product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse TGF┐▀ RII Antibody
catalog :
AF532
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:400; loading ...; fig s2
Lam J, van den Bosch M, Wegrzyn J, Parker J, Ibrahim R, Slowski K, et al. miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling. Nat Commun. 2018;9:2418 pubmed publisher
Zahraeifard S, Xiao Z, So J, Ahad A, Montoya S, Park W, et al. Loss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression. Nat Commun. 2024;15:5873 pubmed publisher
Lee J, Fra Bido S, Burton A, Innocentin S, Hill D, Linterman M. B cell-intrinsic changes with age do not impact antibody-secreting cell formation but delay B cell participation in the germinal centre reaction. Aging Cell. 2022;21:e13692 pubmed publisher
Rivellese F, Surace A, Goldmann K, Sciacca E, xc7 ubuk C, Giorli G, et al. Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial. Nat Med. 2022;28:1256-1268 pubmed publisher
Wanner N, Barnhart J, Apostolakis N, Zlojutro V, Asosingh K. Using the Autofluorescence Finder on the Sony ID7000TM Spectral Cell Analyzer to Identify and Unmix Multiple Highly Autofluorescent Murine Lung Populations. Front Bioeng Biotechnol. 2022;10:827987 pubmed publisher
Andreou T, Williams J, Brownlie R, Salmond R, Watson E, Shaw G, et al. Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model. J Immunother Cancer. 2021;9: pubmed publisher
Nolan K, Verzosa G, Cleaver T, Tippimanchai D, DePledge L, Wang X, et al. Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models. Cancer Cell Int. 2020;20:417 pubmed publisher
Fedeli M, Riba M, Garcia Manteiga J, Tian L, Viganò V, Rossetti G, et al. miR-17∼92 family clusters control iNKT cell ontogenesis via modulation of TGF-β signaling. Proc Natl Acad Sci U S A. 2016;113:E8286-E8295 pubmed publisher
Liu G, Bi Y, Xue L, Zhang Y, Yang H, Chen X, et al. Dendritic cell SIRT1-HIF1α axis programs the differentiation of CD4+ T cells through IL-12 and TGF-β1. Proc Natl Acad Sci U S A. 2015;112:E957-65 pubmed publisher
product information
master code :
AF532
SKU :
AF532
product name :
Mouse TGF┐▀ RII Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse TGF¿ß RII Antibody from R&D Systems is a goat polyclonal antibody to TGF-beta RII. This antibody reacts with mouse,transgenic mouse. The Mouse TGF¿ß RII Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Immunocytochemistry,CyTOF-ready.
target :
TGF-beta RII
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse TGF┐▀ RII and S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TGF┐▀ RII, Ile24-Asp184, Accession # Q62312
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Transgenic Mouse
specificity :
Detects mouse TGF┐▀ RII in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) TGF┐▀ RII is observed.
gene symbol :
TGFBR2
top caption :
Detection of Mouse TGF-ss RII antibody by Western Blot.
accessionNumbers :
Q62312
applications :
Western Blot,Flow Cytometry,Immunocytochemistry,CyTOF-ready
USD :
489 USD
alt names :
AAT3, EC 2.7.11, EC 2.7.11.30, FAA3, HNPCC6, LDS1B, LDS2B, MFS2, RIIC, TAAD2, tbetaR-II, TGF-beta receptor type II, TGF-beta receptor type IIB, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbetaRII, TGFbeta-RII, TGFBR2, TGF-bRII, TGFR-2, transforming growth factor beta receptor type IIC, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II (70/80kDa) isoform 1, transforming growth factor, beta receptor II (70/80kDa) isoform 2, transforming growth factor, beta receptor II (70-80kD), Transforming growth factor-beta receptor type II
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.