product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Rat Brevican Antibody
catalog :
AF4009
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 11
Reference
Miguel Hidalgo J, Hearn E, Moulana M, Saleem K, Clark A, Holmes M, et al. Reduced length of nodes of Ranvier and altered proteoglycan immunoreactivity in prefrontal white matter in major depressive disorder and chronically stressed rats. Sci Rep. 2023;13:16419 pubmed publisher
Ueno H, Takahashi Y, Murakami S, Wani K, Miyazaki T, Matsumoto Y, et al. Component-specific reduction in perineuronal nets in senescence-accelerated mouse strains. IBRO Neurosci Rep. 2023;14:111-121 pubmed publisher
H xf6 hn L, Hu xdf ler W, Richter A, Smalla K, Birkl Toeglhofer A, Birkl C, et al. Extracellular Matrix Changes in Subcellular Brain Fractions and Cerebrospinal Fluid of Alzheimer's Disease Patients. Int J Mol Sci. 2023;24: pubmed publisher
Ritok A, Kiss P, Zaher A, Wolf E, Ducza L, Bacskai T, et al. Distribution and postnatal development of chondroitin sulfate proteoglycans in the perineuronal nets of cholinergic motoneurons innervating extraocular muscles. Sci Rep. 2022;12:21606 pubmed publisher
Hu xdf ler W, H xf6 hn L, Stolz C, Vielhaber S, Garz C, Schmitt F, et al. Brevican and Neurocan Cleavage Products in the Cerebrospinal Fluid - Differential Occurrence in ALS, Epilepsy and Small Vessel Disease. Front Cell Neurosci. 2022;16:838432 pubmed publisher
Asega A, Menezes M, Trevisan Silva D, Cajado Carvalho D, Bertholim L, Oliveira A, et al. Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases. Sci Rep. 2020;10:12912 pubmed publisher
Hunyadi A, Gaál B, Matesz C, Mészár Z, Morawski M, Reimann K, et al. Distribution and classification of the extracellular matrix in the olfactory bulb. Brain Struct Funct. 2020;225:321-344 pubmed publisher
Pearson C, Solano A, Tilve S, Mencio C, Martin K, Geller H. Spatiotemporal distribution of chondroitin sulfate proteoglycans after optic nerve injury in rodents. Exp Eye Res. 2020;190:107859 pubmed publisher
Ueno H, Suemitsu S, Murakami S, Kitamura N, Wani K, Matsumoto Y, et al. Layer-specific expression of extracellular matrix molecules in the mouse somatosensory and piriform cortices. IBRO Rep. 2019;6:1-17 pubmed publisher
Irvine S, Kwok J. Perineuronal Nets in Spinal Motoneurones: Chondroitin Sulphate Proteoglycan around Alpha Motoneurones. Int J Mol Sci. 2018;19: pubmed publisher
Ueno H, Suemitsu S, Okamoto M, Matsumoto Y, Ishihara T. Sensory experience-dependent formation of perineuronal nets and expression of Cat-315 immunoreactive components in the mouse somatosensory cortex. Neuroscience. 2017;355:161-174 pubmed publisher
product information
master code :
AF4009
SKU :
AF4009
product name :
Human/Rat Brevican Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Rat Brevican Antibody from R&D Systems is a sheep polyclonal antibody to Brevican. This antibody reacts with human,mouse,rat,transgenic mouse. The Human/Rat Brevican Antibody has been validated for the following applications: Immunohistochemistry,ELISA Development,Western Blot,Immunohistochemistry-Frozen,Immunoprecipitation,Immunocytochemistry.
target :
Brevican
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Sheep
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Brevican, Asp23-Pro911, Accession # AAH27971
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human Brevican in direct ELISAs and Western blots. In direct ELISAs, less than 20% cross-reactivity with recombinant mouse Brevican is observed.
gene symbol :
BCAN
top caption :
Detection of Human Brevican antibody by Western Blot.
accessionNumbers :
AAH27971
applications :
ELISA Development,Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunoprecipitation,Immunocytochemistry
USD :
479 USD
alt names :
ALPBRE, BCAN, BEHAB, BEHABbrevican core protein, Brain-enriched hyaluronan-binding protein, brevican, Chondroitin sulfate proteoglycan 7, chondroitin sulfate proteoglycan BEHAB, chondroitin sulfate proteoglycan BEHAB/brevican, CSPG7, CSPG7brevican proteoglycan, MGC13038
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.