Mouse Siglec-E Antibody | R&D Systems AF5806 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Siglec-E Antibody

catalog :

AF5806

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 4d	Hsu Y, Hsu F, Chiang M, Tsai D, Li F, Angata T, et al. Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation. J Biomed Sci. 2021;28:5 pubmed publisher
	Borges T, Lima K, Murshid A, Lape I, Zhao Y, Rigo M, et al. Innate extracellular Hsp70 inflammatory properties are mediated by the interaction of Siglec-E and LOX-1 receptors. bioRxiv. 2023;: pubmed publisher
	Wang X, Liu M, Zhang J, Brown N, Zhang P, Zhang Y, et al. CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder. Cell Metab. 2022;34:1088-1103.e6 pubmed publisher
	Dharmadhikari G, Stolz K, Hauke M, Morgan N, Varki A, de Koning E, et al. Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes. Sci Rep. 2017;7:45319 pubmed publisher
	Schwarz F, Landig C, Siddiqui S, Secundino I, Olson J, Varki N, et al. Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen. EMBO J. 2017;36:751-760 pubmed publisher
	Siddiqui S, Schwarz F, Springer S, Khedri Z, Yu H, Deng L, et al. Studies on the Detection, Expression, Glycosylation, Dimerization, and Ligand Binding Properties of Mouse Siglec-E. J Biol Chem. 2017;292:1029-1037 pubmed publisher
	Roy S, Mandal C. Leishmania donovani Utilize Sialic Acids for Binding and Phagocytosis in the Macrophages through Selective Utilization of Siglecs and Impair the Innate Immune Arm. PLoS Negl Trop Dis. 2016;10:e0004904 pubmed publisher

product information

master code :

AF5806

SKU :

AF5806

product name :

Mouse Siglec-E Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Siglec-E Antibody from R&D Systems is a goat polyclonal antibody to Siglec-E. This antibody reacts with hamster,human,mouse,primate - chlorocebus aethiops (african green monkey). The Mouse Siglec-E Antibody has been validated for the following applications: Immunocytochemistry,Immunoprecipitation,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry.

target :

Siglec-E

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Siglec-E, Gln20-Phe355, Accession # Q6PJ50

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Hamster,Human,Mouse,Primate - Chlorocebus aethiops (African Green Monkey)

specificity :

Detects mouse Siglec-E in direct ELISAs and Western blots. In direct ELISAs, less than 3% cross-reactivity with recombinant human (rh) Siglec-6, rhSiglec-7, and rhSiglec-9 is observed.

gene symbol :

Siglece

top caption :

Detection of Mouse Siglec-E antibody by Western Blot.

accessionNumbers :

Q6PJ50

applications :

Immunocytochemistry,Immunoprecipitation,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry

USD :

479 USD

alt names :

CD170;CD33L2;OBBP2;OB-BP2;Sialic acid-binding Ig-like lectin 5;SIGLEC5;SIGLEC-5, SiglecE

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage