Human/Mouse NKX6.1 Antibody | R&D Systems AF5857 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse NKX6.1 Antibody

catalog :

AF5857

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:3000; loading ...; fig 6d	Lasierra Losada M, Pauler M, Vandamme N, Goossens S, Berx G, Leppkes M, et al. Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells. Cell Death Discov. 2021;7:138 pubmed publisher
	Li X, Ma Z, Lui K. A differentiation protocol for the generation of pancreatic beta-like cells from human embryonic stem cells. STAR Protoc. 2023;4:102407 pubmed publisher
	Uhlemeyer C, M xfc ller N, Rieck M, Kuboth J, Schlegel C, Grie xdf K, et al. Selective ablation of P53 in pancreatic beta cells fails to ameliorate glucose metabolism in genetic, dietary and pharmacological models of diabetes mellitus. Mol Metab. 2023;67:101650 pubmed publisher
	Seo W, Yoon J, Lee J, Lee Y, Lee H, Geum D, et al. Modeling axonal regeneration by changing cytoskeletal dynamics in stem cell-derived motor nerve organoids. Sci Rep. 2022;12:2082 pubmed publisher
	Chhabra N, Amend A, Bastidas Ponce A, Sabrautzki S, Tarquis Medina M, Sachs S, et al. A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes. Mol Metab. 2021;54:101334 pubmed publisher
	Simone R, Javad F, Emmett W, Wilkins O, Almeida F, Barahona Torres N, et al. MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration. Nature. 2021;594:117-123 pubmed publisher
	Burtscher I, Tarquis Medina M, Salinno C, Schirge S, Beckenbauer J, Bakhti M, et al. Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line. Int J Mol Sci. 2021;22: pubmed publisher
	Singh R, Cottle L, Loudovaris T, Xiao D, Yang P, Thomas H, et al. Enhanced structure and function of human pluripotent stem cell-derived beta-cells cultured on extracellular matrix. Stem Cells Transl Med. 2021;10:492-505 pubmed publisher
	Chung H, Lee C, Hu J, Chou Y, Lin Y, Shih Y. NKX6.1 Represses Tumorigenesis, Metastasis, and Chemoresistance in Colorectal Cancer. Int J Mol Sci. 2020;21: pubmed publisher
	Ilievski V, Toth P, Valyi Nagy K, Valyi Nagy T, Green S, Marattil R, et al. Identification of a periodontal pathogen and bihormonal cells in pancreatic islets of humans and a mouse model of periodontitis. Sci Rep. 2020;10:9976 pubmed publisher
	Mahaddalkar P, Scheibner K, Pfluger S, Ansarullah -, Sterr M, Beckenbauer J, et al. Generation of pancreatic β cells from CD177+ anterior definitive endoderm. Nat Biotechnol. 2020;38:1061-1072 pubmed publisher
	Kim S, Whitener R, Peiris H, Gu X, Chang C, Lam J, et al. Molecular and genetic regulation of pig pancreatic islet cell development. Development. 2020;147: pubmed publisher
	Volta F, Scerbo M, Seelig A, Wagner R, O Brien N, Gerst F, et al. Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing. Nat Commun. 2019;10:5686 pubmed publisher
	Diekmann U, Wolling H, Dettmer R, Niwolik I, Naujok O, Buettner F. Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture. Sci Rep. 2019;9:996 pubmed publisher
	Memon B, Karam M, Al Khawaga S, Abdelalim E. Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1. Stem Cell Res Ther. 2018;9:15 pubmed publisher
	Bader E, Migliorini A, Gegg M, Moruzzi N, Gerdes J, Roscioni S, et al. Identification of proliferative and mature ?-cells in the islets of Langerhans. Nature. 2016;535:430-4 pubmed

product information

brand :

R&D Systems

master code :

AF5857

SKU :

AF5857

product name :

Human/Mouse NKX6.1 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse NKX6.1 Antibody from R&D Systems is a goat polyclonal antibody to NKX6.1. This antibody reacts with human,mouse. The Human/Mouse NKX6.1 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Simple Western.

target :

NKX6.1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Simple Western 10 ug/mL, Immunohistochemistry 5-15 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant human NKX6.1, Met1-Pro120, Accession # NP_006159

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human and mouse NKX6.1 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human NKX3.1 is observed.

gene symbol :

NKX6-1

top caption :

Detection of Mouse NKX6.1 antibody by Western Blot.

accessionNumbers :

NP_006159

applications :

Simple Western,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry

USD :

509 USD

alt names :

Homeobox protein NK-6 homolog A, NK homeo box, family 6, member A, NK homeobox (Drosophila), family 6, A, NK homeobox, family 6, A, NK6 homeobox 1, NK6 transcription factor homolog A, NK6 transcription factor related, locus 1, NK6 transcription factor related, locus 1 (Drosophila), NKX6.1, NKX6-1, NKX6A, NKX6Ahomeobox protein Nkx-6.1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage