product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse SCGF/CLEC11a Antibody
catalog :
AF3729
quantity :
100 ug (also 25 ug)
price :
459 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, ELISA, immunohistochemistry
more info or order :
citations: 7
Reference
Fan A, Wu G, Wang J, Lu L, Wang J, Wei H, et al. Inhibition of fibroblast activation protein ameliorates cartilage matrix degradation and osteoarthritis progression. Bone Res. 2023;11:3 pubmed publisher
Gadomski S, Fielding C, Garc xed a Garc xed a A, Korn C, Kapeni C, Ashraf S, et al. A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise. Cell Stem Cell. 2022;29:528-544.e9 pubmed publisher
Zhang J, Cohen A, Shen B, Du L, Tasdogan A, Zhao Z, et al. The effect of parathyroid hormone on osteogenesis is mediated partly by osteolectin. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Wei H, Xu Y, Wang Y, Xu L, Mo C, Li L, et al. Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target. Cell Rep. 2020;33:108252 pubmed publisher
Hu Y, Zhang Y, Ni C, Chen C, Rao S, Yin H, et al. Human umbilical cord mesenchymal stromal cells-derived extracellular vesicles exert potent bone protective effects by CLEC11A-mediated regulation of bone metabolism. Theranostics. 2020;10:2293-2308 pubmed publisher
Ramalingam P, Poulos M, Lazzari E, Gutkin M, Lopez D, Kloss C, et al. Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF. Nat Commun. 2020;11:666 pubmed publisher
Shen B, Vardy K, Hughes P, Tasdogan A, Zhao Z, Yue R, et al. Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass. elife. 2019;8: pubmed publisher
product information
master code :
AF3729
SKU :
AF3729
product name :
Mouse SCGF/CLEC11a Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse SCGF/CLEC11a Antibody from R&D Systems is a goat polyclonal antibody to SCGF/CLEC11a. This antibody reacts with human,mouse. The Mouse SCGF/CLEC11a Antibody has been validated for the following applications: Immunohistochemistry,ELISA (detection),Western Blot.
target :
SCGF/CLEC11a
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse SCGF/CLEC11a, Ala22-Phe328, Accession # O88200
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse SCGF/CLEC11a in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human SCGF is observed.
gene symbol :
Clec11a
accessionNumbers :
O88200
applications :
ELISA (detection),Western Blot,Immunohistochemistry
USD :
459 USD
alt names :
CLEC11a, CLECSF3, LSLCL, P47, SCGF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.