product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Plexin D1 Antibody
catalog :
AF4160
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry knockout validation
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig s2c
Maruyama K, Naemura K, Arima Y, Uchijima Y, Nagao H, Yoshihara K, et al. Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery. iScience. 2021;24:102305 pubmed publisher
Lettieri A, Oleari R, van den Munkhof M, van Battum E, Verhagen M, Tacconi C, et al. SEMA6A drives GnRH neuron-dependent puberty onset by tuning median eminence vascular permeability. Nat Commun. 2023;14:8097 pubmed publisher
Paganoni A, Cannarella R, Oleari R, Amoruso F, Antal R, Ruzza M, et al. Insulin-like Growth Factor 1, Growth Hormone, and Anti-Müllerian Hormone Receptors Are Differentially Expressed during GnRH Neuron Development. Int J Mol Sci. 2023;24: pubmed publisher
Oleari R, Lettieri A, Manzini S, Paganoni A, Andr xe9 V, Grazioli P, et al. Autism-linked NLGN3 is a key regulator of gonadotropin-releasing hormone deficiency. Dis Model Mech. 2023;16: pubmed publisher
Martins L, Brambilla I, Motta A, de Pretis S, Bhat G, Badaloni A, et al. Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity. Neuron. 2022;110:4090-4107.e11 pubmed publisher
Paganoni A, Amoruso F, Porta Pelayo J, Calleja Pérez B, Vezzoli V, Duminuco P, et al. A Novel Loss-of-Function SEMA3E Mutation in a Patient with Severe Intellectual Disability and Cognitive Regression. Int J Mol Sci. 2022;23: pubmed publisher
Szczurkowska J, Guo A, Martin J, Lee S, Martinez E, Chien C, et al. Semaphorin3A/PlexinA3 association with the Scribble scaffold for cGMP increase is required for apical dendrite development. Cell Rep. 2022;38:110483 pubmed publisher
Boulan B, Ravanello C, Peyrel A, Bosc C, Delphin C, Appaix F, et al. CRMP4-mediated fornix development involves Semaphorin-3E signaling pathway. elife. 2021;10: pubmed publisher
Burk K, Mire E, Bellon A, Hocine M, Guillot J, Moraes F, et al. Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits. Nat Commun. 2017;8:14508 pubmed publisher
Movassagh H, Saati A, Nandagopal S, Mohammed A, Tatari N, Shan L, et al. Chemorepellent Semaphorin 3E Negatively Regulates Neutrophil Migration In Vitro and In Vivo. J Immunol. 2017;198:1023-1033 pubmed publisher
Liu X, Uemura A, Fukushima Y, Yoshida Y, Hirashima M. Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1. Cell Rep. 2016;17:2299-2311 pubmed publisher
product information
master code :
AF4160
SKU :
AF4160
product name :
Human Plexin D1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Plexin D1 Antibody from R&D Systems is a goat polyclonal antibody to Plexin D1. This antibody reacts with human,monkey,mouse,primate - chlorocebus aethiops (african green monkey),rat,transgenic mouse. The Human Plexin D1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Neutralization,Immunocytochemistry,Flow Cytometry,Immunohistochemistry-Paraffin,CyTOF-ready.
target :
Plexin D1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Plexin D1, Leu47-Ala1271, Accession # Q9Y4D7
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Monkey,Mouse,Primate - Chlorocebus aethiops (African Green Monkey),Rat,Transgenic Mouse
specificity :
Detects human Plexin D1 in direct ELISAs and Western blots.
gene symbol :
PLXND1
top caption :
Detection of Human Plexin D1 antibody by Western Blot.
accessionNumbers :
Q9Y4D7
applications :
Immunohistochemistry,Western Blot,Neutralization,Immunocytochemistry,Flow Cytometry,Immunohistochemistry-Paraffin,CyTOF-ready
USD :
519 USD
alt names :
KIAA0620MGC75353, PLEXD1, plexin D1, plexin-D1, PLXND1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.