Human/Mouse Desmin Antibody | R&D Systems AF3844 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse Desmin Antibody

catalog :

AF3844

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 26

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 2 ug/ml; loading ...; fig 4c	Williams H, Wadey K, Frankow A, Blythe H, Forbes T, Johnson J, et al. Aneurysm severity is suppressed by deletion of CCN4. J Cell Commun Signal. 2021;15:421-432 pubmed publisher
	Quach H, Farrell S, Wu M, Kanagarajah K, Leung J, Xu X, et al. Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity. Nat Commun. 2024;15:5898 pubmed publisher
	Khanal S, Liu Y, Bamidele A, Wixom A, Washington A, Jalan Sakrikar N, et al. Glycolysis in hepatic stellate cells coordinates fibrogenic extracellular vesicle release spatially to amplify liver fibrosis. Sci Adv. 2024;10:eadn5228 pubmed publisher
	Barbeau S, Semprez F, Dobbertin A, Merriadec L, Roussange F, Eymard B, et al. Molecular Analysis of a Congenital Myasthenic Syndrome Due to a Pathogenic Variant Affecting the C-Terminus of ColQ. Int J Mol Sci. 2023;24: pubmed publisher
	He S, Guo Z, Zhou M, Wang H, Zhang Z, Shi M, et al. Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing. Cell Stem Cell. 2023;30:1549-1558.e5 pubmed publisher
	Li L, Feng Y, Zhang J, Zhang Q, Ren J, Sun C, et al. Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy. Cell Commun Signal. 2022;20:115 pubmed publisher
	Ceci L, Chen L, Baiocchi L, Wu N, Kennedy L, Carpino G, et al. Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model. Cell Mol Gastroenterol Hepatol. 2022;14:877-904 pubmed publisher
	Olmsted Z, Paluh J. A combined human gastruloid model of cardiogenesis and neurogenesis. iScience. 2022;25:104486 pubmed publisher
	Sun D, Zhan Z, Zeng R, Liu X, Wang B, Yang F, et al. Long-term and potent IOP-lowering effect of IκBα-siRNA in a nonhuman primate model of chronic ocular hypertension. iScience. 2022;25:104149 pubmed publisher
	Ben Dhaou C, Mandi K, Frye M, Acheampong A, Radi A, De Becker B, et al. Chemerin regulates normal angiogenesis and hypoxia-driven neovascularization. Angiogenesis. 2022;25:159-179 pubmed publisher
	Brodehl A, Hain C, Flottmann F, Ratnavadivel S, Gaertner A, Klauke B, et al. The Desmin Mutation DES-c.735G>C Causes Severe Restrictive Cardiomyopathy by Inducing In-Frame Skipping of Exon-3. Biomedicines. 2021;9: pubmed publisher
	Su Y, Bamodu O, Su I, Pikatan N, Fong I, Lee W, et al. Combined Treatment with Acalabrutinib and Rapamycin Inhibits Glioma Stem Cells and Promotes Vascular Normalization by Downregulating BTK/mTOR/VEGF Signaling. Pharmaceuticals (Basel). 2021;14: pubmed publisher
	Bruijn L, van den Akker B, van Rhijn C, Hamming J, Lindeman J. Extreme Diversity of the Human Vascular Mesenchymal Cell Landscape. J Am Heart Assoc. 2020;9:e017094 pubmed publisher
	Hara Chikuma M, Tanaka M, Verkman A, Yasui M. Inhibition of aquaporin-3 in macrophages by a monoclonal antibody as potential therapy for liver injury. Nat Commun. 2020;11:5666 pubmed publisher
	Lee Y, Leslie J, Yang Y, Ding L. Hepatic stellate and endothelial cells maintain hematopoietic stem cells in the developing liver. J Exp Med. 2021;218: pubmed publisher
	Deng M, Xu L, Xie X, Sheng X, Zou Z, Yao M. Downregulation of syndecan‑1 expression induces activation of hepatic stellate cells via the TGF‑β1/Smad3 signaling pathway. Mol Med Rep. 2019;20:368-374 pubmed publisher
	Huijbers E, van der Werf I, Faber L, Sialino L, van der Laan P, Holland H, et al. Targeting Tumor Vascular CD99 Inhibits Tumor Growth. Front Immunol. 2019;10:651 pubmed publisher
	Han X, Wang Y, Pu W, Huang X, Qiu L, Li Y, et al. Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration. Stem Cell Reports. 2019;12:624-638 pubmed publisher
	Niu F, Liao K, Hu G, Sil S, Callen S, Guo M, et al. Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS. J Cell Biol. 2019;218:700-721 pubmed publisher
	Dubrac A, Künzel S, Künzel S, Li J, Chandran R, Martin K, et al. NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy. Nat Commun. 2018;9:3463 pubmed publisher
	Szot C, Saha S, Zhang X, Zhu Z, Hilton M, Morris K, et al. Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release. J Clin Invest. 2018;128:2927-2943 pubmed publisher
	Lee H, Choi J, Son T, Wee H, Bae S, Seo J, et al. Altered AKAP12 expression in portal fibroblasts and liver sinusoids mediates transition from hepatic fibrogenesis to fibrosis resolution. Exp Mol Med. 2018;50:48 pubmed publisher
	Lyon C, Williams H, Bianco R, Simmonds S, Brown B, Wadey K, et al. Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression. Sci Rep. 2017;7:17342 pubmed publisher
	Kloepper J, Riedemann L, Amoozgar Z, Seano G, Susek K, Yu V, et al. Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival. Proc Natl Acad Sci U S A. 2016;113:4476-81 pubmed publisher
	Peterson T, Kirkpatrick N, Huang Y, Farrar C, Marijt K, Kloepper J, et al. Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages. Proc Natl Acad Sci U S A. 2016;113:4470-5 pubmed publisher
	Liu Q, Yang R, Huang X, Zhang H, He L, Zhang L, et al. Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes. Cell Res. 2016;26:119-30 pubmed publisher

product information

master code :

AF3844

SKU :

AF3844

product name :

Human/Mouse Desmin Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse Desmin Antibody from R&D Systems is a goat polyclonal antibody to Desmin. This antibody reacts with human,mouse,transgenic mouse. The Human/Mouse Desmin Antibody has been validated for the following applications: Immunocytochemistry,Immunohistochemistry,Bioassay,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.

target :

Desmin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human Desmin, Val261-Leu470, Accession # P17661

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Transgenic Mouse

specificity :

Detects human and mouse Desmin.

gene symbol :

DES

top caption :

Desmin antibody in Human Heart by Immunohistochemistry (IHC-P).

accessionNumbers :

P17661

applications :

Immunocytochemistry,Immunohistochemistry,Bioassay,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen

USD :

499 USD

alt names :

CMD1I, CMD1IFLJ41013, CSM1, CSM2, DES, desmin, FLJ12025, FLJ39719, FLJ41793, intermediate filament protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage