Mouse CXCL13/BLC/BCA-1 Antibody | R&D Systems AF470 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse CXCL13/BLC/BCA-1 Antibody

catalog :

AF470

quantity :

100 ug (also 25 ug)

price :

519 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 33

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:100; fig s8b	Ozmadenci D, Shankara Narayanan J, Andrew J, Ojalill M, Barrie A, Jiang S, et al. Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis. Proc Natl Acad Sci U S A. 2022;119:e2117065119 pubmed publisher
	Norman K, Lang G, Shadid T, Honold S, Reel J, Cox M, et al. Clostridioides difficile toxin B subverts germinal center and antibody recall responses by stimulating a drug-treatable CXCR4-dependent mechanism. Cell Rep. 2024;43:114245 pubmed publisher
	Fitzpatrick Z, Ghabdan Zanluqui N, Rosenblum J, Tuong Z, Lee C, Chandrashekhar V, et al. Venous-plexus-associated lymphoid hubs support meningeal humoral immunity. Nature. 2024;628:612-619 pubmed publisher
	Marcial Ju xe1 rez E, P xe9 rez Toledo M, Nayar S, Pipi E, Alshayea A, Persaud R, et al. Salmonella infection induces the reorganization of follicular dendritic cell networks concomitant with the failure to generate germinal centers. iScience. 2023;26:106310 pubmed publisher
	Rayasam A, Kijak J, Kissel L, Choi Y, Kim T, Hsu M, et al. CXCL13 expressed on inflamed cerebral blood vessels recruit IL-21 producing TFH cells to damage neurons following stroke. J Neuroinflammation. 2022;19:125 pubmed publisher
	Mahmoud W, Perniss A, Poharkar K, Soultanova A, Pfeil U, Hoek A, et al. CXCL13 is expressed in a subpopulation of neuroendocrine cells in the murine trachea and lung. Cell Tissue Res. 2022;390:35-49 pubmed publisher
	Ma Q, Chen Y, Qin Q, Guo F, Wang Y, Li D. CXCL13 expression in mouse 4T1 breast cancer microenvironment elicits antitumor immune response by regulating immune cell infiltration. Precis Clin Med. 2021;4:155-167 pubmed publisher
	Iwanaga N, Chen K, Yang H, Lu S, Hoffmann J, Wanek A, et al. Vaccine-driven lung TRM cells provide immunity against Klebsiella via fibroblast IL-17R signaling. Sci Immunol. 2021;6:eabf1198 pubmed publisher
	Ciurkiewicz M, Floess S, Beckstette M, Kummerfeld M, Baumg xe4 rtner W, Huehn J, et al. Transcriptome analysis following neurotropic virus infection reveals faulty innate immunity and delayed antigen presentation in mice susceptible to virus-induced demyelination. Brain Pathol. 2021;31:e13000 pubmed publisher
	Mansouri S, Katikaneni D, Gogoi H, Jin L. Monocyte-Derived Dendritic Cells (moDCs) Differentiate into Bcl6+ Mature moDCs to Promote Cyclic di-GMP Vaccine Adjuvant-Induced Memory TH Cells in the Lung. J Immunol. 2021;206:2233-2245 pubmed publisher
	Trolese M, Mariani A, Terao M, De Paola M, Fabbrizio P, Sironi F, et al. CXCL13/CXCR5 signalling is pivotal to preserve motor neurons in amyotrophic lateral sclerosis. EBioMedicine. 2020;62:103097 pubmed publisher
	Zhang Q, Li J, Jiang K, Wang R, Ge J, Yang H, et al. CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner. Theranostics. 2020;10:10619-10633 pubmed publisher
	Li L, Hole C, Rangel Moreno J, Khader S, Doering T. Cryptococcus neoformans Evades Pulmonary Immunity by Modulating Xylose Precursor Transport. Infect Immun. 2020;88: pubmed publisher
	Streich K, Smoczek M, Hegermann J, Dittrich Breiholz O, Bornemann M, Siebert A, et al. Dietary lipids accumulate in macrophages and stromal cells and change the microarchitecture of mesenteric lymph nodes. J Adv Res. 2020;24:291-300 pubmed publisher
	Muthalagu N, Monteverde T, Raffo Iraolagoitia X, Wiesheu R, Whyte D, Hedley A, et al. Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2020;10:872-887 pubmed publisher
	Jia X, Gábris F, Jacobsen O, Bedics G, Botz B, Helyes Z, et al. Foliate Lymphoid Aggregates as Novel Forms of Serous Lymphocyte Entry Sites of Peritoneal B Cells and High-Grade B Cell Lymphomas. J Immunol. 2020;204:23-36 pubmed publisher
	Xu L, Li Y, Yang C, Loughran P, Liao H, Hoffman R, et al. TLR9 signaling in fibroblastic reticular cells regulates peritoneal immunity. J Clin Invest. 2019;129:3657-3669 pubmed publisher
	Denton A, Carr E, Magiera L, Watts A, Fearon D. Embryonic FAP+ lymphoid tissue organizer cells generate the reticular network of adult lymph nodes. J Exp Med. 2019;216:2242-2252 pubmed publisher
	Dubey L, Ludewig B, Luther S, Harris N. IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells. Cell Rep. 2019;27:2442-2458.e5 pubmed publisher
	Atif S, Mack D, McKee A, Rangel Moreno J, Martin A, Getahun A, et al. Protective role of B cells in sterile particulate-induced lung injury. JCI Insight. 2019;5: pubmed publisher
	Billi A, Gharaee Kermani M, Fullmer J, Tsoi L, Hill B, Gruszka D, et al. The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity. JCI Insight. 2019;4: pubmed publisher
	Cheng H, Onder L, Novković M, Soneson C, Lütge M, Pikor N, et al. Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp. Nat Commun. 2019;10:1739 pubmed publisher
	Gallotta M, Assi H, Degagné E, Kannan S, Coffman R, Guiducci C. Inhaled TLR9 Agonist Renders Lung Tumors Permissive to PD-1 Blockade by Promoting Optimal CD4+ and CD8+ T-cell Interplay. Cancer Res. 2018;78:4943-4956 pubmed publisher
	Sundar I, Rashid K, Gerloff J, Rangel Moreno J, Li D, Rahman I. Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema. FASEB J. 2018;32:4955-4971 pubmed publisher
	Porras G, Ayuso M, González Manchón C. Leukocyte-endothelial cell interaction is enhanced in podocalyxin-deficient mice. Int J Biochem Cell Biol. 2018;99:72-79 pubmed publisher
	Respatika D, Saito Y, Washio K, Komori S, Kotani T, Okazawa H, et al. Role of SIRPα in Homeostatic Regulation of T Cells and Fibroblastic Reticular Cells in the Spleen. Kobe J Med Sci. 2017;63:E22-E29 pubmed
	Mzinza D, Fleige H, Laarmann K, Willenzon S, Ristenpart J, Spanier J, et al. Application of light sheet microscopy for qualitative and quantitative analysis of bronchus-associated lymphoid tissue in mice. Cell Mol Immunol. 2018;15:875-887 pubmed publisher
	Hill D, Yu L, Gao H, Balic J, West A, Oshima H, et al. Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development. Int J Cancer. 2018;143:167-178 pubmed publisher
	Alturaiki W, McFarlane A, Rose K, Corkhill R, McNamara P, Schwarze J, et al. Expression of the B cell differentiation factor BAFF and chemokine CXCL13 in a murine model of Respiratory Syncytial Virus infection. Cytokine. 2018;110:267-271 pubmed publisher
	Turner V, Mabbott N. Ageing adversely affects the migration and function of marginal zone B cells. Immunology. 2017;151:349-362 pubmed publisher
	Eddens T, Elsegeiny W, Garcia Hernadez M, Castillo P, Trevejo Nuñez G, Serody K, et al. Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity. Cell Rep. 2017;18:3078-3090 pubmed publisher
	Okuneva O, Li Z, Körber I, Tegelberg S, Joensuu T, Tian L, et al. Brain inflammation is accompanied by peripheral inflammation in Cstb -/- mice, a model for progressive myoclonus epilepsy. J Neuroinflammation. 2016;13:298 pubmed
	Lee K, Spata M, Bayne L, Buza E, Durham A, Allman D, et al. Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia. Cancer Discov. 2016;6:256-69 pubmed publisher

product information

brand :

R&D Systems

master code :

AF470

SKU :

AF470

product name :

Mouse CXCL13/BLC/BCA-1 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Mouse CXCL13/BLC/BCA-1 Antibody from R&D Systems is a goat polyclonal antibody to CXCL13/BLC/BCA-1. This antibody reacts with human,mouse. The Mouse CXCL13/BLC/BCA-1 Antibody has been validated for the following applications: Neutralization,Immunohistochemistry,Bioassay,IHC-F,Migration Assay,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry.

target :

CXCL13/BLC/BCA-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 20-50 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant mouse CXCL13/BLC/BCA-1, Ile22-Ala109, Accession # Q3U1E8

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects mouse CXCL13/BLC/BCA-1 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) CXCL13 and rhGCP-2 is observed.

gene symbol :

CXCL13

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Chemotaxis Induced by CXCL13/BLC/BCA-1 and Neutralization by Mouse CXCL13/BLC/BCA-1 Antibody.

accessionNumbers :

Q3U1E8

applications :

Bioassay,IHC-F,Migration Assay,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Neutralization,Immunocytochemistry

USD :

519 USD

alt names :

ANGIE, ANGIE2, B cell-attracting chemokine 1, B lymphocyte chemoattractant, BCA1, BCA-1, BCA1B-cell chemoattractant, BCA-1CXC chemokine BLC, B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1), BLC, BLCSmall-inducible cytokine B13, BLR1L, B-lymphocyte chemoattractant, chemokine (C-X-C motif) ligand 13, chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant), C-X-C motif chemokine 13, SCYB13, SCYB13B-cell-attracting chemokine 1, small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cellchemoattractant)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage