Mouse VEGFR1/Flt-1 Antibody | R&D Systems AF471 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse VEGFR1/Flt-1 Antibody

catalog :

AF471

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:200; loading ...; fig 6a	Tirronen A, Downes N, Huusko J, Laakkonen J, Tuomainen T, Tavi P, et al. The Ablation of VEGFR-1 Signaling Promotes Pressure Overload-Induced Cardiac Dysfunction and Sudden Death. Biomolecules. 2021;11: pubmed publisher
	van Aanhold C, Koudijs A, Dijkstra K, Wolterbeek R, Bruijn J, van Kooten C, et al. The VEGF Inhibitor Soluble Fms-like Tyrosine Kinase 1 Does Not Promote AKI-to-CKD Transition. Int J Mol Sci. 2022;23: pubmed publisher
	Karaman S, Paavonsalo S, Heinolainen K, Lackman M, Ranta A, Hemanthakumar K, et al. Interplay of vascular endothelial growth factor receptors in organ-specific vessel maintenance. J Exp Med. 2022;219: pubmed publisher
	Viallard C, Audiger C, Popovic N, Akla N, Lanthier K, Legault Navarrete I, et al. BMP9 signaling promotes the normalization of tumor blood vessels. Oncogene. 2020;39:2996-3014 pubmed publisher
	Verma M, Shimizu Motohashi Y, Asakura Y, Ennen J, Bosco J, Zhou Z, et al. Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy. PLoS Genet. 2019;15:e1008468 pubmed publisher
	Zhao F, Zhou L, Liu J, Xu Z, Ping W, Li H, et al. Construction of a vascularized bladder with autologous adipose-derived stromal vascular fraction cells combined with bladder acellular matrix via tissue engineering. J Tissue Eng. 2019;10:2041731419891256 pubmed publisher
	Vaquié A, Sauvain A, Duman M, Nocera G, Egger B, Meyenhofer F, et al. Injured Axons Instruct Schwann Cells to Build Constricting Actin Spheres to Accelerate Axonal Disintegration. Cell Rep. 2019;27:3152-3166.e7 pubmed publisher
	Teixeira S, Lopes D, Gimenes S, Teixeira T, Da Silva M, Brígido R, et al. Mechanistic Insights into the Anti-angiogenic Activity of Trypanosoma cruzi Protein 21 and its Potential Impact on the Onset of Chagasic Cardiomyopathy. Sci Rep. 2017;7:44978 pubmed publisher
	Ola R, Dubrac A, Han J, Zhang F, Fang J, Larrivee B, et al. PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia. Nat Commun. 2016;7:13650 pubmed publisher
	Hou S, Nilchi L, Li X, Gangaraju S, Jiang S, Aylsworth A, et al. Semaphorin3A elevates vascular permeability and contributes to cerebral ischemia-induced brain damage. Sci Rep. 2015;5:7890 pubmed publisher
	Gerhardt H, Golding M, Fruttiger M, Ruhrberg C, Lundkvist A, Abramsson A, et al. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol. 2003;161:1163-77 pubmed

product information

master code :

AF471

SKU :

AF471

product name :

Mouse VEGFR1/Flt-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse VEGFR1/Flt-1 Antibody from R&D Systems is a goat polyclonal antibody to VEGFR1/Flt-1. This antibody reacts with mouse,rat,transgenic mouse. The Mouse VEGFR1/Flt-1 Antibody has been validated for the following applications: Immunohistochemistry,Bioassay,Neutralization,ELISA Development,IHC frozen fixed,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture (Matched Antibody Pair),CyTOF-ready.

target :

VEGFR1/Flt-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse VEGFR1/Flt-1, Ser27-Glu759, Accession # P35969

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Rat,Transgenic Mouse

specificity :

Detects mouse VEGFR1/Flt-1 in ELISAs and Western blots.

gene symbol :

FLT1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by VEGF164and Neutralization by Mouse VEGFR1/Flt-1 Antibody.

accessionNumbers :

P35969

applications :

Immunohistochemistry,Bioassay,Neutralization,ELISA Development,IHC frozen fixed,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture (Matched Antibody Pair),CyTOF-ready

USD :

509 USD

alt names :

EC 2.7.10, EC 2.7.10.1, FLT, FLT1, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage