product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse c-Myc Antibody
catalog :
AF3696
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation
more info or order :
citations: 10
Reference
Wang F, Gao Y, Xue S, Zhao L, Jiang H, Zhang T, et al. SCARB2 drives hepatocellular carcinoma tumor initiating cells via enhanced MYC transcriptional activity. Nat Commun. 2023;14:5917 pubmed publisher
Liang Y, Liu X, Zhou R, Song D, Jiang Y, Xue W. Chaetocin Promotes Osteogenic Differentiation via Modulating Wnt/Beta-Catenin Signaling in Mesenchymal Stem Cells. Stem Cells Int. 2021;2021:8888416 pubmed publisher
Greco C, Cervantes M, Fustin J, Ito K, Ceglia N, Samad M, et al. S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling. Sci Adv. 2020;6: pubmed publisher
Liu X, Wang K, Du H. LncRNA SNHG6 regulating Hedgehog signaling pathway and affecting the biological function of gallbladder carcinoma cells through targeting miR-26b-5p. Eur Rev Med Pharmacol Sci. 2020;24:7598-7611 pubmed publisher
Luo Z, Qing X, Benda C, Huang Z, Zhang M, Huang Y, et al. Nuclear-cytoplasmic shuttling of class IIa histone deacetylases regulates somatic cell reprogramming. Cell Regen (Lond). 2019;8:21-29 pubmed publisher
Itkonen H, Urbanucci A, Martin S, Khan A, Mathelier A, Thiede B, et al. High OGT activity is essential for MYC-driven proliferation of prostate cancer cells. Theranostics. 2019;9:2183-2197 pubmed publisher
Luo J, Yao Y, Ji S, Sun Q, Xu Y, Liu K, et al. PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway. Cancer Cell Int. 2019;19:96 pubmed publisher
Nagasaka M, Tsuzuki K, Ozeki Y, Tokugawa M, Ohoka N, Inoue Y, et al. Lysine-Specific Demethylase 1 (LSD1/KDM1A) Is a Novel Target Gene of c-Myc. Biol Pharm Bull. 2019;42:481-488 pubmed publisher
Seth P, Hsieh P, Jamal S, Wang L, Gygi S, Jain M, et al. Regulation of MicroRNA Machinery and Development by Interspecies S-Nitrosylation. Cell. 2019;176:1014-1025.e12 pubmed publisher
Morrison G, Scognamiglio R, Trumpp A, Smith A. Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification. EMBO J. 2016;35:356-68 pubmed publisher
product information
brand :
R&D Systems
master code :
AF3696
SKU :
AF3696
product name :
Human/Mouse c-Myc Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse c-Myc Antibody from R&D Systems is a goat polyclonal antibody to c-Myc. This antibody reacts with human,mouse. The Human/Mouse c-Myc Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Chromatin Immunoprecipitation (ChIP),Simple Western,Immunocytochemistry,Knockout Validated.
target :
c-Myc
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, Simple Western 20 ug/mL, Immunohistochemistry 5-15 ug/mL, Chromatin Immunoprecipitation (ChIP) 5 ug/5 x 10^6 cells, Immunocytochemistry 5-15 ug/mL, Knockout Validated
host :
Goat
immunogen :
E. coli -derived recombinant human c-Myc, Arg66-Asp201, Accession # P01106
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human c-Myc in direct ELISAs. Detects human and mouse c-Myc in Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) L-Myc and rhN-Myc is observed.
gene symbol :
MYC
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Human c-Myc antibody by Western Blot.
accessionNumbers :
P01106
applications :
Immunohistochemistry,Simple Western,Immunocytochemistry,Knockout Validated,Western Blot,Chromatin Immunoprecipitation (ChIP)
USD :
509 USD
alt names :
avian myelocytomatosis viral oncogene homolog, BHLHE39, bHLHe39MRTL, Class E basic helix-loop-helix protein 39, cMyc, c-Myc, MYC, myc proto-oncogene protein, Myc2, MYCC, myc-related translation/localization regulatory factor, Niard, Nird, Proto-oncogene c-Myc, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog (avian)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.