Mouse LIF Antibody | R&D Systems AF449 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse LIF Antibody

catalog :

AF449

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunocytochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 5

Reference
Cai W, Shi L, Zhao J, Xu F, Dufort C, Ye Q, et al. Neuroprotection against ischemic stroke requires a specific class of early responder T cells in mice. J Clin Invest. 2022;132: pubmed publisher
L xf6 rchner H, Adrian Segarra J, Waechter C, Wagner R, G xf3 es M, Brachmann N, et al. Concomitant Activation of OSM and LIF Receptor by a Dual-Specific hlOSM Variant Confers Cardioprotection after Myocardial Infarction in Mice. Int J Mol Sci. 2021;23: pubmed publisher
Biffi G, Oni T, Spielman B, Hao Y, Elyada E, Park Y, et al. IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2019;9:282-301 pubmed publisher
Tang Y, Xiong S, Yu P, Liu F, Cheng L. Direct Conversion of Mouse Fibroblasts into Neural Stem Cells by Chemical Cocktail Requires Stepwise Activation of Growth Factors and Nup210. Cell Rep. 2018;24:1355-1362.e3 pubmed publisher
Won H, Moreira D, Gao C, Duttagupta P, Zhao X, Manuel E, et al. TLR9 expression and secretion of LIF by prostate cancer cells stimulates accumulation and activity of polymorphonuclear MDSCs. J Leukoc Biol. 2017;102:423-436 pubmed publisher

product information

master code :

AF449

SKU :

AF449

product name :

Mouse LIF Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse LIF Antibody from R&D Systems is a goat polyclonal antibody to LIF. This antibody reacts with mouse,transgenic mouse. The Mouse LIF Antibody has been validated for the following applications: Neutralization,Bioassay,ELISA Development,Western Blot,Immunocytochemistry.

target :

LIF

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse LIF

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Transgenic Mouse

specificity :

Detects mouse LIF in direct ELISAs and Western blots. In direct ELISAs and Western blots (non-reducing conditions), less than 5% cross-reactivity with recombinant human (rh) LIF is observed. In direct ELISAs, no cross-reactivity with rhCNTF, recombinant mouse (rm) G-CSF, rmIL-6, and rmOSM is observed.

gene symbol :

LIF

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

IL-6 Secretion Induced by LIF and Neutralization by Mouse LIF Antibody.

applications :

Neutralization,Bioassay,ELISA Development,Western Blot,Immunocytochemistry

USD :

489 USD

alt names :

CDF, D factor, DIA, differentiation inhibitory activity, differentiation stimulating factor, Differentiation-stimulating factor, Emfilermin, HILDA, HILDAcholinergic differentiation factor, leukemia inhibitory factor, leukemia inhibitory factor (cholinergic differentiation factor), Melanoma-derived LPL inhibitor, MLPLI

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage