Human BACH1 Antibody | R&D Systems AF5776 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human BACH1 Antibody

catalog :

AF5776

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, chromatin immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 7

Reference
He Y, Guo J, Yu Y, Jin J, Jiang Q, Li Q, et al. BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17. Cell Rep. 2023;42:113468 pubmed publisher
Xie X, Tian L, Zhao Y, Liu F, Dai S, Gu X, et al. BACH1-induced ferroptosis drives lymphatic metastasis by repressing the biosynthesis of monounsaturated fatty acids. Cell Death Dis. 2023;14:48 pubmed publisher
Padilla J, Lee B, Zhai K, Rentz B, Bobo T, Dowling N, et al. A Heme-Binding Transcription Factor BACH1 Regulates Lactate Catabolism Suggesting a Combined Therapy for Triple-Negative Breast Cancer. Cells. 2022;11: pubmed publisher
Zhao Y, Gao J, Xie X, Nan P, Liu F, Sun Y, et al. BACH1 promotes the progression of esophageal squamous cell carcinoma by inducing the epithelial-mesenchymal transition and angiogenesis. Cancer Med. 2021;10:3413-3426 pubmed publisher
Xu J, Guo H, Xing Z, Zhang W, He J, Cheng J, et al. Mild Oxidative Stress Reduces NRF2 SUMOylation to Promote Kras/Lkb1/Keap1 Mutant Lung Adenocarcinoma Cell Migration and Invasion. Oxid Med Cell Longev. 2020;2020:6240125 pubmed publisher
Wei X, Guo J, Li Q, Jia Q, Jing Q, Li Y, et al. Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells. Sci Adv. 2019;5:eaau7887 pubmed publisher
Lee J, Yesilkanal A, Wynne J, Frankenberger C, Liu J, Yan J, et al. Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. Nature. 2019;568:254-258 pubmed publisher

product information

master code :

AF5776

SKU :

AF5776

product name :

Human BACH1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human BACH1 Antibody from R&D Systems is a goat polyclonal antibody to BACH1. This antibody reacts with human. The Human BACH1 Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Chromatin Immunoprecipitation (ChIP),Immunohistochemistry.

target :

BACH1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human BACH1, Ser133-Glu513, Accession # O14867

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human BACH1 in Western blots.

gene symbol :

BACH1

top caption :

Detection of Human BACH1 antibody by Western Blot.

accessionNumbers :

O14867

applications :

Immunoprecipitation,Western Blot,Chromatin Immunoprecipitation (ChIP),Immunohistochemistry

USD :

469 USD

alt names :

basic region leucine zipper transcriptional regulator BACH1, BTB, BTB and CNC homolog 1, BTB and CNC homology 1, basic leucine zipper transcription factor 1, HA2303, transcription regulator protein BACH1, transcription regulator protein10BACH-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage