Human/Mouse/Rat Cubilin Antibody | R&D Systems AF3700 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat Cubilin Antibody

catalog :

AF3700

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 7

Reference
x17d u x17e ul S, Kelam N, Racetin A, Kova x10d evi x107 P, Konjevoda S, Filipovi x107 N, et al. Immunoexpression Patterns of Megalin, Cubilin, Caveolin-1, Gipc1 and Dab2IP in the Embryonic and Postnatal Development of the Kidneys in Yotari (Dab1-/-) Mice. Biomedicines. 2024;12: pubmed publisher
Priante G, Ceol M, Gianesello L, Bizzotto D, Braghetta P, Cal xf2 L, et al. Emerging Perspectives on the Rare Tubulopathy Dent Disease: Is Glomerular Damage a Direct Consequence of ClC-5 Dysfunction?. Int J Mol Sci. 2023;24: pubmed publisher
Muto Y, DIXON E, Yoshimura Y, Wu H, Omachi K, Ledru N, et al. Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis. Nat Commun. 2022;13:6497 pubmed publisher
Ungricht R, Guibbal L, Lasbennes M, Orsini V, Beibel M, Waldt A, et al. Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis. Cell Stem Cell. 2022;29:160-175.e7 pubmed publisher
Gianesello L, Ceol M, Bertoldi L, Terrin L, Priante G, Murer L, et al. Genetic Analyses in Dent Disease and Characterization of CLCN5 Mutations in Kidney Biopsies. Int J Mol Sci. 2020;21: pubmed publisher
Fels J, Scharner B, Zarbock R, Zavala Guevara I, Lee W, Barbier O, et al. Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule. Int J Mol Sci. 2019;20: pubmed publisher
Yamaguchi T, Higa N, Okura N, Matsumoto A, Hermawan I, Yamashiro T, et al. Characterizing interactions of Leptospira interrogans with proximal renal tubule epithelial cells. BMC Microbiol. 2018;18:64 pubmed publisher

product information

master code :

AF3700

SKU :

AF3700

product name :

Human/Mouse/Rat Cubilin Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat Cubilin Antibody from R&D Systems is a sheep polyclonal antibody to Cubilin. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat Cubilin Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Frozen,Immunofluorescence,Western Blot,Simple Western.

target :

Cubilin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Sheep

immunogen :

E. coli -derived recombinant human Cubilin, Ser36-Gly126, Accession # O60494

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human Cubilin in direct ELISAs and Western blots.

gene symbol :

CUBN

top caption :

Detection of Human, Mouse, and Rat Cubilin antibody by Western Blot.

accessionNumbers :

O60494

applications :

Immunohistochemistry,Immunohistochemistry-Frozen,Immunofluorescence,Western Blot,Simple Western

USD :

469 USD

alt names :

cubilin, cubilin (intrinsic factor-cobalamin receptor), CUBN, Cubulin, gp280, IFCR, MGA1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage