Human TRAIL/TNFSF10 Antibody | R&D Systems AF375 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TRAIL/TNFSF10 Antibody

catalog :

AF375

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Yoon Y, Kim C, Kim M, Baik S, Jung P, Eom Y. Interferon-β Overexpression in Adipose Tissue-Derived Stem Cells Induces HepG2 and Macrophage Cell Death in Liver Tumor Organoids via Induction of TNF-Related Apoptosis-Inducing Ligand Expression. Int J Mol Sci. 2024;25: pubmed publisher
Luo Y, Hao H, Wang Z, Ong C, Dutcher R, Xu Y, et al. Heparan sulfate promotes TRAIL-induced tumor cell apoptosis. bioRxiv. 2023;: pubmed publisher
An Y, Jeon J, Sun L, Derakhshan A, Chen J, Carlson S, et al. Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas. Sci Rep. 2021;11:6392 pubmed publisher
Sanmarco L, Wheeler M, Gutiérrez Vázquez C, Polonio C, Linnerbauer M, Pinho Ribeiro F, et al. Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes. Nature. 2021;: pubmed publisher
Byun C, Hwang S, Woo S, Kim M, Lee J, Lee J, et al. Adipose Tissue-Derived Mesenchymal Stem Cells Suppress Growth of Huh7 Hepatocellular Carcinoma Cells via Interferon (IFN)-β-Mediated JAK/STAT1 Pathway in vitro. Int J Med Sci. 2020;17:609-619 pubmed publisher
Li T, Yang Y, Song H, Li H, Cui A, Liu Y, et al. Activated NK cells kill hepatic stellate cells via p38/PI3K signaling in a TRAIL-involved degranulation manner. J Leukoc Biol. 2019;105:695-704 pubmed publisher

product information

master code :

AF375

SKU :

AF375

product name :

Human TRAIL/TNFSF10 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human TRAIL/TNFSF10 Antibody from R&D Systems is a goat polyclonal antibody to TRAIL/TNFSF10. This antibody reacts with canine,feline,human. The Human TRAIL/TNFSF10 Antibody has been validated for the following applications: Bioassay,Flow Cytometry,Western Blot,Neutralization,Affinity Purification,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry.

target :

TRAIL/TNFSF10

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TRAIL/TNFSF10, Thr95-Gly281, Accession # P50591

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Canine,Feline,Human

specificity :

Detects human TRAIL/TNFSF10 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse TRAIL is observed.

gene symbol :

TNFSF10

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Human TRAIL/TNFSF10 antibody by Western Blot.

accessionNumbers :

P50591

applications :

Bioassay,Flow Cytometry,Western Blot,Neutralization,Affinity Purification,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

489 USD

alt names :

Apo-2 ligand, APO2L, Apo-2Ltumor necrosis factor (ligand) family, member 10, APO2Ltumor necrosis factor apoptosis-inducing ligand splice variant delta, CD253, CD253 antigen, Protein TRAIL, TL2, TNF-related apoptosis-inducing ligand, TNFSF10, TRAILTNF-related apoptosis inducing ligand TRAIL, tumor necrosis factor (ligand) superfamily, member 10, tumor necrosis factor ligand superfamily member 10

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage