product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse/Rat Integrin alpha 8 Antibody
catalog :
AF4076
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...
Tsutsui K, Machida H, Nakagawa A, Ahn K, Morita R, Sekiguchi K, et al. Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions. Nat Commun. 2021;12:2577 pubmed publisher
Liu J, Prahl L, Huang A, Hughes A. Measurement of adhesion and traction of cells at high yield (MATCHY) reveals an energetic ratchet driving nephron condensation. bioRxiv. 2024;: pubmed publisher
Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, et al. Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids. bioRxiv. 2023;: pubmed publisher
Martino P, Sunkara R, Heitman N, Rangl M, Brown A, Saxena N, et al. Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression. Nat Cell Biol. 2023;25:222-234 pubmed publisher
Clugston A, BODNAR A, Cerqueira D, Phua Y, Lawler A, Boggs K, et al. Chromatin accessibility and microRNA expression in nephron progenitor cells during kidney development. Genomics. 2022;114:278-291 pubmed publisher
Sung S. Co-immunostaining of ICAM-1, ICAM-2, and CD31 in Mouse Kidney Glomeruli. Bio Protoc. 2020;10:e3663 pubmed publisher
Phan Q, Fine G, Salz L, Herrera G, Wildman B, Driskell I, et al. Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate wounds. elife. 2020;9: pubmed publisher
Abbasi S, Sinha S, Labit E, Rosin N, Yoon G, Rahmani W, et al. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing. Cell Stem Cell. 2020;27:396-412.e6 pubmed publisher
Faraj R, Irizarry Alfonzo A, Puri P. Molecular characterization of nephron progenitors and their early epithelial derivative structures in the nephrogenic zone of the canine fetal kidney. Eur J Histochem. 2019;63: pubmed publisher
Oba S, Ayuzawa N, Nishimoto M, Kawarazaki W, Ueda K, Hirohama D, et al. Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells. Sci Rep. 2018;8:16338 pubmed publisher
Hung C, Wilson C, Chow Y, Schnapp L. Role of integrin alpha8 in murine model of lung fibrosis. PLoS ONE. 2018;13:e0197937 pubmed publisher
Naiman N, Fujioka K, Fujino M, Valerius M, Potter S, McMahon A, et al. Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017;41:349-365.e3 pubmed publisher
Gerl K, Steppan D, Fuchs M, Wagner C, Willam C, Kurtz A, et al. Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development. Am J Pathol. 2017;187:1496-1511 pubmed publisher
Sung S, Ge Y, Dai C, Wang H, Fu S, Sharma R, et al. Dependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 Mice. J Immunol. 2017;198:2589-2601 pubmed publisher
Clark S, Nabity M, Cianciolo R, Dufek B, Cosgrove D. X-Linked Alport Dogs Demonstrate Mesangial Filopodial Invasion of the Capillary Tuft as an Early Event in Glomerular Damage. PLoS ONE. 2016;11:e0168343 pubmed publisher
product information
brand :
R&D Systems
master code :
AF4076
SKU :
AF4076
product name :
Mouse/Rat Integrin alpha 8 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse/Rat Integrin alpha 8 Antibody from R&D Systems is a goat polyclonal antibody to Integrin alpha 8. This antibody reacts with canine,mouse,rat,transgenic mouse. The Mouse/Rat Integrin alpha 8 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.
target :
Integrin alpha 8
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.25 ug/mL, Simple Western 10 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Goat
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin alpha 8, Phe38-Phe1007, Accession # A28ARA8
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Canine,Mouse,Rat,Transgenic Mouse
specificity :
Detects mouse and rat Integrin alpha 8 in Western blots. In direct ELISAs and Western blots, approximately 30% cross-reactivity with recombinant human (rh) Integrin alpha 8 is observed, and less than 1% cross-reactivity with rhIntegrin alpha 5, recombinant mouse (rm) Integrin alpha 5, rhIntegrin alpha V and rmIntegrin alpha V is observed.
gene symbol :
ITGA8
top caption :
Detection of Mouse Integrin a8 antibody by Western Blot.
accessionNumbers :
A28ARA8
applications :
Simple Western,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
489 USD
alt names :
integrin alpha-8, integrin, alpha 8, ITGA8
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.