product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse CX3CR1 Antibody
catalog :
AF5825
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 10
Reference
Long J, Liu H, Qiu Z, Xiao Z, Lu Z. Glabridin Therapy Reduces Chronic Allodynia, Spinal Microgliosis, and Dendritic Spine Generation by Inhibiting Fractalkine-CX3CR1 Signaling in a Mouse Model of Tibial Fractures. Brain Sci. 2023;13: pubmed publisher
Wu C, Peng P, Renn T, Lee C, Chang T, Wei A, et al. CX3CL1 induces cell migration and invasion through ICAM-1 expression in oral squamous cell carcinoma cells. J Cell Mol Med. 2023;27:1509-1522 pubmed publisher
Brassington K, Kanellakis P, Cao A, Toh B, Peter K, Bobik A, et al. Crosstalk between cytotoxic CD8+ T cells and stressed cardiomyocytes triggers development of interstitial cardiac fibrosis in hypertensive mouse hearts. Front Immunol. 2022;13:1040233 pubmed publisher
Tsubaki T, Kadonosono T, Sakurai S, Shiozawa T, Goto T, Sakai S, et al. Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment. Oncotarget. 2018;9:11209-11226 pubmed publisher
Han K, Arlian B, Macauley M, Paulson J, Lerner R. Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid ?. Proc Natl Acad Sci U S A. 2018;115:E372-E381 pubmed publisher
Yano T, Ohira M, Nakano R, Tanaka Y, Ohdan H. Hepatectomy leads to loss of TRAIL-expressing liver NK cells via downregulation of the CXCL9-CXCR3 axis in mice. PLoS ONE. 2017;12:e0186997 pubmed publisher
Mussar K, Pardike S, Hohl T, Hardiman G, Cirulli V, Crisa L. A CCR2+ myeloid cell niche required for pancreatic β cell growth. JCI Insight. 2017;2: pubmed publisher
Saika R, Sakuma H, Noto D, Yamaguchi S, Yamamura T, Miyake S. MicroRNA-101a regulates microglial morphology and inflammation. J Neuroinflammation. 2017;14:109 pubmed publisher
Maphis N, Jiang S, Xu G, Kokiko Cochran O, Roy S, Van Eldik L, et al. Selective suppression of the ? isoform of p38 MAPK rescues late-stage tau pathology. Alzheimers Res Ther. 2016;8:54 pubmed
Fan Y, Xiong X, Zhang Y, Yan D, Jian Z, Xu B, et al. MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice. J Am Heart Assoc. 2016;5: pubmed publisher
product information
brand :
R&D Systems
master code :
AF5825
SKU :
AF5825
product name :
Human/Mouse CX3CR1 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse CX3CR1 Antibody from R&D Systems is a goat polyclonal antibody to CX3CR1. This antibody reacts with human,mouse. The Human/Mouse CX3CR1 Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Western Blot,Flow Cytometry,Immunohistochemistry-Frozen,In vivo assay,CyTOF-ready.
target :
CX3CR1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, CyTOF-ready
host :
Goat
immunogen :
E. coli -derived recombinant mouse CX3CR1, Met1-Thr32, Leu92-Lys104, Thr169-Val196, Lys258-Leu274, Accession # Q9Z0D9
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human and mouse CX3CR1 in direct ELISAs and Western blots.
gene symbol :
CX3CR1
top caption :
Detection of Human and Mouse CX3CR1 antibody by Western Blot.
accessionNumbers :
Q9Z0D9
applications :
CyTOF-ready,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry
USD :
499 USD
alt names :
Beta chemokine receptor-like 1, CCRL1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, CMKbRL1, CMK-BRL1, CMK-BRL-1, CMKDR1, CX3C chemokine receptor 1, Fractalkine receptor, G protein-coupled receptor 13, GPR13G-protein coupled receptor 13, GPRV28, V28, V28C-X3-C CKR-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.