Human/Mouse/Rat MuRF1/TRIM63 Antibody | R&D Systems AF5366 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat MuRF1/TRIM63 Antibody

catalog :

AF5366

quantity :

100 ug (also 25 ug)

price :

519 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

more info or order :

R&D Systems product webpage

citations: 15

Reference
Stouth D, vanLieshout T, Mikhail A, Ng S, Raziee R, Edgett B, et al. CARM1 drives mitophagy and autophagy flux during fasting-induced skeletal muscle atrophy. Autophagy. 2024;20:1247-1269 pubmed publisher
Sinha S, Alluri K, Somepalli V, Golakoti T, Sengupta K. A synergistic blend of Garcinia mangostana fruit rind and Cinnamomum tamala leaf extracts enhances myogenic differentiation and mitochondrial biogenesis in vitro and muscle growth and strength in mice. Food Nutr Res. 2023;67: pubmed publisher
Rudar M, Naberhuis J, Suryawan A, Nguyen H, Fiorotto M, Davis T. Prematurity blunts protein synthesis in skeletal muscle independently of body weight in neonatal pigs. Pediatr Res. 2023;94:143-152 pubmed publisher
Suh D, Lee W, Yeo W, Kyung B, Jung K, Seo H, et al. A Novel Muscle Atrophy Mechanism: Myocyte Degeneration Due to Intracellular Iron Deprivation. Cells. 2022;11: pubmed publisher
Jee H, Park E, Hur K, Kang M, Kim Y. High-Intensity Aerobic Exercise Suppresses Cancer Growth by Regulating Skeletal Muscle-Derived Oncogenes and Tumor Suppressors. Front Mol Biosci. 2022;9:818470 pubmed publisher
Rudar M, Naberhuis J, Suryawan A, Nguyen H, Stoll B, Style C, et al. Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model. Am J Physiol Endocrinol Metab. 2021;321:E737-E752 pubmed publisher
Parveen A, Bohnert K, Tomaz da Silva M, Wen Y, Bhat R, Roy A, et al. MyD88-mediated signaling intercedes in neurogenic muscle atrophy through multiple mechanisms. FASEB J. 2021;35:e21821 pubmed publisher
Campelj D, Timpani C, Petersen A, Hayes A, Goodman C, Rybalka E. The Paradoxical Effect of PARP Inhibitor BGP-15 on Irinotecan-Induced Cachexia and Skeletal Muscle Dysfunction. Cancers (Basel). 2020;12: pubmed publisher
Liu L, Killoy K, Vargas M, Yamamoto Y, Pehar M. Effects of RAGE inhibition on the progression of the disease in hSOD1G93A ALS mice. Pharmacol Res Perspect. 2020;8:e00636 pubmed publisher
Noguchi M, Kitakaze T, Kobayashi Y, Mukai K, Harada N, Yamaji R. β-Cryptoxanthin Improves p62 Accumulation and Muscle Atrophy in the Soleus Muscle of Senescence-Accelerated Mouse-Prone 1 Mice. Nutrients. 2020;12: pubmed publisher
Xia P, Chen J, Liu Y, Fletcher M, Jensen B, Cheng Z. Doxorubicin induces cardiomyocyte apoptosis and atrophy through cyclin-dependent kinase 2-mediated activation of forkhead box O1. J Biol Chem. 2020;295:4265-4276 pubmed publisher
Akkad H, Cacciani N, Llano Diez M, Corpeno Kalamgi R, Tchkonia T, Kirkland J, et al. Vamorolone treatment improves skeletal muscle outcome in a critical illness myopathy rat model. Acta Physiol (Oxf). 2019;225:e13172 pubmed publisher
Zhou L, Huang Y, Xie H, Mei X. Buyang Huanwu Tang improves denervation-dependent muscle atrophy by increasing ANGPTL4, and increases NF-?B and MURF1 levels. Mol Med Rep. 2018;17:3674-3680 pubmed publisher
Shimizu H, Langenbacher A, Huang J, Wang K, Otto G, Geisler R, et al. The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes. elife. 2017;6: pubmed publisher
Hirunsai M, Yimlamai T, Suksamrarn A. Effect of 20-Hydroxyecdysone on Proteolytic Regulation in Skeletal Muscle Atrophy. In Vivo. 2016;30:869-877 pubmed

product information

master code :

AF5366

SKU :

AF5366

product name :

Human/Mouse/Rat MuRF1/TRIM63 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat MuRF1/TRIM63 Antibody from R&D Systems is a goat polyclonal antibody to MuRF1/TRIM63. This antibody reacts with human,mouse,porcine,rat,fish - danio rerio (zebrafish). The Human/Mouse/Rat MuRF1/TRIM63 Antibody has been validated for the following applications: Western Blot,Simple Western.

target :

MuRF1/TRIM63

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human MuRF1/TRIM63, Met1-Gly325, Accession # Q969Q1

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Porcine,Rat,Fish - Danio rerio (Zebrafish)

specificity :

Detects human, mouse, and rat MuRF1/TRIM63 in direct ELISAs and Western blots.

gene symbol :

TRIM63

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human/Mouse/Rat MuRF1 antibody by Western Blot.

accessionNumbers :

Q969Q1

applications :

Western Blot,Simple Western

USD :

519 USD

alt names :

EC 6.3.2.-, IRF, IRFMURF2, Iris RING finger protein, MuRF1, MuRF-1, muscle specific ring finger protein 2, Muscle-specific RING finger protein 1, RING finger protein 28FLJ32380, RNF28, RNF28E3 ubiquitin-protein ligase TRIM63, SMRZ, SMRZMURF-1, Striated muscle RING zinc finger protein, TRIM63, tripartite motif containing 63, tripartite motif-containing 63, Tripartite motif-containing protein 63

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage