Human Plexin B2 Antibody | R&D Systems AF5329 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Plexin B2 Antibody

catalog :

AF5329

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Alves C, Hannah T, Sadia S, Kolsteeg C, Dixon A, Wiener R, et al. Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2. bioRxiv. 2024;: pubmed publisher
Garg R, Endzhievskaya S, Williamson M. B-type Plexins promote the GTPase activity of Ran to affect androgen receptor nuclear translocation in prostate cancer. Cancer Gene Ther. 2023;30:1513-1523 pubmed publisher
Karki A, Purohit R, Nosack S, Bharathy N, Michalek J, Chen S, et al. Plexin-B2 and Semaphorins Do Not Drive Rhabdomyosarcoma Proliferation or Migration. Sarcoma. 2022;2022:9646909 pubmed publisher
Junqueira Alves C, Dariolli R, Haydak J, Kang S, Hannah T, Wiener R, et al. Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion. Nat Commun. 2021;12:6019 pubmed publisher
Jiang C, Javed A, Kaiser L, Nava M, Xu R, Brandt D, et al. Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021;12:1308 pubmed publisher
Huang Y, Tejero R, Lee V, Brusco C, Hannah T, Bertucci T, et al. Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics. Commun Biol. 2021;4:145 pubmed publisher
Zuazo Gaztelu I, Pàez Ribes M, Carrasco P, Martin L, Soler A, Martínez Lozano M, et al. Antitumor Effects of Anti-Semaphorin 4D Antibody Unravel a Novel Proinvasive Mechanism of Vascular-Targeting Agents. Cancer Res. 2019;79:5328-5341 pubmed publisher
McColl B, Garg R, Riou P, Riento K, Ridley A. Rnd3-induced cell rounding requires interaction with Plexin-B2. J Cell Sci. 2016;129:4046-4056 pubmed

product information

master code :

AF5329

SKU :

AF5329

product name :

Human Plexin B2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Plexin B2 Antibody from R&D Systems is a sheep polyclonal antibody to Plexin B2. This antibody reacts with human,mouse. The Human Plexin B2 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunocytochemistry,Knockout Validated.

target :

Plexin B2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Sheep

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human Plexin B2, Leu20-Arg1160, Accession # O15031

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human Plexin B2 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant mouse Plexin B2 is observed.

gene symbol :

PLXNB2

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human Plexin B2 antibody by Western Blot.

accessionNumbers :

O15031

applications :

Western Blot,Immunohistochemistry,Immunocytochemistry,Knockout Validated

USD :

489 USD

alt names :

MM1, MM1KIAA0315dJ402G11.3, Nbla00445, PLEXB2, plexin B2, plexin-B2, PLXNB2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage