Mouse IL-34 Antibody | R&D Systems AF5195 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-34 Antibody

catalog :

AF5195

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 4a	Pons V, Lévesque P, Plante M, Rivest S. Conditional genetic deletion of CSF1 receptor in microglia ameliorates the physiopathology of Alzheimer's disease. Alzheimers Res Ther. 2021;13:8 pubmed publisher
	Wang G, Garcia V, Lee J, Yanum J, Lin J, Jiang H, et al. Nrf2 deficiency causes hepatocyte dedifferentiation and reduced albumin production in an experimental extrahepatic cholestasis model. PLoS ONE. 2022;17:e0269383 pubmed publisher
	Xu B, Lin X, Gong Y, Lai X, Ren L, Cao J. Interleukin-34: an important modifier in the pathogenesis of influenza pneumonia. Crit Care. 2021;25:274 pubmed publisher
	Wada Y, Iyoda M, Matsumoto K, Suzuki T, Tachibana S, Kanazawa N, et al. Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice. PLoS ONE. 2021;16:e0245340 pubmed publisher
	Obst J, Simon E, Martín Estebané M, Pipi E, Barkwill L, Gonzalez Rivera I, et al. Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration. Front Immunol. 2020;11:579000 pubmed publisher
	Badimon A, Strasburger H, Ayata P, Chen X, Nair A, Ikegami A, et al. Negative feedback control of neuronal activity by microglia. Nature. 2020;: pubmed publisher
	Bonnardel J, T Jonck W, Gaublomme D, Browaeys R, Scott C, Martens L, et al. Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche. Immunity. 2019;51:638-654.e9 pubmed publisher
	Wada Y, Gonzalez Sanchez H, Weinmann Menke J, Iwata Y, Ajay A, Meineck M, et al. IL-34-Dependent Intrarenal and Systemic Mechanisms Promote Lupus Nephritis in MRL-Faslpr Mice. J Am Soc Nephrol. 2019;30:244-259 pubmed publisher
	Ogawa S, Matsuoka Y, Takada M, Matsui K, Yamane F, Kubota E, et al. Interleukin 34 (IL-34) cell-surface localization regulated by the molecular chaperone 78-kDa glucose-regulated protein facilitates the differentiation of monocytic cells. J Biol Chem. 2019;294:2386-2396 pubmed publisher

product information

master code :

AF5195

SKU :

AF5195

product name :

Mouse IL-34 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse IL-34 Antibody from R&D Systems is a sheep polyclonal antibody to IL-34. This antibody reacts with mouse. The Mouse IL-34 Antibody has been validated for the following applications: ELISA Capture,Neutralization,Bioassay,Flow Cytometry,Western Blot,Immunohistochemistry.

target :

IL-34

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Sheep

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse IL-34, Asn21-Pro235, Accession # Q8R1R4

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse

specificity :

Detects mouse IL-34 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human IL-34 is observed.

gene symbol :

Il34

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Mouse IL-34 antibody by Western Blot.

accessionNumbers :

Q8R1R4

applications :

Bioassay,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry

USD :

489 USD

alt names :

C16orf77, IL34, IL-34, interleukin 34

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage