product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse/Rat Neuropilin-2 Antibody
catalog :
AF567
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; fig 2b
Dieterich L, Tacconi C, Menzi F, Proulx S, Kapaklikaya K, Hamada M, et al. Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis. Angiogenesis. 2020;23:411-423 pubmed publisher
Murphy K, Duncan B, Sperringer J, Zhang E, Haberman V, Wyatt E, et al. Ankyrin B Promotes Developmental Spine Regulation in the Mouse Prefrontal Cortex. bioRxiv. 2023;: pubmed publisher
Chiang I, Graus M, Kirschnick N, Davidson T, Luu W, Harwood R, et al. The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner. EMBO J. 2023;42:e109032 pubmed publisher
Lin J, Mitchell T, Rothstein M, Pehl A, Taroc E, Katreddi R, et al. Sociosexual behavior requires both activating and repressive roles of Tfap2e/AP-2ε in vomeronasal sensory neurons. elife. 2022;11: pubmed publisher
Zhang Y, Orts xe4 ter H, Martínez Corral I, M xe4 kinen T. Cdh5-lineage-independent origin of dermal lymphatics shown by temporally restricted lineage tracing. Life Sci Alliance. 2022;5: pubmed publisher
Bahreini Jangjoo S, Lin J, Etaati F, Fearnley S, Cloutier J, Khmaladze A, et al. Automated quantification of vomeronasal glomeruli number, size, and color composition after immunofluorescent staining. Chem Senses. 2021;46: pubmed publisher
Paulson D, Harms R, Ward C, Latterell M, Pazour G, Fink D. Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation. Front Cell Dev Biol. 2021;9:672625 pubmed publisher
Ma W, Gil H, Liu X, Diebold L, Morgan M, Oxendine Burns M, et al. Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance. Sci Adv. 2021;7: pubmed publisher
Takano T, Wallace J, Baldwin K, Purkey A, Uezu A, Courtland J, et al. Chemico-genetic discovery of astrocytic control of inhibition in vivo. Nature. 2020;588:296-302 pubmed publisher
Geng X, Yanagida K, Akwii R, Choi D, Chen L, Ho Y, et al. S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020;5: pubmed publisher
Naik A, Lin J, Taroc E, Katreddi R, Frias J, Lemus A, et al. Smad4-dependent morphogenic signals control the maturation and axonal targeting of basal vomeronasal sensory neurons to the accessory olfactory bulb. Development. 2020;147: pubmed publisher
Yoo H, Lee Y, Park C, Son D, Choi D, Park J, et al. Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function. Cell Death Dis. 2020;11:14 pubmed publisher
xc1 lvarez Aznar A, Mart xed nez Corral I, Daubel N, Betsholtz C, M xe4 kinen T, Gaengel K. Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreERT2 lines. Transgenic Res. 2020;29:53-68 pubmed publisher
Overman J, Fontaine F, Wylie Sears J, Moustaqil M, Huang L, Meurer M, et al. R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma. elife. 2019;8: pubmed publisher
Mohan V, Wade S, Sullivan C, Kasten M, Sweetman C, Stewart R, et al. Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B. J Neurosci. 2019;39:6233-6250 pubmed publisher
Stone O, Stainier D. Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium. Dev Cell. 2019;: pubmed publisher
Murakami Y, Naganuma H, Tanigawa S, Fujimori T, Eto M, Nishinakamura R. Reconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation. Sci Rep. 2019;9:1172 pubmed publisher
LEE P, Gao N, Dike M, Shkilnyy O, Me R, Zhang Y, et al. Opposing Effects of Neuropilin-1 and -2 on Sensory Nerve Regeneration in Wounded Corneas: Role of Sema3C in Ameliorating Diabetic Neurotrophic Keratopathy. Diabetes. 2019;68:807-818 pubmed publisher
Frye M, Taddei A, Dierkes C, Martínez Corral I, Fielden M, Ortsäter H, et al. Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program. Nat Commun. 2018;9:1511 pubmed publisher
Tatin F, Renaud Gabardos E, Godet A, Hantelys F, Pujol F, Morfoisse F, et al. Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction. JCI Insight. 2017;2: pubmed publisher
Kunath J, Delaroque N, Szardenings M, Neundorf I, Straub R. Sympathetic nerve repulsion inhibited by designer molecules in vitro and role in experimental arthritis. Life Sci. 2017;168:47-53 pubmed publisher
Cha B, Geng X, Mahamud M, Fu J, Mukherjee A, Kim Y, et al. Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016;30:1454-69 pubmed publisher
Ulvmar M, Martínez Corral I, Stanczuk L, Makinen T. Pdgfrb-Cre targets lymphatic endothelial cells of both venous and non-venous origins. Genesis. 2016;54:350-8 pubmed publisher
product information
master code :
AF567
SKU :
AF567
product name :
Mouse/Rat Neuropilin-2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse/Rat Neuropilin-2 Antibody from R&D Systems is a goat polyclonal antibody to Neuropilin-2. This antibody reacts with mouse,rat,transgenic mouse. The Mouse/Rat Neuropilin-2 Antibody has been validated for the following applications: Immunohistochemistry,Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western,Blockade of Receptor-ligand Interaction.
target :
Neuropilin-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant rat Neuropilin-2, Gln23-Asp857 (Val809-Asp825 del), Accession # O35276
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Rat,Transgenic Mouse
specificity :
Detects mouse and rat Neuropilin-2 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human Neuropilin-2 and recombinant rat Neuropilin-1 is observed.
gene symbol :
NRP2
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Mouse and Rat Neuropilin-2 antibody by Western Blot.
accessionNumbers :
O35276
applications :
Immunohistochemistry,Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western,Blockade of Receptor-ligand Interaction
USD :
519 USD
alt names :
MGC126574, neuropilin 2, neuropilin-2, Neuropilin2, neuropilin-2a(22), neuropilin-2b(0), NP2, NPN 2, NPN2, PRO2714, receptor for VEGF165 and semaphorins class3, Vascular endothelial cell growth factor 165 receptor 2, vascular endothelial growth factor-165 receptor 2, VEGF1265R2, VEGF165R2neuropilin-2a(17)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.