product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat Arginase 1/ARG1 Antibody
catalog :
AF5868
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, flow cytometry
more info or order :
citations: 14
Reference
Rebou xe7 as Silva J, Amorim N, Jesus Santos F, de Lima J, Lima J, Berretta A, et al. Leishmanicidal and immunomodulatory properties of Brazilian green propolis extract (EPP-AF®) and a gel formulation in a pre-clinical model. Front Pharmacol. 2023;14:1013376 pubmed publisher
Komori T, Morikawa Y. Essential roles of the cytokine oncostatin M in crosstalk between muscle fibers and immune cells in skeletal muscle after aerobic exercise. J Biol Chem. 2022;298:102686 pubmed publisher
Li D, Wang G. Asiaticoside reverses M2 phenotype macrophage polarization-evoked osteosarcoma cell malignant behaviour by TRAF6/NF-κB inhibition. Pharm Biol. 2022;60:1635-1645 pubmed publisher
Tlili M, Acevedo H, Descoteaux A, Germain M, Heinonen K. Cell-intrinsic Wnt4 ligand regulates mitochondrial oxidative phosphorylation in macrophages. J Biol Chem. 2022;298:102193 pubmed publisher
Zhou H, Yang P, Li H, Zhang L, Li J, Zhang T, et al. Carbon ion radiotherapy boosts anti-tumour immune responses by inhibiting myeloid-derived suppressor cells in melanoma-bearing mice. Cell Death Discov. 2021;7:332 pubmed publisher
Komarova E, Suezov R, Nikotina A, Aksenov N, Garaeva L, Shtam T, et al. Hsp70-containing extracellular vesicles are capable of activating of adaptive immunity in models of mouse melanoma and colon carcinoma. Sci Rep. 2021;11:21314 pubmed publisher
Diskin B, Adam S, Cassini M, Sanchez G, Liria M, Aykut B, et al. PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer. Nat Immunol. 2020;21:442-454 pubmed publisher
Ren W, Hou J, Yang C, Wang H, Wu S, Wu Y, et al. Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery. J Exp Clin Cancer Res. 2019;38:62 pubmed publisher
Gerber H, Mosser S, Boury Jamot B, Stumpe M, Piersigilli A, Goepfert C, et al. The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease. Acta Neuropathol Commun. 2019;7:13 pubmed publisher
Wosik J, Chen W, Qin K, Ghobrial R, Kubiak J, Kloc M. Magnetic Field Changes Macrophage Phenotype. Biophys J. 2018;114:2001-2013 pubmed publisher
Suwanpradid J, Shih M, Pontius L, Yang B, Birukova A, Guttman Yassky E, et al. Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. J Immunol. 2017;199:1827-1834 pubmed publisher
Maliver P, Festag M, Bennecke M, Christen F, Bánfai B, Lenz B, et al. Assessment of Preclinical Liver and Skeletal Muscle Biomarkers Following Clofibrate Administration in Wistar Rats. Toxicol Pathol. 2017;45:506-525 pubmed publisher
Nascimento D, Melo P, Piñeros A, Ferreira R, Cólon D, Donate P, et al. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population. Nat Commun. 2017;8:14919 pubmed publisher
Wagener J, MacCallum D, Brown G, Gow N. Candida albicans Chitin Increases Arginase-1 Activity in Human Macrophages, with an Impact on Macrophage Antimicrobial Functions. MBio. 2017;8: pubmed publisher
product information
master code :
AF5868
SKU :
AF5868
product name :
Human/Mouse/Rat Arginase 1/ARG1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse/Rat Arginase 1/ARG1 Antibody from R&D Systems is a sheep polyclonal antibody to Arginase 1/ARG1/liver Arginase. This antibody reacts with human,mouse,rat,transgenic mouse,xenograft. The Human/Mouse/Rat Arginase 1/ARG1 Antibody has been validated for the following applications: CyTOF-reported,ELISA Development (Capture),Flow Cytometry,Western Blot,Immunoprecipitation,Simple Western.
target :
Arginase 1/ARG1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Sheep
immunogen :
E. coli -derived recombinant human Arginase 1/ARG1, Met1-Lys322, Accession # P05089
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Xenograft
specificity :
Detects human, mouse, and rat Arginase 1/ARG1 in direct ELISAs and Western blots.
gene symbol :
ARG1
top caption :
Detection of Human and Rat Arginase 1/ARG1 antibody by Western Blot.
accessionNumbers :
P05089
applications :
ELISA Development (Capture),Flow Cytometry,Western Blot,Immunoprecipitation,Simple Western
USD :
479 USD
alt names :
AI, ARG1, arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, EC:3.5.3.1, Liver Arginase, Liver-type arginase, PGIF, Type I Arginase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.