product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TrkC Antibody
catalog :
AF373
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:500; fig 2c
Fattahi F, Steinbeck J, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, et al. Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. Nature. 2016;531:105-9 pubmed publisher
Saito Diaz K, James C, Patel A, Zeltner N. Isolation of human pluripotent stem cell-derived sensory neuron subtypes by immunopanning. Front Cell Dev Biol. 2023;11:1101423 pubmed publisher
Badiola Mateos M, Osaki T, Kamm R, Samitier J. In vitro modelling of human proprioceptive sensory neurons in the neuromuscular system. Sci Rep. 2022;12:21318 pubmed publisher
Ateaque S, Merkouris S, Wyatt S, Allen N, Xie J, DiStefano P, et al. Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC. J Neurochem. 2022;161:463-477 pubmed publisher
Eze U, Bhaduri A, Haeussler M, Nowakowski T, Kriegstein A. Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia. Nat Neurosci. 2021;24:584-594 pubmed publisher
Maury Y, Côme J, Piskorowski R, Salah Mohellibi N, Chevaleyre V, Peschanski M, et al. Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes. Nat Biotechnol. 2015;33:89-96 pubmed publisher
product information
master code :
AF373
SKU :
AF373
product name :
Human TrkC Antibody
unit size :
100 ug (also 25 ug)
description :
The Human TrkC Antibody from R&D Systems is a goat polyclonal antibody to TrkC. This antibody reacts with human. The Human TrkC Antibody has been validated for the following applications: Immunocytochemistry,Functional Assay,Immunohistochemistry,Flow Cytometry,Western Blot,Simple Western,Blockade of Receptor-ligand Interaction,CyTOF-ready.
target :
TrkC
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human TrkC, Cys32-Asp428, Accession # Q96CY4
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human TrkC in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human TrkB is observed.
gene symbol :
NTRK3
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of HAF017 TrkC antibody by Western Blot.
accessionNumbers :
Q96CY4
applications :
Immunocytochemistry,Functional Assay,Immunohistochemistry,Flow Cytometry,Western Blot,Simple Western,Blockade of Receptor-ligand Interaction,CyTOF-ready
USD :
479 USD
alt names :
EC 2.7.10, EC 2.7.10.1, ETS related protein-neurotrophic receptor tyrosine kinase fusion protein, ETV6-NTRK3 fusion, gp145(trkC), GP145-TrkC, Neurotrophic tyrosine kinase receptor type 3, neurotrophic tyrosine kinase, receptor, type 3, NT 3 receptor, NT-3 growth factor receptor, NTRK3, Trk-C, TrkC tyrosine kinase, TRKCneurotrophin 3 receptor, tyrosine kinase receptor C
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.