product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse M-CSF R/CD115 Antibody
catalog :
AF3818
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:750; loading ...; fig 1c
Pons V, Lévesque P, Plante M, Rivest S. Conditional genetic deletion of CSF1 receptor in microglia ameliorates the physiopathology of Alzheimer's disease. Alzheimers Res Ther. 2021;13:8 pubmed publisher
Li X, Hu B, Guan X, Wang Z, Zhou Y, Sun H, et al. Minocycline protects against microgliopathy in a Csf1r haplo-insufficient mouse model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP). J Neuroinflammation. 2023;20:134 pubmed publisher
Czepielewski R, Erlich E, Onufer E, Young S, Saunders B, Han Y, et al. Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor. Immunity. 2021;54:2795-2811.e9 pubmed publisher
Zelic M, Pontarelli F, Woodworth L, Zhu C, Mahan A, Ren Y, et al. RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis. Cell Rep. 2021;35:109112 pubmed publisher
Nishida D, Arai A, Zhao L, Yang M, Nakamichi Y, Horibe K, et al. RANKL/OPG ratio regulates odontoclastogenesis in damaged dental pulp. Sci Rep. 2021;11:4575 pubmed publisher
Ibrahim A, Moss M, Gray Z, Rojo M, Burke C, Schwertfeger K, et al. Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion. Front Oncol. 2020;10:569985 pubmed publisher
Wang P, Yim A, Kim K, Avey D, Czepielewski R, Colonna M, et al. Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia. Nat Commun. 2020;11:2552 pubmed publisher
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, et al. Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth. Cell Rep. 2020;31:107628 pubmed publisher
Marsters C, Nesan D, Far R, Klenin N, Pittman Q, Kurrasch D. Embryonic microglia influence developing hypothalamic glial populations. J Neuroinflammation. 2020;17:146 pubmed publisher
Pons V, Laflamme N, Pr xe9 fontaine P, Rivest S. Role of Macrophage Colony-Stimulating Factor Receptor on the Proliferation and Survival of Microglia Following Systemic Nerve and Cuprizone-Induced Injuries. Front Immunol. 2020;11:47 pubmed publisher
product information
brand :
R&D Systems
master code :
AF3818
SKU :
AF3818
product name :
Mouse M-CSF R/CD115 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse M-CSF R/CD115 Antibody from R&D Systems is a sheep polyclonal antibody to M-CSFR/CD115. This antibody reacts with mouse. The Mouse M-CSF R/CD115 Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot.
target :
M-CSF R/CD115
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Sheep
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse M-CSF R/CD115, Ala20-Ser511, Accession # P09581
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse M-CSF R/CD115 in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant human M-CSF R/CD115 is observed.
gene symbol :
CSF1R
top caption :
M-CSF R/CD115 antibody in Mouse Splenocytes by Immunocytochemistry (ICC).
accessionNumbers :
P09581
applications :
Western Blot,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
499 USD
alt names :
CD115, CD115 antigen, C-FMS, colony stimulating factor 1 receptor, CSF1R, CSF-1-R, CSFR, EC 2.7.10.1, FMS proto-oncogene, FMSFIM2, macrophage colony stimulating factor I receptor, macrophage colony-stimulating factor 1 receptor, McDonough feline sarcoma viral (v-fms) oncogene homolog, MCSFR, M-CSFR, Proto-oncogene c-Fms
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.