Mouse HGFR/c-MET Antibody | R&D Systems AF527 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse HGFR/c-MET Antibody

catalog :

AF527

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse	Weinstock A, RAHMAN K, Yaacov O, Nishi H, Menon P, Nikain C, et al. Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis. elife. 2021;10: pubmed publisher
	Rizzoti K, Chakravarty P, Sheridan D, Lovell Badge R. SOX9-positive pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on context. Sci Adv. 2023;9:eadf6911 pubmed publisher
	Gen xe7 B, Nho B, Seung H, Helmold B, Park H, G xf6 z xfc tok x, et al. Novel rAAV vector mediated intrathecal HGF delivery has an impact on neuroimmune modulation in the ALS motor cortex with TDP-43 pathology. Gene Ther. 2023;30:560-574 pubmed publisher
	Sefton E, Gallardo M, Tobin C, Collins B, Colasanto M, Merrell A, et al. Fibroblast-derived Hgf controls recruitment and expansion of muscle during morphogenesis of the mammalian diaphragm. elife. 2022;11: pubmed publisher
	Jiang A, Wang B, Wang S, Zhao K, Wu H, Yan K, et al. The study of direct and indirect effects of radiofrequency ablation on tumor microenvironment in liver tumor animal model. BMC Cancer. 2022;22:663 pubmed publisher
	Hedou E, Douceau S, Chevilley A, Varangot A, Thiebaut A, Triniac H, et al. Two-Chains Tissue Plasminogen Activator Unifies Met and NMDA Receptor Signalling to Control Neuronal Survival. Int J Mol Sci. 2021;22: pubmed publisher
	Kamitakahara A, Ali Marandi Ghoddousi R, Lanjewar A, Magalong V, Wu H, Levitt P. MET Receptor Tyrosine Kinase Regulates Lifespan Ultrasonic Vocalization and Vagal Motor Neuron Development. Front Neurosci. 2021;15:768577 pubmed publisher
	Aldahl J, Mi J, Pineda A, Kim W, Olson A, Hooker E, et al. Aberrant activation of hepatocyte growth factor/MET signaling promotes β-catenin-mediated prostatic tumorigenesis. J Biol Chem. 2020;295:631-644 pubmed publisher
	Mi J, Hooker E, Balog S, Zeng H, Johnson D, He Y, et al. Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate. J Biol Chem. 2018;293:20123-20136 pubmed publisher
	Kato K, Diéguez Hurtado R, Park D, Hong S, Kato Azuma S, Adams S, et al. Pulmonary pericytes regulate lung morphogenesis. Nat Commun. 2018;9:2448 pubmed publisher
	Shibata S, Miwa T, Wu H, Levitt P, Ohyama T. Hepatocyte Growth Factor-c-MET Signaling Mediates the Development of Nonsensory Structures of the Mammalian Cochlea and Hearing. J Neurosci. 2016;36:8200-9 pubmed publisher
	Barrow McGee R, Kishi N, Joffre C, Ménard L, Hervieu A, Bakhouche B, et al. Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes. Nat Commun. 2016;7:11942 pubmed publisher
	Tesfay L, Schulz V, Frank S, Lamb L, Miranti C. Receptor tyrosine kinase Met promotes cell survival via kinase-independent maintenance of integrin α3β1. Mol Biol Cell. 2016;27:2493-504 pubmed publisher

product information

brand :

R&D Systems

master code :

AF527

SKU :

AF527

product name :

Mouse HGFR/c-MET Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Mouse HGFR/c-MET Antibody from R&D Systems is a goat polyclonal antibody to HGFR/c-MET. This antibody reacts with human,mouse,rat. The Mouse HGFR/c-MET Antibody has been validated for the following applications: ELISA Development,ELISA Development (Capture),Flow Cytometry,Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Blockade of Receptor-ligand Interaction.

target :

HGFR/c-MET

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Blockade of Receptor-ligand Interaction, Immunocytochemistry 5-15 ug/mL

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse HGF R/c-MET, Glu25-Asn929, Accession # P16056

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects mouse HGF R/c-MET in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human (rh) HGF R and less than 1% cross-reactivity with rhMSP R is observed.

gene symbol :

MET

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

HGF R/c-MET antibody in HT-29 and U937 Human Cell Lines by Immunocytochemistry (ICC).

accessionNumbers :

P16056

applications :

Blockade of Receptor-ligand Interaction,ELISA Development,ELISA Development (Capture),Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry

USD :

499 USD

alt names :

AUTS9, c-Met, cMET, EC 2.7.10, EC 2.7.10.1, hepatocyte growth factor receptor, HGF R, HGF receptor, HGF/SF receptor, HGFR, MET, Met (c-Met), met proto-oncogene (hepatocyte growth factor receptor), met proto-oncogene tyrosine kinase, oncogene MET, Proto-oncogene c-Met, RCCP2, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage