product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat Vang-like Protein 2/VANGL2 Antibody
catalog :
AF4815
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 4a
Ban Y, Yu T, Feng B, Lorenz C, Wang X, Baker C, et al. Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex. Sci Adv. 2021;7:eabh2974 pubmed publisher
  • western blot; mouse; 1:100; loading ...; fig s9d
Wang Y, Baeyens N, Corti F, Tanaka K, Fang J, Zhang J, et al. Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development. Development. 2016;143:4441-4451 pubmed
  • immunohistochemistry - paraffin section; rat; 1:100; fig 1
Chen H, Mruk D, Lee W, Cheng C. Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats. Endocrinology. 2016;157:2140-59 pubmed publisher
Knapp L, Sun H, Wang Y, Chen B, Lin X, Gao N, et al. Rab11a Is Essential for the Development and Integrity of the Stereocilia and Kinocilia in the Mammalian Organ of Corti. Eneuro. 2023;10: pubmed publisher
Xie Z, Bankaitis V. Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration. Cell Rep. 2022;39:110869 pubmed publisher
Chen B, Qian X, Yang X, Jiang T, Wang Y, Lyu J, et al. Rab11a Regulates the Development of Cilia and Establishment of Planar Cell Polarity in Mammalian Vestibular Hair Cells. Front Mol Neurosci. 2021;14:762916 pubmed publisher
Wilson D, Jarman E, Mellin R, Wilson M, Waddell S, Tsokkou P, et al. Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors. Nat Commun. 2020;11:445 pubmed publisher
Cheng X, Song L, Lan M, Shi B, Li J. Morphological and molecular comparisons between tibialis anterior muscle and levator veli palatini muscle: A preliminary study on their augmentation potential. Exp Ther Med. 2018;15:247-253 pubmed publisher
Luo W, Yi H, Taylor J, Li J, Chi F, Todd N, et al. Cilia distribution and polarity in the epithelial lining of the mouse middle ear cavity. Sci Rep. 2017;7:45870 pubmed publisher
Dyberg C, Papachristou P, Haug B, Lagercrantz H, Kogner P, Ringstedt T, et al. Planar cell polarity gene expression correlates with tumor cell viability and prognostic outcome in neuroblastoma. BMC Cancer. 2016;16:259 pubmed publisher
product information
master code :
AF4815
SKU :
AF4815
product name :
Human/Mouse/Rat Vang-like Protein 2/VANGL2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse/Rat Vang-like Protein 2/VANGL2 Antibody from R&D Systems is a sheep polyclonal antibody to Vang-like Protein 2/VANGL2. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat Vang-like Protein 2/VANGL2 Antibody has been validated for the following applications: Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
Vang-like Protein 2/VANGL2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Sheep
immunogen :
E. coli -derived recombinant human Vang-like Protein 2/VANGL2, Gln241-Val521, Accession # Q9ULK5
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human, mouse, and rat Vang-like Protein 2/VANGL2 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human VANGL1 is observed.
gene symbol :
VANGL2
top caption :
Detection of Human/Mouse/Rat Vang-like Protein 2/ VANGL2 antibody by Western Blot.
accessionNumbers :
Q9ULK5
applications :
Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
469 USD
alt names :
KIAA1215Loop-tail protein 1 homolog, loop-tail-associated protein, LPP1, LTAP, LTAPVan Gogh-like protein 2, MGC119403, MGC119404, STB1, STB1Strabismus 1, STBM, STBM1, Strabismus, vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila), Vang like Protein 2, VANGL2, vang-like 2 (van gogh, Drosophila), vang-like protein 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.