Human LAMP-1/CD107a Lumenal Domain Antibody | R&D Systems AF4800 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human LAMP-1/CD107a Lumenal Domain Antibody

catalog :

AF4800

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 7

Reference
Cason S, Holzbaur E. Axonal transport of autophagosomes is regulated by dynein activators JIP3/JIP4 and ARF/RAB GTPases. bioRxiv. 2023;: pubmed publisher
Gallagher E, Holzbaur E. The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy. Cell Rep. 2023;42:112037 pubmed publisher
Cason S, Mogre S, Holzbaur E, Koslover E. Spatiotemporal analysis of axonal autophagosome-lysosome dynamics reveals limited fusion events and slow maturation. Mol Biol Cell. 2022;33:ar123 pubmed publisher
Ghosh S, Dellibovi Ragheb T, Kerviel A, Pak E, Qiu Q, Fisher M, et al. β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway. Cell. 2020;183:1520-1535.e14 pubmed publisher
Dissanayake K, Nõmm M, Lättekivi F, Ressaissi Y, Godakumara K, Lavrits A, et al. Individually cultured bovine embryos produce extracellular vesicles that have the potential to be used as non-invasive embryo quality markers. Theriogenology. 2020;149:104-116 pubmed publisher
Kolodziejek A, Altura M, Fan J, Petersen E, Cook M, Brzovic P, et al. Salmonella Translocated Effectors Recruit OSBP1 to the Phagosome to Promote Vacuolar Membrane Integrity. Cell Rep. 2019;27:2147-2156.e5 pubmed publisher
Qureshi Y, Patel V, Berman D, Kothiya M, Neufeld J, Vardarajan B, et al. An Alzheimer's Disease-Linked Loss-of-Function CLN5 Variant Impairs Cathepsin D Maturation, Consistent with a Retromer Trafficking Defect. Mol Cell Biol. 2018;38: pubmed publisher

product information

master code :

AF4800

SKU :

AF4800

product name :

Human LAMP-1/CD107a Lumenal Domain Antibody

unit size :

100 ug (also 25 ug)

description :

The Human LAMP-1/CD107a Lumenal Domain Antibody from R&D Systems is a sheep polyclonal antibody to LAMP-1/CD107a. This antibody reacts with human,mouse,primate - chlorocebus aethiops (african green monkey),rat. The Human LAMP-1/CD107a Lumenal Domain Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Microarray.

target :

LAMP-1/CD107a

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Sheep

immunogen :

Mouse myeloma cell line NS0-derived recombinant human LAMP1/CD107a, Ala28-Asn380, Accession # P11279

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Primate - Chlorocebus aethiops (African Green Monkey),Rat

specificity :

Detects human LAMP1/CD107a Lumenal Domain in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse LAMP1 is observed.

gene symbol :

LAMP1

top caption :

Detection of Human LAMP-1/CD107a antibody by Western Blot.

accessionNumbers :

P11279

applications :

Western Blot,Immunocytochemistry,Microarray

USD :

469 USD

alt names :

CD107 antigen-like family member A, CD107a, CD107a antigen, LAMP1, LAMP-1, LAMPA, LGP120, lysosomal-associated membrane protein 1, lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage