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company name :
R&D Systems
product type :
antibody
product name :
Human FoxF1 Antibody
catalog :
AF4798
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 26
Reference
Gomez Arroyo J, Houweling A, Bogaard H, Aman J, Kitzmiller J, Porollo A, et al. Role of Forkhead box F1 in the Pathobiology of Pulmonary Arterial Hypertension. bioRxiv. 2024;: pubmed publisher
Shirazi S, Negretti N, Jetter C, Sharkey A, Garg S, Kapp M, et al. Bronchopulmonary Dysplasia with Pulmonary Hypertension Associates with Loss of Semaphorin Signaling and Functional Decrease in FOXF1 Expression. bioRxiv. 2024;: pubmed publisher
Edwards N, Kashyap A, Warren A, Agricola Z, Kenny A, Shen Y, et al. Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in trachea-esophageal morphogenesis. bioRxiv. 2023;: pubmed publisher
Kolesnichenko O, Flood H, Zhang Y, Ustiyan V, Cuervo Jimenez H, Kalin T, et al. Endothelial progenitor cells derived from embryonic stem cells prevent alveolar simplification in a murine model of bronchopulmonary dysplasia. Front Cell Dev Biol. 2023;11:1209518 pubmed publisher
Bian F, Lan Y, Zhao S, Deng Z, Shukla S, Acharya A, et al. Lung endothelial cells regulate pulmonary fibrosis through FOXF1/R-Ras signaling. Nat Commun. 2023;14:2560 pubmed publisher
Susa K, Kobayashi K, Galichon P, Matsumoto T, Tamura A, Hiratsuka K, et al. ATP/ADP biosensor organoids for drug nephrotoxicity assessment. Front Cell Dev Biol. 2023;11:1138504 pubmed publisher
Liu X, Geng Y, Liang J, Coelho A, Yao C, Deng N, et al. HER2 drives lung fibrosis by activating a metastatic cancer signature in invasive lung fibroblasts. J Exp Med. 2022;219: pubmed publisher
Kishimoto K, Iwasawa K, Sorel A, Ferran Heredia C, Han L, Morimoto M, et al. Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems. Nat Protoc. 2022;17:2699-2719 pubmed publisher
Fink E, Sona S, Tran U, Desprez P, Bradley M, Qiu H, et al. Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter. Dev Cell. 2022;57:1899-1916.e6 pubmed publisher
Zhong G, Ahimaz P, Edwards N, Hagen J, Faure C, Lu Q, et al. Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas. HGG Adv. 2022;3:100107 pubmed publisher
Cheng K, Seita Y, Moriwaki T, Noshiro K, Sakata Y, Hwang Y, et al. The developmental origin and the specification of the adrenal cortex in humans and cynomolgus monkeys. Sci Adv. 2022;8:eabn8485 pubmed publisher
Sun X, Perl A, Li R, Bell S, Sajti E, Kalinichenko V, et al. A census of the lung: CellCards from LungMAP. Dev Cell. 2022;57:112-145.e2 pubmed publisher
Eicher A, Kechele D, Sundaram N, Berns H, Poling H, Haines L, et al. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Cell Stem Cell. 2022;29:36-51.e6 pubmed publisher
Sasaki K, Oguchi A, Cheng K, Murakawa Y, Okamoto I, Ohta H, et al. The embryonic ontogeny of the gonadal somatic cells in mice and monkeys. Cell Rep. 2021;35:109075 pubmed publisher
Milewski D, Shukla S, Gryder B, Pradhan A, Donovan J, Sudha P, et al. FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma. Oncogene. 2021;40:2182-2199 pubmed publisher
Wu G, Lee Y, Gulla E, Potter A, Kitzmiller J, Ruben M, et al. Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease. elife. 2021;10: pubmed publisher
Nasr T, Holderbaum A, Chaturvedi P, Agarwal K, Kinney J, Daniels K, et al. Disruption of a hedgehog-foxf1-rspo2 signaling axis leads to tracheomalacia and a loss of sox9+ tracheal chondrocytes. Dis Model Mech. 2020;14: pubmed publisher
Deepe R, Fitzgerald E, Wolters R, Drummond J, Guzman K, Hoff M, et al. The Mesenchymal Cap of the Atrial Septum and Atrial and Atrioventricular Septation. J Cardiovasc Dev Dis. 2020;7: pubmed publisher
Fabik J, Kovacova K, Kozmik Z, Machon O. Neural crest cells require Meis2 for patterning the mandibular arch via the Sonic hedgehog pathway. Biol Open. 2020;9: pubmed publisher
Belair D, Lu G, Waller L, Gustin J, Collins N, Kolaja K. Thalidomide Inhibits Human iPSC Mesendoderm Differentiation by Modulating CRBN-dependent Degradation of SALL4. Sci Rep. 2020;10:2864 pubmed publisher
Du Y, Clair G, Al Alam D, Danopoulos S, Schnell D, Kitzmiller J, et al. Integration of transcriptomic and proteomic data identifies biological functions in cell populations from human infant lung. Am J Physiol Lung Cell Mol Physiol. 2019;317:L347-L360 pubmed publisher
Xu J, Liu H, Lan Y, Adam M, Clouthier D, POTTER S, et al. Hedgehog signaling patterns the oral-aboral axis of the mandibular arch. elife. 2019;8: pubmed publisher
HERRING B, Hoggatt A, Gupta A, Wo J. Gastroparesis is associated with decreased FOXF1 and FOXF2 in humans, and loss of FOXF1 and FOXF2 results in gastroparesis in mice. Neurogastroenterol Motil. 2019;31:e13528 pubmed publisher
Black M, Milewski D, Le T, Ren X, Xu Y, Kalinichenko V, et al. FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts. Cell Rep. 2018;23:442-458 pubmed publisher
McCracken K, Aihara E, Martin B, Crawford C, Broda T, Treguier J, et al. Wnt/β-catenin promotes gastric fundus specification in mice and humans. Nature. 2017;541:182-187 pubmed publisher
Milewski D, Pradhan A, Wang X, Cai Y, Le T, Turpin B, et al. FoxF1 and FoxF2 transcription factors synergistically promote rhabdomyosarcoma carcinogenesis by repressing transcription of p21Cip1 CDK inhibitor. Oncogene. 2017;36:850-862 pubmed publisher
product information
master code :
AF4798
SKU :
AF4798
product name :
Human FoxF1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human FoxF1 Antibody from R&D Systems is a goat polyclonal antibody to FoxF1. This antibody reacts with human,mouse,transgenic mouse,frog - xenopus (african clawed frog). The Human FoxF1 Antibody has been validated for the following applications: Immunohistochemistry,IHC-,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry.
target :
FoxF1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human FoxF1, Met154-Met379, Accession # Q12946
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse,Frog - Xenopus (African Clawed Frog)
specificity :
Detects human FoxF1 in Western blots.
gene symbol :
FOXF1
top caption :
Detection of Human FoxF1 antibody by Western Blot.
accessionNumbers :
Q12946
applications :
Immunohistochemistry,IHC-,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry
USD :
499 USD
alt names :
FKHL5, FKHL5MGC105125, forkhead box F1, forkhead box protein F1, Forkhead, drosophila, homolog-like 5, Forkhead-related activator 1, Forkhead-related protein FKHL5, Forkhead-related transcription factor 1, FREAC-1, FREAC1ACDMPV
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.