Mouse Complement Factor D/Adipsin Antibody | R&D Systems AF5430 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Complement Factor D/Adipsin Antibody

catalog :

AF5430

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 11

Reference
He Y, Zhang R, Yu L, Zahr T, Li X, Kim T, et al. PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction. Cells. 2023;12: pubmed publisher
Wan Q, Calhoun C, Zahr T, Qiang L. Uncoupling Lipid Synthesis from Adipocyte Development. Biomedicines. 2023;11: pubmed publisher
Aaron N, Zahr T, He Y, Yu L, Mayfield B, Pajvani U, et al. Acetylation of PPARγ in macrophages promotes visceral fat degeneration in obesity. Life Metab. 2022;1:258-269 pubmed publisher
Wan Q, Huang B, Li T, Xiao Y, He Y, Du W, et al. Selective targeting of visceral adiposity by polycation nanomedicine. Nat Nanotechnol. 2022;17:1311-1321 pubmed publisher
He Y, B nai Taub A, Yu L, Yao Y, Zhang R, Zahr T, et al. PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms. Adv Sci (Weinh). 2022;:e2204190 pubmed publisher
Choi C, Barr W, Zaman S, Model C, Park A, Koenen M, et al. LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation. elife. 2022;11: pubmed publisher
Mizuno M, Khaledian B, Maeda M, Hayashi T, Mizuno S, Munetsuna E, et al. Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction. Cancers (Basel). 2021;13: pubmed publisher
Aaron N, Kraakman M, Zhou Q, Liu Q, Costa S, Yang J, et al. Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells. elife. 2021;10: pubmed publisher
Pauly D, Agarwal D, Dana N, Schäfer N, Biber J, Wunderlich K, et al. Cell-Type-Specific Complement Expression in the Healthy and Diseased Retina. Cell Rep. 2019;29:2835-2848.e4 pubmed publisher
Wu X, Hutson I, Akk A, Mascharak S, Pham C, Hourcade D, et al. Contribution of Adipose-Derived Factor D/Adipsin to Complement Alternative Pathway Activation: Lessons from Lipodystrophy. J Immunol. 2018;200:2786-2797 pubmed publisher
Williams J, Stampoulis D, Gunter C, Greenwood J, Adamson P, Moss S. Regulation of C3 Activation by the Alternative Complement Pathway in the Mouse Retina. PLoS ONE. 2016;11:e0161898 pubmed publisher

product information

master code :

AF5430

SKU :

AF5430

product name :

Mouse Complement Factor D/Adipsin Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Complement Factor D/Adipsin Antibody from R&D Systems is a sheep polyclonal antibody to Complement Factor D/Adipsin. This antibody reacts with mouse. The Mouse Complement Factor D/Adipsin Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunoprecipitation.

target :

Complement Factor D/Adipsin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Sheep

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Complement Factor D/Adipsin, Ile26-Ser259, Accession # P03953

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse

specificity :

Detects mouse Complement Factor D/Adipsin in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human (rh) Complement Factor D is observed and less than 5% cross-reactivity with rhGranzyme A is observed.

gene symbol :

CFD

top caption :

Detection of Mouse Complement Factor D/Adipsin antibody by Western Blot.

accessionNumbers :

P03953

applications :

Western Blot,Immunohistochemistry,Immunoprecipitation

USD :

459 USD

alt names :

Adipsin, ADN, ADNcomplement factor D, AMBP-1, C3 convertase activator, CFD, complement factor D (adipsin), complement factor D preproprotein, D component of complement (adipsin), DF, EC 3.4.21, EC 3.4.21.46, PFD, Properdin factor DADIPSIN

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage