Human/Mouse/Rat Phospho-PP2A (Y307), Catalytic Subunit Antibody

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat Phospho-PP2A (Y307), Catalytic Subunit Antibody

catalog :

AF3989

quantity :

100 ug (also 25 ug)

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, neutralization

more info or order :

R&D Systems product webpage

citations: 9

Reference
Suryawan A, Rudar M, Naberhuis J, Fiorotto M, Davis T. Preterm birth alters the feeding-induced activation of Akt signaling in the muscle of neonatal piglets. Pediatr Res. 2023;93:1891-1898 pubmed publisher
Chang Y, Yao Y, Ma R, Wang Z, Hu J, Wu Y, et al. Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice. Front Neurosci. 2021;15:620176 pubmed publisher
Qiao Y, Zhou Y, Song C, Zhang X, Zou Y. MID1 and MID2 regulate cell migration and epithelial-mesenchymal transition via modulating Wnt/β-catenin signaling. Ann Transl Med. 2020;8:1021 pubmed publisher
Frohner I, Mudrak I, Schüchner S, Anrather D, Hartl M, Sontag J, et al. PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation. Cell Rep. 2020;30:3171-3182.e6 pubmed publisher
Mazhar S, Leonard D, Sosa A, Schlatzer D, Thomas D, Narla G. Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr307 on PP2Ac. Cell Rep. 2020;30:3164-3170.e3 pubmed publisher
Kawai H, Matsushita H, Suzuki R, Kitamura Y, Ogawa Y, Kawada H, et al. Overcoming Tyrosine Kinase Inhibitor Resistance in Transformed Cell Harboring SEPT9-ABL1 Chimeric Fusion Protein. Neoplasia. 2019;21:788-801 pubmed publisher
Sagrillo Fagundes L, Bienvenue Pariseault J, Vaillancourt C. Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells. PLoS ONE. 2019;14:e0202458 pubmed publisher
Liu P, Chen X, Zhou H, Wang L, Zhang Z, Ren X, et al. The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer-Like Pathological Changes In Vitro. Oxid Med Cell Longev. 2018;2018:2025914 pubmed publisher
Huang X, Wang J, Chen X, Liu P, Wang S, Song F, et al. The Prenylflavonoid Xanthohumol Reduces Alzheimer-Like Changes and Modulates Multiple Pathogenic Molecular Pathways in the Neuro2a/APPswe Cell Model of AD. Front Pharmacol. 2018;9:199 pubmed publisher

product information

master code :

AF3989

SKU :

AF3989

product name :

Human/Mouse/Rat Phospho-PP2A (Y307), Catalytic Subunit Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat Phospho-PP2A (Y307), Catalytic Subunit Antibody from R&D Systems is a rabbit polyclonal antibody to PP2A alpha. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat Phospho-PP2A (Y307), Catalytic Subunit Antibody has been validated for the following applications: Western Blot,Neutralization.

target :

PP2A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Phosphopeptide containing human PP2A Y307 site

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human, mouse, and rat PP2A when phosphorylated at Y307. The antigen is identical to the PP4 Y305 phosphorylation site.

gene symbol :

PPP2CA

top caption :

Detection of Human Phospho-PP2A (Y307), Catalytic Subunit antibody by Western Blot.

applications :

Western Blot,Neutralization

USD :

409 USD

alt names :

EC 3.1.3.16, PP2A-alpha, PP2Ac, PP2CA, PP2Calpha, PPP2CA, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform, protein phosphatase 2, catalytic subunit, alpha isozyme, protein phosphatase 2A catalytic subunit, alpha isoform, Replication protein C, RP-C, serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage