product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Cyr61/CCN1 Antibody
catalog :
AF4055
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, ELISA, immunohistochemistry, neutralization, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
citations: 8
Reference
Menger M, Bauer D, Bleimehl M, Scheuer C, Braun B, Herath S, et al. Sildenafil, a phosphodiesterase-5 inhibitor, stimulates angiogenesis and bone regeneration in an atrophic non-union model in mice. J Transl Med. 2023;21:607 pubmed publisher
Cheng N, Kim K, Lau L. Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2. JCI Insight. 2022;7: pubmed publisher
Ma S, Kanai R, Pobbati A, Li S, Che K, Seavey C, et al. The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras-MAPK Signaling in Epithelioid Hemangioendothelioma. Clin Cancer Res. 2022;28:3116-3126 pubmed publisher
Ren J, Wang X, Parry S, Yee C, Gorrell M, McLennan S, et al. Targeting CCN2 protects against progressive non-alcoholic steatohepatitis in a preclinical model induced by high-fat feeding and type 2 diabetes. J Cell Commun Signal. 2022;16:447-460 pubmed publisher
Wong N, Mohan J, Kopecky B, Guo S, Du L, Leid J, et al. Resident cardiac macrophages mediate adaptive myocardial remodeling. Immunity. 2021;54:2072-2088.e7 pubmed publisher
Menger M, Merscher B, Scheuer C, Braun B, Herath S, Rollmann M, et al. Amlodipine accelerates bone healing in a stable closed femoral fracture model in mice. Eur Cell Mater. 2021;41:592-602 pubmed publisher
Feng D, Ngov C, Henley N, Boufaied N, Gerarduzzi C. Characterization of Matricellular Protein Expression Signatures in Mechanistically Diverse Mouse Models of Kidney Injury. Sci Rep. 2019;9:16736 pubmed publisher
Imhof B, Jemelin S, Ballet R, Vesin C, Schapira M, Karaca M, et al. CCN1/CYR61-mediated meticulous patrolling by Ly6Clow monocytes fuels vascular inflammation. Proc Natl Acad Sci U S A. 2016;113:E4847-56 pubmed publisher
product information
master code :
AF4055
SKU :
AF4055
product name :
Mouse Cyr61/CCN1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse Cyr61/CCN1 Antibody from R&D Systems is a sheep polyclonal antibody to Cyr61/CCN1. This antibody reacts with mouse. The Mouse Cyr61/CCN1 Antibody has been validated for the following applications: Western Blot,Immunoprecipitation,Neutralization,Direct ELISA,Immunohistochemistry-Frozen,Immunohistochemistry,Simple Western.
target :
Cyr61/CCN1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Sheep
immunogen :
E. coli -derived recombinant mouse Cyr61/CCN1, Asp176-Gly281, Accession # NP_034646
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse Cyr61/CCN1 in direct ELISAs and Western blots. In direct ELISAs, this antibody shows approximately 10% cross-reactivity with recombinant human Cyr61/CCN1.
gene symbol :
CYR61
top caption :
Detection of Mouse Cyr61/CCN1 antibody by Western Blot.
accessionNumbers :
NP_034646
applications :
Western Blot,Immunoprecipitation,Neutralization,Direct ELISA,Immunohistochemistry-Frozen,Immunohistochemistry,Simple Western
USD :
479 USD
alt names :
CCN family member 1, CCN1, CCN1IGF-binding protein 10, Cysteine-rich angiogenic inducer 61, cysteine-rich, angiogenic inducer, 61, GIG1, GIG1cysteine-rich heparin-binding protein 61, IBP-10, IGFBP-10, IGFBP10cysteine-rich, anigogenic inducer, 61, Insulin-like growth factor-binding protein 10, protein CYR61, Protein GIG1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.