Human/Mouse/Rat Glutathione Peroxidase 1/GPX1 Antibody | R&D Systems AF3798 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat Glutathione Peroxidase 1/GPX1 Antibody

catalog :

AF3798

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

R&D Systems product webpage

citations: 17

Reference
Toh P, Seale L, Berry M, Torres D. Prolonged maternal exposure to glucocorticoids alters selenoprotein expression in the developing brain. Front Mol Neurosci. 2023;16:1115993 pubmed publisher
Evke S, Lin Q, MELENDEZ J, Begley T. Epitranscriptomic Reprogramming Is Required to Prevent Stress and Damage from Acetaminophen. Genes (Basel). 2022;13: pubmed publisher
Minati M, Libert M, Dahou H, Jacquemin P, Assi M. N-Acetylcysteine Reduces the Pro-Oxidant and Inflammatory Responses during Pancreatitis and Pancreas Tumorigenesis. Antioxidants (Basel). 2021;10: pubmed publisher
Kilonzo V, Sasuclark A, Torres D, Coyle C, Pilat J, Williams C, et al. Juvenile Selenium Deficiency Impairs Cognition, Sensorimotor Gating, and Energy Homeostasis in Mice. Front Nutr. 2021;8:667587 pubmed publisher
Zhang L, Zhang B, Wang L, Lou M, Shen Y. Huanglian-Houpo drug combination ameliorates H1N1-induced mouse pneumonia via cytokines, antioxidant factors and TLR/MyD88/NF-κB signaling pathways. Exp Ther Med. 2021;21:428 pubmed publisher
Khanh V, Yamashita T, Ohneda K, Tokunaga C, Kato H, Osaka M, et al. Rejuvenation of mesenchymal stem cells by extracellular vesicles inhibits the elevation of reactive oxygen species. Sci Rep. 2020;10:17315 pubmed publisher
Chu Y, Lan R, Huang R, Feng H, Kumar R, Dayal S, et al. Glutathione peroxidase-1 overexpression reduces oxidative stress, and improves pathology and proteome remodeling in the kidneys of old mice. Aging Cell. 2020;19:e13154 pubmed publisher
Leonardi A, Kovalchuk N, Yin L, Endres L, Evke S, Nevins S, et al. The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene. Epigenetics. 2020;15:1121-1138 pubmed publisher
Lee M, Leonardi A, Begley T, Melendez J. Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming☆. Redox Biol. 2020;28:101375 pubmed publisher
Li G, Chan Y, Sukjamnong S, Anwer A, Vindin H, Padula M, et al. A Mitochondrial Specific Antioxidant Reverses Metabolic Dysfunction and Fatty Liver Induced by Maternal Cigarette Smoke in Mice. Nutrients. 2019;11: pubmed publisher
Cowley P, Wang G, Swigart P, Raghunathan A, Reddy N, Dulam P, et al. Reversal of right ventricular failure by chronic α1A-subtype adrenergic agonist therapy. Am J Physiol Heart Circ Physiol. 2019;316:H224-H232 pubmed publisher
Youssef P, Chami B, Lim J, Middleton T, Sutherland G, Witting P. Evidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer's disease. Sci Rep. 2018;8:11553 pubmed publisher
Lau W, Khazaeli M, Savoj J, Manekia K, Bangash M, Thakurta R, et al. Dietary tetrahydrocurcumin reduces renal fibrosis and cardiac hypertrophy in 5/6 nephrectomized rats. Pharmacol Res Perspect. 2018;6:e00385 pubmed publisher
Coleman V, Sa Nguanmoo P, Koenig J, Schulz T, Grune T, Klaus S, et al. Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling. Sci Rep. 2018;8:2446 pubmed publisher
Ogawa Wong A, Hashimoto A, Ha H, Pitts M, Seale L, Berry M. Sexual Dimorphism in the Selenocysteine Lyase Knockout Mouse. Nutrients. 2018;10: pubmed publisher
Jing W, Vaziri N, Nunes A, Suematsu Y, Farzaneh T, Khazaeli M, et al. LCZ696 (Sacubitril/valsartan) ameliorates oxidative stress, inflammation, fibrosis and improves renal function beyond angiotensin receptor blockade in CKD. Am J Transl Res. 2017;9:5473-5484 pubmed
Shimada K, Skouta R, Kaplan A, Yang W, Hayano M, Dixon S, et al. Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nat Chem Biol. 2016;12:497-503 pubmed publisher

product information

master code :

AF3798

SKU :

AF3798

product name :

Human/Mouse/Rat Glutathione Peroxidase 1/GPX1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat Glutathione Peroxidase 1/GPX1 Antibody from R&D Systems is a goat polyclonal antibody to Glutathione Peroxidase 1/GPX1. This antibody reacts with human,mouse,rat,transgenic mouse,transgenic rat. The Human/Mouse/Rat Glutathione Peroxidase 1/GPX1 Antibody has been validated for the following applications: Western Blot,Simple Western,Immunohistochemistry,Knockout Validated.

target :

Glutathione Peroxidase 1/GPX1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human Glutathione Peroxidase 1, Gly48-Ala201, Accession # P07203

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat,Transgenic Mouse

specificity :

Detects endogenous human, mouse, and rat GPX1. In Western blots, this antibody shows no cross-reactivity with recombinant human GPX2 or GPX3.

gene symbol :

GPX1

Antibody validation :

Knockout/Knockdown

top caption :

Glutathione Peroxidase 1/GPX1 antibody in Rat Liver by Immunohistochemistry (IHC-Fr).

accessionNumbers :

P07203

applications :

Simple Western,Western Blot,Immunohistochemistry,Knockout Validated

USD :

479 USD

alt names :

Cellular glutathione peroxidase, CGPx, EC 1.11.1, EC 1.11.1.9, glutathione peroxidase 1, GPx-1, GPX1, GSHPx-1, GSHPX1, MGC14399, MGC88245

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage