product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Rat TIM-1/KIM-1/HAVCR Antibody
catalog :
AF3689
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
rat
application :
western blot, ELISA, immunohistochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 25
Reference
Nelson P, Dugbartey G, McFarlane L, McLeod P, Major S, Jiang J, et al. Effect of Sodium Thiosulfate Pre-Treatment on Renal Ischemia-Reperfusion Injury in Kidney Transplantation. Int J Mol Sci. 2024;25: pubmed publisher
Huang J, Caliskan Guzelce E, Gholami S, Gawelek K, Mitchell R, Pojoga L, et al. Effects of Mineralocorticoid Receptor Blockade and Statins on Kidney Injury Marker 1 (KIM-1) in Female Rats Receiving L-NAME and Angiotensin II. Int J Mol Sci. 2023;24: pubmed publisher
Nagayama I, Takayanagi K, Hasegawa H, Maeshima A. Tubule-Derived Follistatin Is Increased in the Urine of Rats with Renal Ischemia and Reflects the Severity of Acute Tubular Damage. Cells. 2023;12: pubmed publisher
Ceja Galicia Z, Garc xed a Arroyo F, Aparicio Trejo O, El Hafidi M, Gonzaga S xe1 nchez G, Le xf3 n Contreras J, et al. Therapeutic Effect of Curcumin on 5/6Nx Hypertriglyceridemia: Association with the Improvement of Renal Mitochondrial β-Oxidation and Lipid Metabolism in Kidney and Liver. Antioxidants (Basel). 2022;11: pubmed publisher
Rinschen M, Palygin O, El Meanawy A, Domingo Almenara X, Palermo A, Dissanayake L, et al. Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension. Nat Commun. 2022;13:4099 pubmed publisher
Yue Y, Yeh J, CHIANG J, Sung P, Chen Y, Liu F, et al. Intrarenal arterial administration of human umbilical cord-derived mesenchymal stem cells effectively preserved the residual renal function of diabetic kidney disease in rat. Stem Cell Res Ther. 2022;13:186 pubmed publisher
Lim J, Jung W, Kim W, Moon K, Sul D. Nephrotoxicity evaluation and proteomic analysis in kidneys of rats exposed to thioacetamide. Sci Rep. 2022;12:6837 pubmed publisher
Krohn P, Rega L, Harvent M, Festa B, Taranta A, Luciani A, et al. Multisystem involvement, defective lysosomes and impaired autophagy in a novel rat model of nephropathic cystinosis. Hum Mol Genet. 2022;31:2262-2278 pubmed publisher
Al Brakati A, Alsharif K, Alzahrani K, Kabrah S, Al Amer O, Oyouni A, et al. Using Green Biosynthesized Lycopene-Coated Selenium Nanoparticles to Rescue Renal Damage in Glycerol-Induced Acute Kidney Injury in Rats. Int J Nanomedicine. 2021;16:4335-4349 pubmed publisher
Moroki T, Matsuo S, Hatakeyama H, Hayashi S, Matsumoto I, Suzuki S, et al. Databases for technical aspects of immunohistochemistry: 2021 update. J Toxicol Pathol. 2021;34:161-180 pubmed publisher
Kuno A, Kimura Y, Mizuno M, Oshima H, Sato T, Moniwa N, et al. Empagliflozin attenuates acute kidney injury after myocardial infarction in diabetic rats. Sci Rep. 2020;10:7238 pubmed publisher
Kalyan S, Bazett M, Sham H, Bosiljcic M, Luk B, Dhanji S, et al. Distinct inactivated bacterial-based immune modulators vary in their therapeutic efficacies for treating disease based on the organ site of pathology. Sci Rep. 2020;10:5901 pubmed publisher
Kitada M, Ogura Y, Monno I, Xu J, Koya D. Methionine abrogates the renoprotective effect of a low-protein diet against diabetic kidney disease in obese rats with type 2 diabetes. Aging (Albany NY). 2020;12:4489-4505 pubmed publisher
Imafuku A, Oka M, Miyabe Y, Sekiya S, Nitta K, Shimizu T. Rat Mesenchymal Stromal Cell Sheets Suppress Renal Fibrosis via Microvascular Protection. Stem Cells Transl Med. 2019;8:1330-1341 pubmed publisher
Kimura Y, Kuno A, Tanno M, Sato T, Ohno K, Shibata S, et al. Canagliflozin, a sodium-glucose cotransporter 2 inhibitor, normalizes renal susceptibility to type 1 cardiorenal syndrome through reduction of renal oxidative stress in diabetic rats. J Diabetes Investig. 2019;10:933-946 pubmed publisher
He Y, Diao T, Song S, Wang C, Wang Y, Zhou C, et al. Wnt4 is significantly upregulated during the early phases of cisplatin-induced acute kidney injury. Sci Rep. 2018;8:10555 pubmed publisher
Vogelaar P, Roorda M, de Vrij E, Houwertjes M, Goris M, Bouma H, et al. The 6-hydroxychromanol derivative SUL-109 ameliorates renal injury after deep hypothermia and rewarming in rats. Nephrol Dial Transplant. 2018;33:2128-2138 pubmed publisher
Ding W, Yousefi K, Goncalves S, Goldstein B, Sabater A, Kloosterboer A, et al. Osteopontin deficiency ameliorates Alport pathology by preventing tubular metabolic deficits. JCI Insight. 2018;3: pubmed publisher
Toyoda K, Suzuki Y, Muta K, Masuyama T, Kakimoto K, Kobayashi A, et al. High fructose diet feeding accelerates diabetic nephropathy in Spontaneously Diabetic Torii (SDT) rats. J Toxicol Sci. 2018;43:45-58 pubmed publisher
Chen C, Cheng B, Chen K, Shao P, Sung P, Chiang H, et al. Combination therapy of exendin-4 and allogenic adipose-derived mesenchymal stem cell preserved renal function in a chronic kidney disease and sepsis syndrome setting in rats. Oncotarget. 2017;8:100002-100020 pubmed publisher
Chen X, Cobbs A, George J, Chima A, Tuyishime F, Zhao X. Endocytosis of Albumin Induces Matrix Metalloproteinase-9 by Activating the ERK Signaling Pathway in Renal Tubule Epithelial Cells. Int J Mol Sci. 2017;18: pubmed publisher
Chen K, Chen C, Wallace C, Chen Y, Yang C, Sung P, et al. Combined therapy with melatonin and exendin-4 effectively attenuated the deterioration of renal function in rat cardiorenal syndrome. Am J Transl Res. 2017;9:214-229 pubmed
Gauer S, Urbschat A, Gretz N, Hoffmann S, Kränzlin B, Geiger H, et al. Kidney Injury Molecule-1 Is Specifically Expressed in Cystically-Transformed Proximal Tubules of the PKD/Mhm (cy/+) Rat Model of Polycystic Kidney Disease. Int J Mol Sci. 2016;17: pubmed publisher
Nozako M, Koyama T, Nagano C, Sato M, Matsumoto S, Mitani K, et al. An Atherogenic Paigen-Diet Aggravates Nephropathy in Type 2 Diabetic OLETF Rats. PLoS ONE. 2015;10:e0143979 pubmed publisher
Sereno J, Nunes S, Rodrigues Santos P, Vala H, Rocha Pereira P, Fernandes J, et al. Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat: focus on serum, urine, gene, and protein renal expression biomarkers. Biomed Res Int. 2014;2014:576929 pubmed publisher
product information
master code :
AF3689
SKU :
AF3689
product name :
Rat TIM-1/KIM-1/HAVCR Antibody
unit size :
100 ug (also 25 ug)
description :
The Rat TIM-1/KIM-1/HAVCR Antibody from R&D Systems is a goat polyclonal antibody to TIM-1/KIM-1/HAVCR. This antibody reacts with human,mouse,rat. The Rat TIM-1/KIM-1/HAVCR Antibody has been validated for the following applications: Immunohistochemistry,Neutralization,Western Blot,ELISA Capture,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.
target :
TIM-1/KIM-1/HAVCR
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant rat TIM-1/KIM-1/HAVCR, Ser18-Val238, Accession # O54947
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects rat TIM-1/KIM-1/HAVCR in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant mouse (rm) TIM-1 is observed, and less than 1% cross-reactivity with recombinant human TIM-1, recombinant rat TIM-2, rmTIM-3, rmTIM-4, rmTIM-6, and rmTIM-7 is observed.
gene symbol :
HAVCR1
top caption :
TIM-1/KIM-1/HAVCR antibody in Rat Kidney by Immunohistochemistry (IHC-Fr).
accessionNumbers :
O54947
applications :
Immunohistochemistry,Neutralization,Western Blot,ELISA Capture,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
USD :
499 USD
alt names :
CD365, HAVCR1, HAVCR-1, HAVCRT cell immunoglobin domain and mucin domain protein 1, hepatitis A virus cellular receptor 1, Kidney injury molecule 1, KIM1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIM1, TIM-1TIM, TIM1TIMD-1, TIMD1T-cell membrane protein 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.