product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse M-CSF Antibody
catalog :
AF416
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization
more info or order :
citations: 10
Reference
Xu H, Lotfy P, Gelb S, Pragana A, Hehnly C, Shipley F, et al. A collaboration between immune cells and the choroid plexus epithelium in brain inflammation. bioRxiv. 2023;: pubmed publisher
Tassou A, Thouaye M, Gilabert D, Jouvenel A, Leyris J, Sonrier C, et al. Activation of neuronal FLT3 promotes exaggerated sensorial and emotional pain-related behaviors facilitating the transition from acute to chronic pain. Prog Neurobiol. 2023;222:102405 pubmed publisher
Cheng J, Ma X, Li C, Ullah R, Wang X, Long J, et al. Diet-induced inflammation in the anterior paraventricular thalamus induces compulsive sucrose-seeking. Nat Neurosci. 2022;25:1009-1013 pubmed publisher
De I, Maklakova V, Litscher S, Boyd M, Klemm L, Wang Z, et al. Microglial responses to CSF1 overexpression do not promote the expansion of other glial lineages. J Neuroinflammation. 2021;18:162 pubmed publisher
Bellomo A, Mondor I, Spinelli L, Lagueyrie M, Stewart B, Brouilly N, et al. Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages. Immunity. 2020;53:127-142.e7 pubmed publisher
Bonnardel J, T Jonck W, Gaublomme D, Browaeys R, Scott C, Martens L, et al. Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche. Immunity. 2019;51:638-654.e9 pubmed publisher
Zhou L, Peng J, Xu Y, Zeng W, Zhang J, Wei X, et al. Microglia Are Indispensable for Synaptic Plasticity in the Spinal Dorsal Horn and Chronic Pain. Cell Rep. 2019;27:3844-3859.e6 pubmed publisher
Mondor I, Baratin M, Lagueyrie M, Saro L, Henri S, Gentek R, et al. Lymphatic Endothelial Cells Are Essential Components of the Subcapsular Sinus Macrophage Niche. Immunity. 2019;50:1453-1466.e4 pubmed publisher
Rotterman T, Akhter E, Lane A, Macpherson K, Garcia V, TANSEY M, et al. Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism. J Neurosci. 2019;39:3412-3433 pubmed publisher
Mousseau M, Burma N, Lee K, Leduc Pessah H, Kwok C, Reid A, et al. Microglial pannexin-1 channel activation is a spinal determinant of joint pain. Sci Adv. 2018;4:eaas9846 pubmed publisher
product information
brand :
R&D Systems
master code :
AF416
SKU :
AF416
product name :
Mouse M-CSF Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse M-CSF Antibody from R&D Systems is a goat polyclonal antibody to M-CSF. This antibody reacts with mouse,rat. The Mouse M-CSF Antibody has been validated for the following applications: Westen Blot,Western Blot,Neutralization,Immunohistochemistry,In vivo assay,Immunocytochemistry.
target :
M-CSF
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Neutralization 0.015-0.035 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant mouse M-CSF, Lys33-Glu262, Accession # Q3U4F9
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Rat
specificity :
Detects mouse M-CSF in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human M-CSF is observed.
gene symbol :
CSF1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by M-CSF and Neutralization by Mouse M-CSF Antibody.
accessionNumbers :
Q3U4F9
applications :
Westen Blot,Immunohistochemistry,Western Blot,In vivo assay,Neutralization,Immunocytochemistry
USD :
519 USD
alt names :
colony stimulating factor 1 (macrophage), CSF1, CSF-1, Lanimostim, macrophage colony stimulating factor, macrophage colony-stimulating factor 1, MCSF, M-CSF, MCSFlanimostim, MGC31930
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.