product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Mouse CCL5/RANTES Antibody
catalog :
AF478
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 21
Reference
Dean I, Lee C, Tuong Z, Li Z, Tibbitt C, Willis C, et al. Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity. Nat Commun. 2024;15:683 pubmed publisher
Liu H, Zhang L, Liu Z, Lin J, He X, Wu S, et al. Galectin-3 as TREM2 upstream factor contributes to lung ischemia-reperfusion injury by regulating macrophage polarization. iScience. 2023;26:107496 pubmed publisher
Andre A, Rees K, O Connor S, Severson G, Newbern J, Wilson Rawls J, et al. Single cell analysis reveals satellite cell heterogeneity for proinflammatory chemokine expression. Front Cell Dev Biol. 2023;11:1084068 pubmed publisher
Vorontsova A, Cooper T, Haj Shomaly J, Benguigui M, Levin S, Manobla B, et al. Chemotherapy-induced tumor immunogenicity is mediated in part by megakaryocyte-erythroid progenitors. Oncogene. 2023;42:771-781 pubmed publisher
Kochumon S, Hasan A, Al Rashed F, Sindhu S, Thomas R, Jacob T, et al. Increased Adipose Tissue Expression of IL-23 Associates with Inflammatory Markers in People with High LDL Cholesterol. Cells. 2022;11: pubmed publisher
Kim H, Kim W, Shin H, Yoon H, Moon J, Lee E, et al. ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation. Cell Mol Life Sci. 2022;79:155 pubmed publisher
Tang S, Su B, Tao T, Yan W, Zhang R, Qin X, et al. RGMa regulates CCL5 expression via the BMP receptor in experimental autoimmune encephalomyelitis mice and endothelial cells. Mol Med Rep. 2022;25: pubmed publisher
Wang J, Zhang Y, Xiao Y, Yuan X, Li P, Wang X, et al. Boosting immune surveillance by low-dose PI3K inhibitor facilitates early intervention of breast cancer. Am J Cancer Res. 2021;11:2005-2024 pubmed
Seyfried A, McCabe A, Smith J, Calvi L, MacNamara K. CCR5 maintains macrophages in the bone marrow and drives hematopoietic failure in a mouse model of severe aplastic anemia. Leukemia. 2021;35:3139-3151 pubmed publisher
Galeano Niño J, Pageon S, Tay S, Colakoglu F, Kempe D, Hywood J, et al. Cytotoxic T cells swarm by homotypic chemokine signalling. elife. 2020;9: pubmed publisher
Yagura K, Ohtaki H, Tsumuraya T, Sato A, Miyamoto K, Kawada N, et al. The enhancement of CCL2 and CCL5 by human bone marrow-derived mesenchymal stem/stromal cells might contribute to inflammatory suppression and axonal extension after spinal cord injury. PLoS ONE. 2020;15:e0230080 pubmed publisher
William M, Leroux L, Chaparro V, Graber T, Alain T, Jaramillo M. Translational repression of Ccl5 and Cxcl10 by 4E-BP1 and 4E-BP2 restrains the ability of mouse macrophages to induce migration of activated T cells. Eur J Immunol. 2019;49:1200-1212 pubmed publisher
Mouton A, Ma Y, Rivera Gonzalez O, Daseke M, Flynn E, Freeman T, et al. Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis. Basic Res Cardiol. 2019;114:6 pubmed publisher
Chen L, Gu J, Qian Y, Li M, Qian Y, Xu M, et al. Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity. Cell Mol Gastroenterol Hepatol. 2019;7:623-639 pubmed publisher
Böttcher J, Bonavita E, Chakravarty P, Blees H, Cabeza Cabrerizo M, Sammicheli S, et al. NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control. Cell. 2018;172:1022-1037.e14 pubmed publisher
Wang P, Zhou S, Ge Y, Lu M, Liu Z, Gong R. Valproate hampers podocyte acquisition of immune phenotypes via intercepting the GSK3? facilitated NFkB activation. Oncotarget. 2017;8:88332-88344 pubmed publisher
Suffee N, Le Visage C, Hlawaty H, Aid Launais R, Vanneaux V, Larghero J, et al. Pro-angiogenic effect of RANTES-loaded polysaccharide-based microparticles for a mouse ischemia therapy. Sci Rep. 2017;7:13294 pubmed publisher
Wang C, Yeo S, Haas M, Guan J. Autophagy gene FIP200 in neural progenitors non-cell autonomously controls differentiation by regulating microglia. J Cell Biol. 2017;216:2581-2596 pubmed publisher
Thaney V, O Neill A, Hoefer M, Maung R, Sanchez A, Kaul M. IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury. Sci Rep. 2017;7:46514 pubmed publisher
Chu Y, Wan S, Chang Y, Lee C, Wu Hsieh B, Anderson R, et al. Antibodies against nonstructural protein 1 protect mice from dengue virus-induced mast cell activation. Lab Invest. 2017;: pubmed publisher
Chandra G, Rangasamy S, Roy A, Kordower J, Pahan K. Neutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease. J Biol Chem. 2016;291:15267-81 pubmed publisher
product information
brand :
R&D Systems
master code :
AF478
SKU :
AF478
product name :
Mouse CCL5/RANTES Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse CCL5/RANTES Antibody from R&D Systems is a goat polyclonal antibody to CCL5/RANTES. This antibody reacts with human,mouse,rat. The Mouse CCL5/RANTES Antibody has been validated for the following applications: IF/IHC,In vivo assay,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
CCL5/RANTES
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Neutralization 0.07-0.3 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant mouse CCL5/RANTES
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects mouse CCL5/RANTES in direct ELISAs and Western blots.
gene symbol :
CCL5
endotoxin note :
<0.30 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Chemotaxis Induced by CCL5/RANTES and Neutralization by Mouse CCL5/RANTES Antibody.
applications :
Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Neutralization,Immunocytochemistry
USD :
499 USD
alt names :
chemokine (C-C motif) ligand 5, D17S136Enormally T-expressed, and presumably secreted, EoCP, Eosinophil chemotactic cytokine, RANTES, SISd, SIS-delta, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), member 5, Small-inducible cytokine A5, T cell-specific protein P228, T-cell specific protein p288, TCP228T-cell-specific protein RANTES
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.