product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse Neuroplastin 65 Antibody
catalog :
AF5360
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 8
Reference
Cheng J, Chen L, Zheng Y, Liu J, Zhang L, Zhang X, et al. Disfunction of dorsal raphe nucleus-hippocampus serotonergic-HTR3 transmission results in anxiety phenotype of Neuroplastin 65-deficient mice. Acta Pharmacol Sin. 2024;45:1393-1405 pubmed publisher
Wu D, Cheng J, Zheng Y, Liu Y, Hou S, Liu L, et al. Neuroplastin 65 deficiency reduces amyloid plaque formation and cognitive deficits in an Alzheimer's disease mouse model. Front Cell Neurosci. 2023;17:1129773 pubmed publisher
Kershberg L, Banerjee A, Kaeser P. Protein composition of axonal dopamine release sites in the striatum. elife. 2022;11: pubmed publisher
Goodyer W, Beyersdorf B, Duan L, van den Berg N, Mantri S, Galdos F, et al. In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022;132: pubmed publisher
Newton S, Kong F, Carlton A, Aguilar C, Parker A, Codner G, et al. Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing. PLoS Genet. 2022;18:e1009937 pubmed publisher
Balog M, Bla x17e eti x107 S, Ivi x107 V, Labak I, Krajnik B, Marin R, et al. Disarranged neuroplastin environment upon aging and chronic stress recovery in female Sprague Dawley rats. Eur J Neurosci. 2022;55:2474-2490 pubmed publisher
Ilic K, Lin X, Malci A, Stojanovi x107 M, Puljko B, Ro x17e man M, et al. Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts. Int J Mol Sci. 2021;22: pubmed publisher
Zeng W, Grillet N, Dewey J, Trouillet A, Krey J, Barr Gillespie P, et al. Neuroplastin Isoform Np55 Is Expressed in the Stereocilia of Outer Hair Cells and Required for Normal Outer Hair Cell Function. J Neurosci. 2016;36:9201-16 pubmed publisher
product information
brand :
R&D Systems
master code :
AF5360
SKU :
AF5360
product name :
Human/Mouse Neuroplastin 65 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse Neuroplastin 65 Antibody from R&D Systems is a goat polyclonal antibody to Neuroplastin 65. This antibody reacts with human,mouse,rat,transgenic mouse. The Human/Mouse Neuroplastin 65 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
Neuroplastin 65
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Immunohistochemistry 5-15 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Neuroplastin 65, Gln29-His336, Accession # NP_036560
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse
specificity :
Detects human and mouse Neuroplastin 65 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human Neuroplastin 55 is observed.
gene symbol :
NPTN
top caption :
Neuroplastin 65 antibody in Human Brain by Immunohistochemistry (IHC-P).
accessionNumbers :
NP_036560
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
499 USD
alt names :
GP55;GP65;np55;np65;NPTN;SDFR1;SDR1, Np65
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.