product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat Contactin-2/TAG1 Antibody
catalog :
AF4439
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section, immunohistochemistry knockout validation
more info or order :
R&D Systems product webpage
citations: 28
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:50; loading ...; fig s1c
Delgado C, Bu L, Zhang J, Liu F, Sall J, Liang F, et al. Neural cell adhesion molecule is required for ventricular conduction system development. Development. 2021;148: pubmed publisher
Oh Y, Abid R, Dababneh S, Bakr M, Aslani T, Cook D, et al. Transcriptional regulation of the postnatal cardiac conduction system heterogeneity. Nat Commun. 2024;15:6550 pubmed publisher
Sauvé F, Nampoothiri S, Clarke S, Fernandois D, Ferreira Co xea lho C, Dewisme J, et al. Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death. EBioMedicine. 2023;96:104784 pubmed publisher
Tabata H, Mori D, Matsuki T, Yoshizaki K, Asai M, Nakayama A, et al. Histological Analysis of a Mouse Model of the 22q11.2 Microdeletion Syndrome. Biomolecules. 2023;13: pubmed publisher
Dailey Krempel B, Martin A, Jo H, Junge H, Chen Z. A tug of war between DCC and ROBO1 signaling during commissural axon guidance. Cell Rep. 2023;42:112455 pubmed publisher
Maejima I, Hara T, Tsukamoto S, Koizumi H, Kawauchi T, Akuzawa T, et al. RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution. Commun Biol. 2023;6:440 pubmed publisher
Cifuentes Diaz C, Canali G, Garcia M, Druart M, Manett T, Savariradjane M, et al. Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse. Front Neurosci. 2023;17:1100121 pubmed publisher
Cotellessa L, Marelli F, Duminuco P, Adamo M, Papadakis G, Bartoloni L, et al. Defective jagged-1 signaling affects GnRH development and contributes to congenital hypogonadotropic hypogonadism. JCI Insight. 2023;8: pubmed publisher
Goodyer W, Beyersdorf B, Duan L, van den Berg N, Mantri S, Galdos F, et al. In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022;132: pubmed publisher
Wang Y, Ma L, Jia S, Liu D, Gu H, Wei X, et al. Serum exosomal coronin 1A and dynamin 2 as neural tube defect biomarkers. J Mol Med (Berl). 2022;100:1307-1319 pubmed publisher
Jacobi A, Tran N, Yan W, Benhar I, Tian F, Schaffer R, et al. Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells. Neuron. 2022;: pubmed publisher
Barefield D, Yamakawa S, Tahtah I, Sell J, Broman M, Laforest B, et al. Partial and complete loss of myosin binding protein H-like cause cardiac conduction defects. J Mol Cell Cardiol. 2022;169:28-40 pubmed publisher
Company V, Moreno Cerdá A, Andreu Cervera A, Murcia Ramón R, Almagro García F, Echevarria D, et al. Wnt1 Role in the Development of the Habenula and the Fasciculus Retroflexus. Front Cell Dev Biol. 2021;9:755729 pubmed publisher
Jorgensen R, Katta M, Wolfe J, Leach D, Lavelle B, Chun J, et al. Deletion of Sphingosine 1-Phosphate receptor 1 in cardiomyocytes during development leads to abnormal ventricular conduction and fibrosis. Physiol Rep. 2021;9:e15060 pubmed publisher
Van Battum E, Heitz Marchaland C, Zagar Y, Fouquet S, Kuner R, Chedotal A. Plexin-B2 controls the timing of differentiation and the motility of cerebellar granule neurons. elife. 2021;10: pubmed publisher
Ribeiro da Silva A, Neri E, Turaça L, Dariolli R, Fonseca Alaniz M, Santos Miranda A, et al. NOTCH1 is critical for fibroblast-mediated induction of cardiomyocyte specialization into ventricular conduction system-like cells in vitro. Sci Rep. 2020;10:16163 pubmed publisher
Kaur N, Han W, Li Z, Madrigal M, Shim S, Pochareddy S, et al. Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold. Neuron. 2020;107:1197-1211.e9 pubmed publisher
Patmore D, Jassim A, Nathan E, Gilbertson R, Tahan D, Hoffmann N, et al. DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. Dev Cell. 2020;54:455-470.e5 pubmed publisher
Skarlatou S, Hérent C, Toscano E, Mendes C, Bouvier J, Zampieri N. Afadin Signaling at the Spinal Neuroepithelium Regulates Central Canal Formation and Gait Selection. Cell Rep. 2020;31:107741 pubmed publisher
Choi B, Cave C, Na C, Sockanathan S. GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation. Cell Rep. 2020;31:107540 pubmed publisher
Dierich M, Hartmann S, Dietrich N, Moeser P, Brede F, Johnson Chacko L, et al. β-Secretase BACE1 Is Required for Normal Cochlear Function. J Neurosci. 2019;39:9013-9027 pubmed publisher
Vincentz J, Firulli B, Toolan K, Arking D, Sotoodehnia N, Wan J, et al. Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function. Circ Res. 2019;125:575-589 pubmed publisher
Tai Y, Gallo N, Wang M, Yu J, Van Aelst L. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. 2019;102:358-372.e9 pubmed publisher
Flores D, Duong T, Brandenberger L, Mitra A, Shirali A, Johnson J, et al. Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype. Hum Mol Genet. 2018;27:1533-1544 pubmed publisher
Hamada N, Iwamoto I, Tabata H, Nagata K. MUNC18-1 gene abnormalities are involved in neurodevelopmental disorders through defective cortical architecture during brain development. Acta Neuropathol Commun. 2017;5:92 pubmed publisher
Onishi K, Uyeda A, Shida M, Hirayama T, Yagi T, Yamamoto N, et al. Genome Stability by DNA Polymerase β in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development. J Neurosci. 2017;37:8444-8458 pubmed publisher
Bhattacharyya S, Bhakta M, MUNSHI N. Phenotypically silent Cre recombination within the postnatal ventricular conduction system. PLoS ONE. 2017;12:e0174517 pubmed publisher
Saito Y, Miranda Rottmann S, Ruggiu M, Park C, Fak J, Zhong R, et al. NOVA2-mediated RNA regulation is required for axonal pathfinding during development. elife. 2016;5: pubmed publisher
product information
master code :
AF4439
SKU :
AF4439
product name :
Human/Mouse/Rat Contactin-2/TAG1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse/Rat Contactin-2/TAG1 Antibody from R&D Systems is a goat polyclonal antibody to Contactin-2/TAG1. This antibody reacts with human,mouse,primate,rat,transgenic mouse. The Human/Mouse/Rat Contactin-2/TAG1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.
target :
Contactin-2/TAG1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Contactin-2/TAG1, Gln31-Ser1014, Accession # Q61330
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Primate,Rat,Transgenic Mouse
specificity :
Detects mouse and rat Contactin-2 in direct ELISAs. Detects human, mouse, and rat Contactin-2 in Western blots.
gene symbol :
CNTN2
top caption :
Detection of Human, Mouse, and Rat Contactin-2/TAG1 antibody by Western Blot.
accessionNumbers :
Q61330
applications :
Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western
USD :
499 USD
alt names :
Axonal glycoprotein TAG-1, Axonin-1, axonin-1 cell adhesion molecule, AXT, CNTN2, contactin 2 (axonal), contactin 2 (transiently expressed), contactin-2, Contactin2, DKFZp781D102, FLJ37193, MGC157722, TAG1, TAG-1, TAX, TAX1, TAX-1, TAX1FLJ42746, Transient axonal glycoprotein 1, transiently-expressed axonal glycoprotein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.