040 pubmed publisher
Epperly M, Shields D, Fisher R, Hou W, Wang H, Hamade D, et al. Radiation-Induced Senescence in p16+/LUC Mouse Lung Compared to Bone Marrow Multilineage Hematopoietic Progenitor Cells. Radiat Res. 2021;196:235-249 pubmed publisher
Mohamed H, Gebski E, Reyes R, Beane S, Wigdahl B, Krebs F, et al. Differential Effect of Non-Thermal Plasma RONS on Two Human Leukemic Cell Populations. Cancers (Basel). 2021;13: pubmed publisher
Daemen S, Chan M, Schilling J. Comprehensive analysis of liver macrophage composition by flow cytometry and immunofluorescence in murine NASH. STAR Protoc. 2021;2:100511 pubmed publisher
Lef xe8 vre L, Iacovoni J, Martini H, Belli xe8 re J, Maggiorani D, Dutaur M, et al. Kidney inflammaging is promoted by CCR2+ macrophages and tissue-derived micro-environmental factors. Cell Mol Life Sci. 2021;78:3485-3501 pubmed publisher
Lamers M, van der Vaart J, Knoops K, Riesebosch S, Breugem T, Mykytyn A, et al. An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells. EMBO J. 2021;40:e105912 pubmed publisher
Villarreal Ponce A, Tiruneh M, Lee J, Guerrero Juarez C, Kuhn J, David J, et al. Keratinocyte-Macrophage Crosstalk by the Nrf2/Ccl2/EGF Signaling Axis Orchestrates Tissue Repair. Cell Rep. 2020;33:108417 pubmed publisher
Melchor S, Hatter J, Castillo É, Saunders C, Byrnes K, Sanders I, et al. T. gondii infection induces IL-1R dependent chronic cachexia and perivascular fibrosis in the liver and skeletal muscle. Sci Rep. 2020;10:15724 pubmed publisher
Vaibhav K, Braun M, Alverson K, Khodadadi H, Kutiyanawalla A, Ward A, et al. Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury. Sci Adv. 2020;6:eaax8847 pubmed publisher
Shen Z, Wu J, Gao Z, Wang J, Zhu H, Mao R, et al. Characterization of IL-21-expressing recombinant hepatitis B virus (HBV) as a therapeutic agent targeting persisting HBV infection. Theranostics. 2020;10:5600-5612 pubmed publisher
Wagner M, Yoshihara M, Douagi I, Damdimopoulos A, Panula S, Petropoulos S, et al. Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells. Nat Commun. 2020;11:1147 pubmed publisher
Gleeson J, Estrada H, Yamashita M, Svendsen C, Targan S, Barrett R. Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD. Int J Mol Sci. 2020;21: pubmed publisher
Dewald H, Hurley H, Fitzgerald Bocarsly P. Regulation of Transcription Factor E2-2 in Human Plasmacytoid Dendritic Cells by Monocyte-Derived TNFα. Viruses. 2020;12: pubmed publisher
Mir R, Schaut R, Allen H, Looft T, Loving C, Kudva I, et al. Cattle intestinal microbiota shifts following Escherichia coli O157:H7 vaccination and colonization. PLoS ONE. 2019;14:e0226099 pubmed publisher
Vogt M, Lahon A, Arya R, Spencer Clinton J, Rico Hesse R. Dengue viruses infect human megakaryocytes, with probable clinical consequences. PLoS Negl Trop Dis. 2019;13:e0007837 pubmed publisher
Himburg H, Roos M, Fang T, Zhang Y, Termini C, Schlussel L, et al. Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling. J Clin Invest. 2020;130:315-328 pubmed publisher
Hellinen L, Pirskanen L, Tengvall Unadike U, Urtti A, Reinisalo M. Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties. Pharmaceutics. 2019;11: pubmed publisher
Wang C, Ming B, Wu X, Wu T, Cai S, Hu P, et al. Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response. EBioMedicine. 2019;45:578-587 pubmed publisher
Ziffels B, Stringhini M, Probst P, Fugmann T, Sturm T, Neri D. Antibody-based delivery of cytokine payloads to carbonic anhydrase IX leads to cancer cures in immunocompetent tumor-bearing mice. Mol Cancer Ther. 2019;: pubmed publisher
Schaut R, Boggiatto P, Loving C, Sharma V. Cellular and Mucosal Immune Responses Following Vaccination with Inactivated Mutant of Escherichia coli O157:H7. Sci Rep. 2019;9:6401 pubmed publisher
Williams P, Braine C, Kizhatil K, Foxworth N, Tolman N, Harder J, et al. Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma. Mol Neurodegener. 2019;14:6 pubmed publisher
Hooper K, Kong W, Ganea D. Prostaglandin E2 inhibits Tr1 cell differentiation through suppression of c-Maf. PLoS ONE. 2017;12:e0179184 pubmed publisher
Eri T, Kawahata K, Kanzaki T, Imamura M, Michishita K, Akahira L, et al. Intestinal microbiota link lymphopenia to murine autoimmunity via PD-1+CXCR5-/dim B-helper T cell induction. Sci Rep. 2017;7:46037 pubmed publisher
product information
master code :
AF594
SKU :
AF594
product name :
Mouse IL-21 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse IL-21 Antibody from R&D Systems is a goat polyclonal antibody to IL-21. This antibody reacts with bovine,human,mouse,transgenic mouse. The Mouse IL-21 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,ELISA Development,ELISpot Development,Flow Cytometry,Neutralization,ELISA Capture,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture (Matched Antibody Pair).
target :
IL-21
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant mouse IL-21 (R D Systems, Catalog # 594-ML), Pro25-Ser146, Accession # Q9ES17
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Bovine,Human,Mouse
specificity :
Detects mouse IL-21 in ELISAs and Western blots. In sandwich ELISAs, less than 0.5% cross-reactivity with recombinant mouse (rm) IL-2, rmIL-4, rmIL-15, and recombinant human IL-21 is observed.
gene symbol :
IL21
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
IL-21 antibody in Mouse Splenocytes by Immunocytochemistry (ICC).
accessionNumbers :
Q9ES17
applications :
Western Blot,ELISA Development,ELISpot Development,Flow Cytometry,Neutralization,ELISA Capture,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture (Matched Antibody Pair)
USD :
499 USD
alt names :
CVID11, IL21, IL-21Za11interleukin-21, interleukin 21, interleukin-21 isoform, Za11
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.