product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Aminopeptidase LRAP/ERAP2 Antibody
catalog :
AF3830
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 9
Reference
S xe6 terstad S, xd8 stvik A, Hansen M, Bruland T, van Beelen Granlund A. The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response. J Transl Med. 2024;22:750 pubmed publisher
Temponeras I, Stamatakis G, Samiotaki M, Georgiadis D, Pratsinis H, Panayotou G, et al. ERAP2 Inhibition Induces Cell-Surface Presentation by MOLT-4 Leukemia Cancer Cells of Many Novel and Potentially Antigenic Peptides. Int J Mol Sci. 2022;23: pubmed publisher
Venema W, Hiddingh S, De Boer J, Claas F, Mulder A, den Hollander A, et al. ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29. Front Immunol. 2021;12:634441 pubmed publisher
Jiang P, Veenstra R, Seitz A, Nolte I, Hepkema B, Visser L, et al. Interaction between ERAP Alleles and HLA Class I Types Support a Role of Antigen Presentation in Hodgkin Lymphoma Development. Cancers (Basel). 2021;13: pubmed publisher
Saulle I, Vanetti C, Goglia S, Vicentini C, Tombetti E, Garziano M, et al. A New ERAP2/Iso3 Isoform Expression Is Triggered by Different Microbial Stimuli in Human Cells. Could It Play a Role in the Modulation of SARS-CoV-2 Infection?. Cells. 2020;9: pubmed publisher
Seamon K, Kurlak L, Warthan M, Stratikos E, Strauss J, Mistry H, et al. The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia. Front Immunol. 2020;11:396 pubmed publisher
Koumantou D, Barnea E, Martin Esteban A, Maben Z, Papakyriakou A, Mpakali A, et al. Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1). Cancer Immunol Immunother. 2019;: pubmed publisher
Wu C, Lin J, Chen J, Chang C, Weng H, Hsueh C, et al. Integrated analysis of fine-needle-aspiration cystic fluid proteome, cancer cell secretome, and public transcriptome datasets for papillary thyroid cancer biomarker discovery. Oncotarget. 2018;9:12079-12100 pubmed publisher
Warthan M, Washington S, Franzese S, Ramus R, Kim K, York T, et al. The role of endoplasmic reticulum aminopeptidase 2 in modulating immune detection of choriocarcinoma. Biol Reprod. 2018;98:309-322 pubmed publisher
product information
master code :
AF3830
SKU :
AF3830
product name :
Human Aminopeptidase LRAP/ERAP2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Aminopeptidase LRAP/ERAP2 Antibody from R&D Systems is a goat polyclonal antibody to Aminopeptidase LRAP/ERAP2. This antibody reacts with human. The Human Aminopeptidase LRAP/ERAP2 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunoprecipitation.
target :
Aminopeptidase LRAP/ERAP2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Aminopeptidase LRAP/ERAP2, Ala56-Thr960, Accession # Q6P179
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human Aminopeptidase LRAP/ERAP2 in direct ELISAs and Western blots.
gene symbol :
ERAP2
top caption :
Detection of Human Aminopeptidase LRAP/ERAP2 by Western Blot
accessionNumbers :
Q6P179
applications :
Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunoprecipitation
USD :
469 USD
alt names :
EC 3.4.11, EC 3.4.11.3, endoplasmic reticulum aminopeptidase 2, ERAP2, FLJ23633, FLJ23701, FLJ23807, Leukocyte-derived arginine aminopeptidase, LRAPL-RAPEC 3.4.11.-
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.