product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse LAMP-1/CD107a Lumenal Domain Antibody
catalog :
AF4320
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Reference
Salas Lucia F, Escamilla S, Bianco A, Dumitrescu A, Refetoff S. Impaired T3 uptake and action in MCT8-deficient cerebral organoids underlie Allan-Herndon-Dudley syndrome. JCI Insight. 2024;9: pubmed publisher
Li J, Huang Q, Lv M, Ma W, Sun J, Zhong X, et al. Role of liensinine in sensitivity of activated macrophages to ferroptosis and in acute liver injury. Cell Death Discov. 2023;9:189 pubmed publisher
Salas Lucia F, Fekete C, Sink xf3 R, Egri P, Rada K, Ruska Y, et al. Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain. elife. 2023;12: pubmed publisher
Watson J, Ferguson H, Brady R, Ferguson J, Fullwood P, Mo H, et al. Spatially resolved phosphoproteomics reveals fibroblast growth factor receptor recycling-driven regulation of autophagy and survival. Nat Commun. 2022;13:6589 pubmed publisher
Degeer J, Datwyler A, Rickenbach C, Ommer A, Gerber D, Fimiani C, et al. Ral GTPases are critical regulators of spinal cord myelination and homeostasis. Cell Rep. 2022;40:111413 pubmed publisher
Wan T, Zhu W, Zhao Y, Zhang X, Ye R, Zuo M, et al. Astrocytic phagocytosis contributes to demyelination after focal cortical ischemia in mice. Nat Commun. 2022;13:1134 pubmed publisher
Annangi B, Lu Z, Bruniaux J, Ridoux A, da Silva V, Vantelon D, et al. Macrophage autophagy protects mice from cerium oxide nanoparticle-induced lung fibrosis. Part Fibre Toxicol. 2021;18:6 pubmed publisher
Feng W, Zhang Y, Wang Z, Xu H, Wu T, Marshall C, et al. Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer's disease mouse model with suppression of glymphatic clearance. Alzheimers Res Ther. 2020;12:125 pubmed publisher
Pal Ghosh S, Tadvalkar G, Karpinski B, Stepp M. Diurnal Control of Sensory Axon Growth and Shedding in the Mouse Cornea. Invest Ophthalmol Vis Sci. 2020;61:1 pubmed publisher
Kuang L, Hashimoto K, Huang E, Gentry M, Zhu H. Frontotemporal dementia non-sense mutation of progranulin rescued by aminoglycosides. Hum Mol Genet. 2020;29:624-634 pubmed publisher
Majer O, Liu B, Woo B, Kreuk L, Van Dis E, Barton G. Release from UNC93B1 reinforces the compartmentalized activation of select TLRs. Nature. 2019;575:371-374 pubmed publisher
Majer O, Liu B, Kreuk L, Krogan N, Barton G. UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity. Nature. 2019;575:366-370 pubmed publisher
Koike M, Shibata M, Sunabori T, Yamaguchi J, Sakimura K, Komatsu M, et al. Purkinje Cells Are More Vulnerable to the Specific Depletion of Cathepsin D Than to That of Atg7. Am J Pathol. 2017;187:1586-1600 pubmed publisher
Zhang J, Johnson J, He J, Napolitano G, Ramadass M, Rocca C, et al. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. J Biol Chem. 2017;292:10328-10346 pubmed publisher
product information
master code :
AF4320
SKU :
AF4320
product name :
Mouse LAMP-1/CD107a Lumenal Domain Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse LAMP-1/CD107a Lumenal Domain Antibody from R&D Systems is a goat polyclonal antibody to LAMP-1/CD107a. This antibody reacts with human,mouse,transgenic mouse. The Mouse LAMP-1/CD107a Lumenal Domain Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Immunohistochemistry,Immunohistochemistry-Paraffin,Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
LAMP-1/CD107a
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse LAMP1/CD107a, Leu25-Asn370, Accession # P11438
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects mouse LAMP1/CD107a Lumenal Domain in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human LAMP1 is observed.
gene symbol :
LAMP1
top caption :
Detection of Mouse LAMP-1/CD107a antibody by Western Blot.
accessionNumbers :
P11438
applications :
Immunocytochemistry,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Intracellular Staining by Flow Cytometry,CyTOF-ready
USD :
509 USD
alt names :
CD107 antigen-like family member A, CD107a, CD107a antigen, LAMP1, LAMP-1, LAMPA, LGP120, lysosomal-associated membrane protein 1, lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.