product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Primate MMP-3 Antibody
catalog :
AF513
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 6
Reference
Muhammad K, Xavier D, Klein Hessling S, Azeem M, Rauschenberger T, Murti K, et al. NFAT5 Controls the Integrity of Epidermis. Front Immunol. 2021;12:780727 pubmed publisher
Liu S, Hu Y, Wang Y, Sun Y, Qin S, Xu D. Endosulfan promotes cell proliferation and extracellular matrix accumulation through TGF-β/Smad signaling pathway in HRMCs. Ecotoxicol Environ Saf. 2021;228:113040 pubmed publisher
Inamoto Y, Martin P, Onstad L, Cheng G, Williams K, Pusic I, et al. Relevance of Plasma Matrix Metalloproteinase-9 for Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplantation. Transplant Cell Ther. 2021;27:759.e1-759.e8 pubmed publisher
Muñoz D, Yannone S, Daemen A, Sun Y, Vakar Lopez F, Kawahara M, et al. Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging. JCI Insight. 2019;5: pubmed publisher
Kour S, Garimella M, Shiroor D, Mhaske S, Joshi S, Singh K, et al. IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice. J Immunol. 2016;196:5024-35 pubmed publisher
Beltrami Moreira M, Vromman A, Sukhova G, Folco E, Libby P. Redundancy of IL-1 Isoform Signaling and Its Implications for Arterial Remodeling. PLoS ONE. 2016;11:e0152474 pubmed publisher
product information
brand :
R&D Systems
master code :
AF513
SKU :
AF513
product name :
Human/Primate MMP-3 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Primate MMP-3 Antibody from R&D Systems is a goat polyclonal antibody to MMP-3. This antibody reacts with human,mouse,primate. The Human/Primate MMP-3 Antibody has been validated for the following applications: Immunohistochemistry,ELISA Development,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoprecipitation,ELISA Capture (Matched Antibody Pair).
target :
MMP-3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 2 ug/mL, Immunohistochemistry 5-15 ug/mL, Immunoprecipitation 25 ug/mL, ELISA Capture (Matched Antibody Pair) 0.2-0.8 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human MMP-3, Tyr18-Cys477 (Lys45Glu), Accession # P08254
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Primate
specificity :
Detects human and primate MMP-3 in ELISAs and Western blots. In sandwich ELISAs, less than 2.5% cross-reactivity with recombinant human (rh) MMP-10 is observed and less than 0.1% cross-reactivity with rhMMP-1, -2, -7, -8, -9, -12, -13, and recombinant mouse MMP-9 is observed.
gene symbol :
MMP3
top caption :
Detection of Human MMP-3 antibody by Western Blot.
accessionNumbers :
P08254
applications :
Immunoprecipitation,ELISA Capture (Matched Antibody Pair),ELISA Development,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
USD :
489 USD
alt names :
CHDS6, EC 3.4.24, EC 3.4.24.17, matrix metallopeptidase 3 (stromelysin 1, progelatinase), matrix metalloproteinase 3 (stromelysin 1, progelatinase), Matrix metalloproteinase-3, MGC126102, MGC126103, MMP3, MMP-3, proteoglycanase, SL-1, STMY, STMY1MGC126104, STR1, Stromelysin 1, stromelysin-1, Transin-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.