Human ST2/IL-33R Antibody | R&D Systems AF523 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human ST2/IL-33R Antibody

catalog :

AF523

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 10

Reference
Bisen S, Verma S, Mukhopadhyay C, Singh N. A neutrophil elastase-generated mature form of IL-33 is a potent regulator of endothelial cell activation and proliferative retinopathy. Exp Mol Med. 2024;56:1703-1716 pubmed publisher
Lei W, Zhang F, Lin Y, Li M, Pan F, Sun K, et al. IL-33/ST2 axis of human amnion fibroblasts participates in inflammatory reactions at parturition. Mol Med. 2023;29:88 pubmed publisher
Stephenson K, Porte J, Kelly A, Wallace W, Huntington C, Overed Sayer C, et al. The IL-33:ST2 axis is unlikely to play a central fibrogenic role in idiopathic pulmonary fibrosis. Respir Res. 2023;24:89 pubmed publisher
Indralingam C, Gutierrez Gonzalez A, Johns S, Tsui T, Cannon D, Fuster M, et al. IL-33/ST2 receptor-dependent signaling in the development of pulmonary hypertension in Sugen/hypoxia mice. Physiol Rep. 2022;10:e15185 pubmed publisher
Perez F, Ruera C, Miculán E, Carasi P, Dubois Camacho K, Garbi L, et al. IL-33 Alarmin and Its Active Proinflammatory Fragments Are Released in Small Intestine in Celiac Disease. Front Immunol. 2020;11:581445 pubmed publisher
Yangngam S, Thongchot S, Pongpaibul A, Vaeteewoottacharn K, Pinlaor S, Thuwajit P, et al. High level of interleukin-33 in cancer cells and cancer-associated fibroblasts correlates with good prognosis and suppressed migration in cholangiocarcinoma. J Cancer. 2020;11:6571-6581 pubmed publisher
Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, et al. The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis. Oncogene. 2019;: pubmed publisher
Landskron G, De la Fuente López M, Dubois Camacho K, Díaz Jiménez D, Orellana Serradell O, Romero D, et al. Interleukin 33/ST2 Axis Components Are Associated to Desmoplasia, a Metastasis-Related Factor in Colorectal Cancer. Front Immunol. 2019;10:1394 pubmed publisher
Schaunaman N, Sánchez A, Dimasuay K, Pavelka N, Alam R, Martin R, et al. Interleukin 1 receptor like 1 (IL1RL1) promotes airway bacterial and viral infection and inflammation. Infect Immun. 2019;: pubmed publisher
Ryu W, Lee H, Bae H, Jeon J, Ryu H, Kim J, et al. IL-33 down-regulates CLDN1 expression through the ERK/STAT3 pathway in keratinocytes. J Dermatol Sci. 2018;90:313-322 pubmed publisher

product information

master code :

AF523

SKU :

AF523

product name :

Human ST2/IL-33R Antibody

unit size :

100 ug (also 25 ug)

description :

The Human ST2/IL-33R Antibody from R&D Systems is a goat polyclonal antibody to ST2/IL-33R. This antibody reacts with human,mouse. The Human ST2/IL-33R Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry,Neutralization,Cell Culture,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western.

target :

ST2/IL-33R

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human ST2/IL-33 R, Lys19-Phe328, Accession # BAA02233

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human ST2/IL-33 R in direct ELISAs and Western blots.

gene symbol :

IL1RL1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Human ST2/IL-33 R antibody by Western Blot.

accessionNumbers :

BAA02233

applications :

Immunoprecipitation,Western Blot,Immunohistochemistry,Neutralization,Cell Culture,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western

USD :

499 USD

alt names :

DER4, DER4ST2growth stimulation-expressed, FIT-1, IL-1 R4, IL1R4, IL-1R4, IL-1RL1, IL-33 R, IL33R, IL-33R, interleukin 1 receptor-like 1, interleukin 1 receptor-related protein, interleukin-1 receptor-like 1, Ly84, MGC32623, Protein ST2, ST2L, ST2V, T1, T1homolog of mouse growth stimulation-expressed

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage