product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Mouse IL-22 Antibody
catalog :
AF582
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 11
Reference
Olivera I, Bola xf1 os E, Gonzalez Gomariz J, Hervas Stubbs S, Mari xf1 o K, Luri Rey C, et al. mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy. Cell Rep Med. 2023;4:100978 pubmed publisher
Tan C, Hong G, Wang Z, Duan C, Hou L, Wu J, et al. Promoting Effect of L-Fucose on the Regeneration of Intestinal Stem Cells through AHR/IL-22 Pathway of Intestinal Lamina Propria Monocytes. Nutrients. 2022;14: pubmed publisher
Ninnemann J, Winsauer C, Bondareva M, K xfc hl A, Lozza L, Durek P, et al. TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability. Mucosal Immunol. 2022;15:698-716 pubmed publisher
Iwanaga N, Sandquist I, Wanek A, McCombs J, Song K, Kolls J. Host immunology and rational immunotherapy for carbapenem-resistant Klebsiella pneumoniae infection. JCI Insight. 2020;5: pubmed publisher
Chen J, Haller C, Jernigan F, Koerner S, Wong D, Wang Y, et al. Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists. Sci Adv. 2020;6:eaay8230 pubmed publisher
Nakamoto N, Amiya T, Aoki R, Taniki N, Koda Y, Miyamoto K, et al. Commensal Lactobacillus Controls Immune Tolerance during Acute Liver Injury in Mice. Cell Rep. 2017;21:1215-1226 pubmed publisher
Broquet A, Jacqueline C, Davieau M, Besbes A, Roquilly A, Martin J, et al. Interleukin-22 level is negatively correlated with neutrophil recruitment in the lungs in a Pseudomonas aeruginosa pneumonia model. Sci Rep. 2017;7:11010 pubmed publisher
Lou H, Lu J, Choi E, Oh M, Jeong M, Barmettler S, et al. Expression of IL-22 in the Skin Causes Th2-Biased Immunity, Epidermal Barrier Dysfunction, and Pruritus via Stimulating Epithelial Th2 Cytokines and the GRP Pathway. J Immunol. 2017;198:2543-2555 pubmed publisher
Ji Y, Mittal S, Hwang H, Chang E, Lee J, Seo Y, et al. Lacrimal gland-derived IL-22 regulates IL-17-mediated ocular mucosal inflammation. Mucosal Immunol. 2017;10:1202-1210 pubmed publisher
Dong L, Helmke A, Waisman A, Haller H, Pich A, von Vietinghoff S. Surface-bound bovine serum albumin carrier protein as present in recombinant cytokine preparations amplifies T helper 17 cell polarization. Sci Rep. 2016;6:36598 pubmed publisher
Ibiza S, García Cassani B, Ribeiro H, Carvalho T, Almeida L, Marques R, et al. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 2016;535:440-443 pubmed publisher
product information
brand :
R&D Systems
master code :
AF582
SKU :
AF582
product name :
Mouse IL-22 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse IL-22 Antibody from R&D Systems is a goat polyclonal antibody to IL-22. This antibody reacts with mouse. The Mouse IL-22 Antibody has been validated for the following applications: Bioassay,ELISA Development,Flow Cytometry,Neutralization,Immunohistochemistry,Western Blot,ELISA Capture (Matched Antibody Pair).
target :
IL-22
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Neutralization 0.5-2.5 ug/mL, ELISA Capture (Matched Antibody Pair) 1-4 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant mouse IL-22, Leu34-Val179, Accession # Q9JJY9
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse IL-22 in ELISAs and Western blots. In sandwich immunoassays, approximately 75% cross-reactivity with recombinant rat IL-22 is observed and less than 25% cross-reactivity with recombinant human IL-22 is observed.
gene symbol :
IL22
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
IL-10 Secretion Induced by IL-22 and Neutralization by Mouse IL-22 Antibody.
accessionNumbers :
Q9JJY9
applications :
Western Blot,ELISA Capture (Matched Antibody Pair),Bioassay,ELISA Development,Flow Cytometry,Immunohistochemistry,Neutralization
USD :
519 USD
alt names :
Cytokine Zcyto18, IL-10-related T-cell-derived inducible factor, IL22, IL-D110, IL-TIF, ILTIFIL-10-related T-cell-derived-inducible factor, IL-TIFMGC79382, interleukin 22, interleukin-22, MGC79384, TIFa, TIFIL-23, zcyto18
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.