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company name :
R&D Systems
product type :
antibody
product name :
Mouse/Rat IL-10 Antibody
catalog :
AF519
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 22
Reference
Liu H, Zhang L, Liu Z, Lin J, He X, Wu S, et al. Galectin-3 as TREM2 upstream factor contributes to lung ischemia-reperfusion injury by regulating macrophage polarization. iScience. 2023;26:107496 pubmed publisher
Komori T, Morikawa Y. Essential roles of the cytokine oncostatin M in crosstalk between muscle fibers and immune cells in skeletal muscle after aerobic exercise. J Biol Chem. 2022;298:102686 pubmed publisher
Runge E, Setter D, Iyer A, Regele E, Kennedy F, Sanders V, et al. Cellular Sources and Neuroprotective Roles of Interleukin-10 in the Facial Motor Nucleus after Axotomy. Cells. 2022;11: pubmed publisher
Park G, Tarafder S, Eyen S, Park S, Kim R, Siddiqui Z, et al. Oxo-M and 4-PPBP Delivery via Multi-Domain Peptide Hydrogel Toward Tendon Regeneration. Front Bioeng Biotechnol. 2022;10:773004 pubmed publisher
Cai B, Ma M, Zhang J, Wang Z, Kong S, Zhou Z, et al. LncEDCH1 improves mitochondrial function to reduce muscle atrophy by interacting with SERCA2. Mol Ther Nucleic Acids. 2022;27:319-334 pubmed publisher
Zhang D, Chen Q, Bi Y, Zhang H, Chen M, Wan J, et al. Bio-inspired poly-DL-serine materials resist the foreign-body response. Nat Commun. 2021;12:5327 pubmed publisher
Yergoz F, Friebel J, Krankel N, Rauch Kroehnert U, Schultheiss H, Landmesser U, et al. Adenine Nucleotide Translocase 1 Expression Modulates the Immune Response in Ischemic Hearts. Cells. 2021;10: pubmed publisher
Bao Z, Liu Y, Chen B, Miao Z, Tu Y, Li C, et al. Prokineticin-2 prevents neuronal cell deaths in a model of traumatic brain injury. Nat Commun. 2021;12:4220 pubmed publisher
Luo Y, Wang B, Liu J, Ma F, Luo D, Zheng Z, et al. Ginsenoside RG1 enhances the paracrine effects of bone marrow-derived mesenchymal stem cells on radiation induced intestinal injury. Aging (Albany NY). 2020;13:1132-1152 pubmed publisher
Wilkerson J, Alberti L, Kerwin A, Ledent C, Thakur G, Makriyannis A, et al. Peripheral versus central mechanisms of the cannabinoid type 2 receptor agonist AM1710 in a mouse model of neuropathic pain. Brain Behav. 2020;10:e01850 pubmed publisher
Kuo C, Chen J, Lin L, Schmid Schonbein G, Chien S, Huang P, et al. Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance. Sci Rep. 2020;10:1725 pubmed publisher
Dai W, Sun J, Li C, Mao W, Huang Y, Zhao Z, et al. Involvement of Interleukin-10 in Analgesia of Electroacupuncture on Incision Pain. Evid Based Complement Alternat Med. 2019;2019:8413576 pubmed publisher
Zilberman Itskovich S, Abu Hamad R, Zarura R, Sova M, Hachmo Y, Stark M, et al. Human mesenchymal stromal cells ameliorate complement induced inflammatory cascade and improve renal functions in a rat model of ischemia-reperfusion induced acute kidney injury. PLoS ONE. 2019;14:e0222354 pubmed publisher
Mao X, Wu H, Tang X, Ali U, Liu H, Wang Y. Activation of GPR40 produces mechanical antiallodynia via the spinal glial interleukin-10/β-endorphin pathway. J Neuroinflammation. 2019;16:84 pubmed publisher
Fang E, Hou Y, Palikaras K, Adriaanse B, Kerr J, Yang B, et al. Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease. Nat Neurosci. 2019;22:401-412 pubmed publisher
Rosenzweig N, Dvir Szternfeld R, Tsitsou Kampeli A, Keren Shaul H, Ben Yehuda H, Weill Raynal P, et al. PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model. Nat Commun. 2019;10:465 pubmed publisher
Zhao Y, Pan Y, Tang M, Lin W. Blocking p38 Signaling Reduces the Activation of Pro-inflammatory Cytokines and the Phosphorylation of p38 in the Habenula and Reverses Depressive-Like Behaviors Induced by Neuroinflammation. Front Pharmacol. 2018;9:511 pubmed publisher
Wu H, Tang X, Mao X, Wang Y. Autocrine Interleukin-10 Mediates Glucagon-Like Peptide-1 Receptor-Induced Spinal Microglial β-Endorphin Expression. J Neurosci. 2017;37:11701-11714 pubmed publisher
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product information
master code :
AF519
SKU :
AF519
product name :
Mouse/Rat IL-10 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse/Rat IL-10 Antibody from R&D Systems is a goat polyclonal antibody to IL-10. This antibody reacts with mouse,rat. The Mouse/Rat IL-10 Antibody has been validated for the following applications: Immunohistochemistry,Fluorescence Microscopy,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry.
target :
IL-10
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant rat IL-10, Ser19-Asn178, Accession # P29456
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Rat
specificity :
Detects mouse, rat, and cotton rat IL-10 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human IL-10, recombinant guinea pig IL-10, recombinant viral IL-10 and recombinant canine IL-10 is observed.
gene symbol :
IL10
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Recombinant Mouse and Rat IL-10 antibody by Western Blot.
accessionNumbers :
P29456
applications :
Immunohistochemistry,Fluorescence Microscopy,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry
USD :
509 USD
alt names :
CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.