Human SMPD1 Antibody | R&D Systems AF5348 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human SMPD1 Antibody

catalog :

AF5348

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 5

Reference
Suvarna K, Jayabal P, Ma X, Wang H, Chen Y, Weintraub S, et al. Ceramide-induced cleavage of GPR64 intracellular domain drives Ewing sarcoma. Cell Rep. 2024;43:114497 pubmed publisher
Wilson G, Patel S, Wang J, Xu K, Turner K, Becker K, et al. Acid sphingomyelinase expression is associated with survival in resectable pancreatic ductal adenocarcinoma. J Mol Med (Berl). 2023;101:891-903 pubmed publisher
Mohamud Yusuf A, Hagemann N, Zhang X, Zafar M, Hussner T, Bromkamp C, et al. Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles. Basic Res Cardiol. 2022;117:43 pubmed publisher
Ilnytska O, Lai K, Gorshkov K, Schultz M, Tran B, Jeziorek M, et al. Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage. J Biol Chem. 2021;297:100813 pubmed publisher
Xiong X, Lee C, Li W, Yu J, Zhu L, Kim Y, et al. Acid Sphingomyelinase regulates the localization and trafficking of palmitoylated proteins. Biol Open. 2019;: pubmed publisher

product information

master code :

AF5348

SKU :

AF5348

product name :

Human SMPD1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human SMPD1 Antibody from R&D Systems is a goat polyclonal antibody to SMPD1. This antibody reacts with human. The Human SMPD1 Antibody has been validated for the following applications: Immunocytochemistry,Western Blot,Simple Western.

target :

SMPD1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human SMPD1, His62-Pro628, Accession # NP_000534

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human SMPD1 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant mouse SMPD1 is observed.

gene symbol :

SMPD1

top caption :

Detection of Human SMPD1 antibody by Western Blot.

accessionNumbers :

NP_000534

applications :

Immunocytochemistry,Western Blot,Simple Western

USD :

459 USD

alt names :

Acid sphingomyelinase, ASMASE, ASMsphingomyelin phosphodiesterase, EC 3.1.4.12, NPD, sphingomyelin phosphodiesterase 1, acid lysosomal

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage