product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human EMR2 Antibody
catalog :
AF4894
quantity :
100 ug (also 25 ug)
price :
459 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human
application :
western blot, neutralization, immunoprecipitation
more info or order :
citations: 3
Reference
Irmscher S, Zipfel S, Halder L, Ivanov L, González Delgado A, Waldeyer C, et al. Factor H-related protein 1 (FHR-1) is associated with atherosclerotic cardiovascular disease. Sci Rep. 2021;11:22511 pubmed publisher
Bhudia N, Desai S, King N, Ancellin N, Grillot D, Barnes A, et al. G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody. Sci Rep. 2020;10:1004 pubmed publisher
Irmscher S, Brix S, Zipfel S, Halder L, Mutlutürk S, Wulf S, et al. Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies. Nat Commun. 2019;10:2961 pubmed publisher
product information
master code :
AF4894
SKU :
AF4894
product name :
Human EMR2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human EMR2 Antibody from R&D Systems is a sheep polyclonal antibody to EMR2. This antibody reacts with human. The Human EMR2 Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Neutralization.
target :
EMR2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Sheep
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human EMR2, Gln24-Gln478 (Gln24 predicted), Accession # NP_038475
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human EMR2 in direct ELISAs and Western blots. In direct ELISAs, this antibody shows less than 1% cross-reactivity with recombinant mouse EMR1.
gene symbol :
EMR2
top caption :
Cell Adhesion Mediated by EMR2 and Neutralization by Human EMR2 Antibody.
accessionNumbers :
NP_038475
applications :
Immunoprecipitation,Western Blot,Neutralization
USD :
459 USD
alt names :
CD312, DKFZp781B135, egf-like module containing, mucin-like, hormone receptor-like 2, egf-like module containing, mucin-like, hormone receptor-like sequence 2, EGF-like module receptor 2, EGF-like module-containing mucin-like hormone receptor-like 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.