Rat IL-18/IL-1F4 Antibody | R&D Systems AF521 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Rat IL-18/IL-1F4 Antibody

catalog :

AF521

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 4

Reference
Mavrogiannis E, Hagdorn Q, Bazioti V, Douwes J, van der Feen D, Oberdorf Maass S, et al. Pirfenidone ameliorates pulmonary arterial pressure and neointimal remodeling in experimental pulmonary arterial hypertension by suppressing NLRP3 inflammasome activation. Pulm Circ. 2022;12:e12101 pubmed publisher
Luo J, Chen J, Yang C, Tan J, Zhao J, Jiang N, et al. 6-Gingerol protects against cerebral ischemia/reperfusion injury by inhibiting NLRP3 inflammasome and apoptosis via TRPV1 / FAF1 complex dissociation-mediated autophagy. Int Immunopharmacol. 2021;100:108146 pubmed publisher
He Q, Li Z, Meng C, Wu J, Zhao Y, Zhao J. Parkin-Dependent Mitophagy is Required for the Inhibition of ATF4 on NLRP3 Inflammasome Activation in Cerebral Ischemia-Reperfusion Injury in Rats. Cells. 2019;8: pubmed publisher
Kuwahara Otani S, Maeda S, Kobayashi K, Minato Y, Tanaka K, Yamanishi K, et al. Interleukin-18 and its receptor are expressed in gonadotropin-releasing hormone neurons of mouse and rat forebrain. Neurosci Lett. 2017;650:33-37 pubmed publisher

product information

brand :

R&D Systems

master code :

AF521

SKU :

AF521

product name :

Rat IL-18/IL-1F4 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Rat IL-18/IL-1F4 Antibody from R&D Systems is a goat polyclonal antibody to IL-18/IL-1F4. This antibody reacts with rat. The Rat IL-18/IL-1F4 Antibody has been validated for the following applications: Western Blot,Binding Assay,ELISA Development,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin.

target :

IL-18/IL-1F4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Neutralization 1-3 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant rat IL-18/IL-1F4, His37-Ser194, Accession # P97636

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Rat

specificity :

Detects rat IL-18/IL-1F4 in direct ELISAs and Western blots. In Western blots, approximately 35% cross-reactivity with recombinant mouse IL-18 is observed and approximately 10% cross-reactivity with recombinant human IL-18 is observed.

gene symbol :

IL18

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

IFN-? Secretion Induced by IL-18/IL-1F4 and Neutralization by Rat IL-18/IL-1F4 Antibody.

accessionNumbers :

P97636

applications :

Binding Assay,ELISA Development,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Neutralization

USD :

489 USD

alt names :

Iboctadekin, IFN-gamma-inducing factor, IGIF, IGIFIL-1 gamma, IL18, IL-18MGC12320, IL-1F4, IL1F4iboctadekin, IL-1g, Interferon gamma-inducing factor, interleukin 18 (interferon-gamma-inducing factor), Interleukin-1 gamma, interleukin-18

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage