Mouse Notch-1 Antibody | R&D Systems AF5267 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Notch-1 Antibody

catalog :

AF5267

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Nauman M, Varshney S, Choi J, Augenlicht L, Stanley P. EOGT enables residual Notch signaling in mouse intestinal cells lacking POFUT1. Sci Rep. 2023;13:17473 pubmed publisher
Matsumoto K, Kumar V, Varshney S, Nairn A, Ito A, Pennarubia F, et al. Fringe GlcNAc-transferases differentially extend O-fucose on endogenous NOTCH1 in mouse activated T cells. J Biol Chem. 2022;298:102064 pubmed publisher
Kakuda S, LoPilato R, Ito A, Haltiwanger R. Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2. J Biol Chem. 2020;295:14710-14722 pubmed publisher
Wiszniak S, Schwarz Q. Notch signalling defines dorsal root ganglia neuroglial fate choice during early neural crest cell migration. BMC Neurosci. 2019;20:21 pubmed publisher
Takeuchi H, Schneider M, Williamson D, Ito A, Takeuchi M, Handford P, et al. Two novel protein O-glucosyltransferases that modify sites distinct from POGLUT1 and affect Notch trafficking and signaling. Proc Natl Acad Sci U S A. 2018;115:E8395-E8402 pubmed publisher
Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, et al. Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017;8:578 pubmed publisher

product information

brand :

R&D Systems

master code :

AF5267

SKU :

AF5267

product name :

Mouse Notch-1 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Mouse Notch-1 Antibody from R&D Systems is a sheep polyclonal antibody to Notch-1. This antibody reacts with hamster,human,mouse. The Mouse Notch-1 Antibody has been validated for the following applications: IHC-F,Flow Cytometry,Western Blot,Immunohistochemistry.

target :

Notch-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 5-15 ug/mL

host :

Sheep

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant mouse Notch-1, Ala19-Gln526, Accession # AAM28905

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Hamster,Human,Mouse

specificity :

Detects mouse Notch-1 in direct ELISAs and Western blots. In direct ELISA, approximately 10% cross-reactivity with recombinant human Notch-1 and recombinant rat Notch-1 is observed and less than 1% cross-reactivity with recombinant mouse (rm) Notch-2 and rmNotch-3 is observed.

gene symbol :

NOTCH1

top caption :

Detection of Mouse Notch-1 antibody by Western Blot.

accessionNumbers :

AAM28905

applications :

Immunohistochemistry,IHC-F,Flow Cytometry,Western Blot

USD :

489 USD

alt names :

EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, Notch1, TAN1, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage