| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry; human; 1:200; loading ...; fig 1c
| Huang Y, Happonen K, Burrola P, O Connor C, Hah N, Huang L, et al. Microglia use TAM receptors to detect and engulf amyloid β plaques. Nat Immunol. 2021;22:586-594 pubmed publisher |
| Tufan T, Cömertpay G, Villani A, Nelson G, Terekhova M, Kelley S, et al. Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release. Nature. 2024;628:408-415 pubmed publisher |
| Pop O, Geng A, Flint E, Singanayagam A, Ercan C, Possamai L, et al. AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells. Cell Mol Gastroenterol Hepatol. 2023;16:17-37 pubmed publisher |
| L xe1 zaro I, Bobi J, Cof xe1 n M, Kapravelou G, Amor A, Surra J, et al. Walnut inclusion in a palm oil-based atherogenic diet promotes traits predicting stable atheroma plaque in Apoe-deficient mice. Front Nutr. 2023;10:1079407 pubmed publisher |
| Huang Y, Lemke G. Adaptable toolbox to characterize Alzheimer's disease pathology in mouse models. STAR Protoc. 2022;3:101891 pubmed publisher |
| Feriotti C, S xe1 Pessoa J, Calder xf3 n Gonz xe1 lez R, Gu L, Morris B, Sugisawa R, et al. Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity. Cell Rep. 2022;40:111167 pubmed publisher |
| Jung H, Lee S, Lim S, Choi H, Choi Y, Kim M, et al. Anti-inflammatory clearance of amyloid-β by a chimeric Gas6 fusion protein. Nat Med. 2022;28:1802-1812 pubmed publisher |
| Manickam V, Dhawan U, Singh D, Gupta M, Subramanian M. Pomegranate Peel Extract Decreases Plaque Necrosis and Advanced Atherosclerosis Progression in Apoe -/- Mice. Front Pharmacol. 2022;13:888300 pubmed publisher |
| Zheng L, Jia J, Chen Y, Liu R, Cao R, Duan M, et al. Pentoxifylline alleviates ischemic white matter injury through up-regulating Mertk-mediated myelin clearance. J Neuroinflammation. 2022;19:128 pubmed publisher |
| Roy E, Chiu G, Li S, Propson N, Kanchi R, Wang B, et al. Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques. Immunity. 2022;55:879-894.e6 pubmed publisher |
| Liang X, Luo M, Shao B, Yang J, Tong A, Wang R, et al. Phosphatidylserine released from apoptotic cells in tumor induces M2-like macrophage polarization through the PSR-STAT3-JMJD3 axis. Cancer Commun (Lond). 2022;42:205-222 pubmed publisher |
| Huang X, Liu C, Kong N, Xiao Y, Yurdagul A, Tabas I, et al. Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages. Nat Protoc. 2022;17:748-780 pubmed publisher |
| Chen C, Liu Y. MERTK Inhibition: Potential as a Treatment Strategy in EGFR Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer. Pharmaceuticals (Basel). 2021;14: pubmed publisher |
| Esposito N, Mazzoni F, Vargas J, Finnemann S. Diurnal Photoreceptor Outer Segment Renewal in Mice Is Independent of Galectin-3. Invest Ophthalmol Vis Sci. 2021;62:7 pubmed publisher |
| Rosin J, Marsters C, Malik F, Far R, Adnani L, Schuurmans C, et al. Embryonic Microglia Interact with Hypothalamic Radial Glia during Development and Upregulate the TAM Receptors MERTK and AXL following an Insult. Cell Rep. 2021;34:108587 pubmed publisher |
| Wu H, Zheng J, Xu S, Fang Y, Wu Y, Zeng J, et al. Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury. J Neuroinflammation. 2021;18:2 pubmed publisher |
| Madore C, Leyrolle Q, Morel L, Rossitto M, Greenhalgh A, Delpech J, et al. Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain. Nat Commun. 2020;11:6133 pubmed publisher |
| Lu C, Santosa K, Jablonka Shariff A, Vannucci B, Fuchs A, Turnbull I, et al. Macrophage-Derived Vascular Endothelial Growth Factor-A Is Integral to Neuromuscular Junction Reinnervation after Nerve Injury. J Neurosci. 2020;40:9602-9616 pubmed publisher |
| DuBois J, Ray A, Davies P, Shafit Zagardo B. Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis. J Neuroinflammation. 2020;17:324 pubmed publisher |
| Konishi H, Okamoto T, Hara Y, Komine O, Tamada H, Maeda M, et al. Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction. EMBO J. 2020;39:e104464 pubmed publisher |
| Tao W, Yurdagul A, Kong N, Li W, Wang X, Doran A, et al. siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice. Sci Transl Med. 2020;12: pubmed publisher |
| Moon B, Lee J, Lee S, Min C, Moon H, Kim D, et al. Mertk Interacts with Tim-4 to Enhance Tim-4-Mediated Efferocytosis. Cells. 2020;9: pubmed publisher |
| Damisah E, Hill R, Rai A, Chen F, Rothlin C, Ghosh S, et al. Astrocytes and microglia play orchestrated roles and respect phagocytic territories during neuronal corpse removal in vivo. Sci Adv. 2020;6:eaba3239 pubmed publisher |
| Zag xf3 rska A, Trav xe9 s P, Jim xe9 nez Garc xed a L, Strickland J, Oh J, Tapia F, et al. Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer. Life Sci Alliance. 2020;3: pubmed publisher |
| Tutusaus A, de Gregorio E, Cucarull B, Cristóbal H, Aresté C, Graupera I, et al. A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target. Cell Mol Gastroenterol Hepatol. 2020;9:349-368 pubmed publisher |
| Egaña Gorroño L, Chinnasamy P, Casimiro I, Almonte V, Parikh D, Oliveira Paula G, et al. Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques. Atherosclerosis. 2019;289:184-194 pubmed publisher |
| Kasikara C, Davra V, Calianese D, Geng K, Spires T, Quigley M, et al. Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer. Cancer Res. 2019;79:2669-2683 pubmed publisher |
| Aran D, Looney A, Liu L, Wu E, Fong V, Hsu A, et al. Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. Nat Immunol. 2019;20:163-172 pubmed publisher |
| Ma J, Ng W, Zappia L, Gearing L, Olshansky M, Pham K, et al. Unique Transcriptional Architecture in Airway Epithelial Cells and Macrophages Shapes Distinct Responses following Influenza Virus Infection Ex Vivo. J Virol. 2019;93: pubmed publisher |
| Thomas D, Doran A, Fotakis P, Westerterp M, Antonson P, Jiang H, et al. LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux. Cell Rep. 2018;25:3774-3785.e4 pubmed publisher |
| Du W, Huang H, Sorrelle N, Brekken R. Sitravatinib potentiates immune checkpoint blockade in refractory cancer models. JCI Insight. 2018;3: pubmed publisher |
| Zhang L, DeBerge M, Wang J, Dangi A, Zhang X, Schroth S, et al. Receptor tyrosine kinase MerTK suppresses an allogenic type I IFN response to promote transplant tolerance. Am J Transplant. 2019;19:674-685 pubmed publisher |
| Waterborg C, Beermann S, Broeren M, Bennink M, Koenders M, van Lent P, et al. Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models. Front Immunol. 2018;9:742 pubmed publisher |
| Brosius Lutz A, Chung W, Sloan S, Carson G, Zhou L, Lovelett E, et al. Schwann cells use TAM receptor-mediated phagocytosis in addition to autophagy to clear myelin in a mouse model of nerve injury. Proc Natl Acad Sci U S A. 2017;114:E8072-E8080 pubmed publisher |
| Canfrán Duque A, Rotllan N, Zhang X, Fernández Fuertes M, Ramírez Hidalgo C, Araldi E, et al. Macrophage deficiency of miR-21 promotes apoptosis, plaque necrosis, and vascular inflammation during atherogenesis. EMBO Mol Med. 2017;9:1244-1262 pubmed publisher |
| Bellesi M, de Vivo L, Chini M, Gilli F, Tononi G, Cirelli C. Sleep Loss Promotes Astrocytic Phagocytosis and Microglial Activation in Mouse Cerebral Cortex. J Neurosci. 2017;37:5263-5273 pubmed publisher |
| Voronova A, Yuzwa S, Wang B, Zahr S, Syal C, Wang J, et al. Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain. Neuron. 2017;94:500-516.e9 pubmed publisher |
| Tufail Y, Cook D, Fourgeaud L, Powers C, Merten K, Clark C, et al. Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia. Neuron. 2017;93:574-586.e8 pubmed publisher |
| Nassar M, Tabib Y, Capucha T, Mizraji G, Nir T, Pevsner Fischer M, et al. GAS6 is a key homeostatic immunological regulator of host-commensal interactions in the oral mucosa. Proc Natl Acad Sci U S A. 2017;114:E337-E346 pubmed publisher |
| Suresh Babu S, Thandavarayan R, Joladarashi D, Jeyabal P, Krishnamurthy S, Bhimaraj A, et al. MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes. Sci Rep. 2016;6:36207 pubmed publisher |
| Kim S, Lim E, Yoon Y, Ahn Y, Park E, Kim H, et al. Liver X receptor and STAT1 cooperate downstream of Gas6/Mer to induce anti-inflammatory arginase 2 expression in macrophages. Sci Rep. 2016;6:29673 pubmed publisher |
| Cai B, Thorp E, Doran A, Subramanian M, Sansbury B, Lin C, et al. MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation. Proc Natl Acad Sci U S A. 2016;113:6526-31 pubmed publisher |
| Fourgeaud L, Traves P, Tufail Y, Leal Bailey H, Lew E, Burrola P, et al. TAM receptors regulate multiple features of microglial physiology. Nature. 2016;532:240-244 pubmed publisher |
