product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human SCP3/SYCP3 Antibody
catalog :
AF3750
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:25; loading ...; fig 4a
Ji Z, Yao C, Yang C, Huang C, Zhao L, Han X, et al. Novel Hemizygous Mutations of TEX11 Cause Meiotic Arrest and Non-obstructive Azoospermia in Chinese Han Population. Front Genet. 2021;12:741355 pubmed publisher
Shao Q, Zhang Y, LIU Y, Shang Y, Li S, Liu L, et al. ATF7IP2, a meiosis-specific partner of SETDB1, is required for proper chromosome remodeling and crossover formation during spermatogenesis. Cell Rep. 2023;42:112953 pubmed publisher
You X, Li T, Cui Y, Liu W, Cheng Z, Zeng W, et al. Retinoic acid-induced differentiation of porcine prospermatogonia in vitro. Theriogenology. 2023;198:344-355 pubmed publisher
Abe H, Yeh Y, Munakata Y, Ishiguro K, Andreassen P, Namekawa S. Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation. Nat Commun. 2022;13:7212 pubmed publisher
Huang Y, Tian R, Xu J, Ji Z, Zhang Y, Zhao L, et al. Novel copy number variations within SYCE1 caused meiotic arrest and non-obstructive azoospermia. BMC Med Genomics. 2022;15:137 pubmed publisher
Liu R, Liu Z, Guo M, Zeng W, Zheng Y. SETDB1 Regulates Porcine Spermatogonial Adhesion and Proliferation through Modulating MMP3/10 Transcription. Cells. 2022;11: pubmed publisher
Li P, Ji Z, Zhi E, Zhang Y, Han S, Zhao L, et al. Novel bi-allelic MSH4 variants causes meiotic arrest and non-obstructive azoospermia. Reprod Biol Endocrinol. 2022;20:21 pubmed publisher
Yao C, Yang C, Zhao L, Li P, Tian R, Chen H, et al. Bi-allelic SHOC1 loss-of-function mutations cause meiotic arrest and non-obstructive azoospermia. J Med Genet. 2021;58:679-686 pubmed publisher
Slotman J, Paul M, Carofiglio F, de Gruiter H, Vergroesen T, Koornneef L, et al. Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase. PLoS Genet. 2020;16:e1008595 pubmed publisher
Brandsma I, Sato K, van Rossum Fikkert S, van Vliet N, Sleddens E, Reuter M, et al. HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis. Cell Rep. 2019;27:3790-3798.e7 pubmed publisher
Carofiglio F, Sleddens Linkels E, Wassenaar E, Inagaki A, van Cappellen W, Grootegoed J, et al. Repair of exogenous DNA double-strand breaks promotes chromosome synapsis in SPO11-mutant mouse meiocytes, and is altered in the absence of HORMAD1. DNA Repair (Amst). 2018;63:25-38 pubmed publisher
product information
master code :
AF3750
SKU :
AF3750
product name :
Human SCP3/SYCP3 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human SCP3/SYCP3 Antibody from R&D Systems is a goat polyclonal antibody to SCP3/SYCP3. This antibody reacts with human,mouse,porcine. The Human SCP3/SYCP3 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunocytochemistry.
target :
SCP3/SYCP3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human SCP3/SYCP3, Met1-Phe236, Accession # Q8IZU3
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Porcine
specificity :
Detects human SCP3/SYCP3 in direct ELISAs and Western blots.
gene symbol :
SYCP3
accessionNumbers :
Q8IZU3
applications :
Western Blot,Immunohistochemistry,Immunocytochemistry
USD :
499 USD
alt names :
COR1, MGC71888, SCP3, SCP-3, SCP3 chromosome 3 open reading frame 8, SCP3 COR1, SYCP3, synaptonemal complex protein 3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.